Results 61 to 70 of about 1,746 (180)

Phospholipase D toxins of brown spider venom convert lysophosphatidylcholine and sphingomyelin to cyclic phosphates. [PDF]

PLoS ONE, 2013
Venoms of brown spiders in the genus Loxosceles contain phospholipase D enzyme toxins that can cause severe dermonecrosis and even death in humans.
Daniel M Lajoie, Pamela A Zobel-Thropp, Vlad K Kumirov, Vahe Bandarian, Greta J Binford, Matthew H J Cordes   +5 more
doaj   +1 more source

Editorial: venom collection. [PDF]

Sci Rep
Venoms are naturally available biological resources with a huge potential to explore numerous pharmacologically valuable compounds to diagnose and treat human diseases. Therefore, researching venoms is not only beneficial to develop better diagnostic and
Vaiyapuri S, Falabella P.
europepmc   +3 more sources

Histopathological characterization of experimentally induced cutaneous loxoscelism in rabbits inoculated with Loxosceles similis venom

Journal of Venomous Animals and Toxins including Tropical Diseases, 2012
Envenomation by Loxosceles bites is characterized by dermonecrotic and/or systemic features that lead to several clinical signs and symptoms called loxoscelism. Dermonecrotic lesions are preceded by thrombosis of the dermal plexus.
NB Pereira, E Kalapothakis, AC Vasconcelos, M Chatzaki, LP Campos, FO Vieira, BLA Verçosa, SS Silva, WM Ferreira, L Moro   +9 more
doaj   +1 more source

Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites. [PDF]

Nature
Each year, snakebite envenoming claims thousands of lives and causes severe injury to victims across sub-Saharan Africa, many of whom depend on antivenoms derived from animal plasma as their sole treatment option1.
Ahmadi S, Burlet NJ, Benard-Valle M, Guadarrama-Martínez A, Kerwin S, Cardoso IA, Marriott AE, Edge RJ, Crittenden E, Neri-Castro E, Fernandez-Quintero ML, Nguyen GTT, O'Brien C, Wouters Y, Kalogeropoulos K, Thumtecho S, Ebersole TW, Dahl CH, Glegg-Sørensen EU, Jansen T, Boddum K, Manousaki E, Rivera-de-Torre E, Ward AB, Morth JP, Alagón A, Mackessy SP, Ainsworth S, Menzies SK, Casewell NR, Jenkins TP, Ljungars A, Laustsen AH.   +32 more
europepmc   +3 more sources

Spider bites of medical significance in the mediterranean area: misdiagnosis, clinical features and management [PDF]

, 2020
Despite the disrepute spiders have had for centuries, their bite is a rare occurrence. In the Mediterranean area, only two of the numerous known species are considered of medical significance: Latrodectus tredecimguttatus and Loxosceles rufescens. Spider
Bennardo, Luigi, Duca, Ester Del, Fusto, Gabriele, Mazzuca, Daniela, Nisticò, Steven Paul, Patruno, Cataldo, Tamburi, Federica   +6 more
core   +1 more source

Loxoscelism: Cutaneous and Hematologic Manifestations

Advances in Hematology, Volume 2019, Issue 1, 2019., 2019
Background. Brown recluse spider (BRS) envenomation can lead to significant morbidity through severe local reaction and systemic illness including acute hemolytic anemia, rhabdomyolysis, disseminated intravascular coagulopathy (DIC), and even death. We aim to describe the clinical features and the roles of antibiotics and steroids in the treatment of ...
Ngan Nguyen, Manjari Pandey, Lawrence Rice   +2 more
wiley   +1 more source

Snakebite envenoming. [PDF]

, 2017
Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty.
Calvete, Juan J, Gutiérrez, José María, Habib, Abdulrazaq G, Harrison, Robert, Warrell, David A, Williams, David J   +5 more
core   +3 more sources

Sex‐Related Differences in Immune Response and Symptomatic Manifestations to Infection with Leishmania Species

Journal of Immunology Research, Volume 2019, Issue 1, 2019., 2019
Worldwide, an estimated 12 million people are infected with Leishmania spp. and an additional 350 million are at risk of infection. Leishmania are intracellular parasites that cause disease by suppressing macrophage microbicidal responses. Infection can remain asymptomatic or lead to a spectrum of diseases including cutaneous, mucocutaneous, and ...
Ryan D. Lockard, Mary E. Wilson, Nilda E. Rodríguez, Martin Holland   +3 more
wiley   +1 more source

Venom from Bothrops lanceolatus, a Snake Species Native to Martinique, Potently Activates the Complement System

Journal of Immunology Research, Volume 2018, Issue 1, 2018., 2018
Bothrops lanceolatus snake venom causes systemic thrombotic syndrome but also local inflammation involving extensive oedema, pain, and haemorrhage. Systemic thrombotic syndrome may lead to fatal pulmonary embolism and myocardial and cerebral infarction. Here, we investigated the ability of B.
Marie Delafontaine, Isadora Maria Villas-Boas, Giselle Pidde, Carmen W. van den Berg, Laurence Mathieu, Joël Blomet, Denise V. Tambourgi, Enrique Ortega   +7 more
wiley   +1 more source

Haemotixic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise [PDF]

, 2017
Snake venoms are mixtures of numerous proteinacious components that exert diverse functional activities on a variety of physiological targets. Because the toxic constituents found in venom vary from species to species, snakebite victims can present with ...
Abubakar, Alirol, Alirol, Amiconi, Andrião-Escarso, Antonypillai, Arlinghaus, Arnold, Berling, Calvete, Calvete, Camargo, Casewell, Casewell, Casewell, Casewell, Casewell, Chakrabarty, Chippaux, Chippaux, Chippaux, Cousin, Deshpande, Durban, Earl, Escalante, Ferreira, Flight, Flight, Fox, Fry, Fry, Funk, Greene, Gutiérrez, Gutiérrez, Habib, Han, Harrison, Harrison, Harrison, Hutton, Illig, Isbister, Isbister, Isbister, Kasturiratne, Katkar, Kerkkamp, King, Kini, Lu, Lynch, Maduwage, Markland, Marrakchi, Marsh, Massey, McCleary, Modesto, Moll, Mosquera, Moura-da-Silva, Nowak, Oyama, Peerlinck, Phillips, Pirkle, Pla, Reza, Reza, Rivel, Rosing, Rucavado, Scarborough, Segura, Shimokawa, Siigur, Silva, Smith, Stocker, Stocker, Tan, Tan, Tan, Teixeira, Triplett, Vidal, Visser, Vonk, Vonk, Warrell, Warrell, Williams, Williams, Xu, Xu, Zhang   +97 more
core   +4 more sources