Results 61 to 70 of about 1,183 (137)
Artemia salina as an animal model for the preliminary evaluation of snake venom-induced toxicity
Toxicon: X, 2021 Lethality and cytotoxicity assays of snake venoms and their neutralization by antivenom require many mice for the experiments. Recent developments have prompted researchers to seek alternative strategies that minimize the use of mice in line with Russel ...
Mitchel Otieno Okumu +6 more
doaj +1 more source
mBio, 2018 Staphylococcus aureus is a major cause of morbidity and mortality worldwide. S. aureus colonizes 20 to 80% of humans at any one time and causes a variety of illnesses. Strains that are resistant to common antibiotics further complicate management.
Fan Zhang +5 more
doaj +1 more source
Revista Brasileira em Promoção da Saúde, 2012 The loxoscelism is the most serious form of arachnidism in Brazil. The genus Loxosceles comprises more than 100 species of spiders in African and American continents. In Brazil, they are known as brown spiders.
Ricardo Marques Frezza
doaj +1 more source
Human Vaccines & Immunotherapeutics, 2017 Staphylococcus aureus is the leading cause of nosocomial and community-acquired infections, including soft tissue and skin infections and bacteremia. However, efforts to develop an effective vaccine against S.
Brian L. Cheng +8 more
doaj +1 more source
mBio, 2016 Staphylococcus aureus produces numerous virulence factors, each contributing different mechanisms to bacterial pathogenesis in a spectrum of diseases. Alpha toxin (AT), a cytolytic pore-forming toxin, plays a key role in skin and soft tissue infections ...
C. Tkaczyk +13 more
doaj +1 more source
Toxins, 2019 Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological disturbances. Several toxins make
Daniele Chaves-Moreira +11 more
doaj +1 more source
, 2017 Widespread antibiotic resistance is on the rise and current therapies are becoming increasingly limited in both scope and efficacy. Methicillin-resistant Staphylococcus aureus (MRSA) represents a major contributor to this trend. Quorum sensing controlled
Cassandra L. Quave +6 more
core +1 more source
Extracellular matrix molecules as targets for brown spider venom toxins
Brazilian Journal of Medical and Biological Research, 2001 Loxoscelism, the term used to describe lesions and clinical manifestations induced by brown spider's venom (Loxosceles genus), has attracted much attention over the last years. Brown spider bites have been reported to cause a local and acute inflammatory
S.S. Veiga +4 more
doaj +1 more source
Experimental pathology of local tissue damage induced by Bothrops asper snake venom [PDF]
, 2009 Envenomations by Bothrops asper are often associated with complex and severe local pathological manifestations, including edema, blistering, dermonecrosis, myonecrosis and hemorrhage.
Rucavado Romero, Alexandra +4 more
core +1 more source
Interruption of the pentose phosphate pathway attenuates S. aureus pathogenesis.
, 2023 Strains of S. aureus USA300 were inoculated into mice to assess pathogenicity. A) Model of acute pneumonia using intranasal infection, n = 6. B) Sepsis model using intraperitoneal inoculation. n = 23 for WT and 20 for others.
Dane Parker (76619) +4 more
core +1 more source