Results 81 to 90 of about 12,988 (223)

Bioinspired superwetting SERS substrate based on femtosecond laser processing: Principles, methods, and applications

Droplet
The growing demand for surface‐enhanced Raman scattering sensors in biochemical detection, environmental monitoring, microfluidics, and other fields has promoted the development of highly sensitive and stable substrates.
Jinglan Huo, Xubo Huang, Jiangfeng Zhu
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Exploring anomalous nanofluidic transport at the interfaces

Droplet
Transport of ions and water is essential for diverse physiological activities and industrial applications. As the dimension approaches nano and even angstrom scale, ions and water exhibit anomalous behaviors that differ significantly from the bulk.
Shengping Zhang, Ruiyang Song, Haiou Zeng, Ningran Wu, Hongwei Duan, Luda Wang   +5 more
doaj   +1 more source

The energetic and experimental based approach to description of basic material characteristics and mechanical properties of selected polymers

Journal of Theoretical and Applied Mechanics, 2020
Dariusz Kurpisz, Maciej Obst
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Coarsening droplets for frosting delay on hydrophilic slippery liquid‐infused porous surfaces

Droplet
Frosting occurs due to the freezing of condensed water droplets on a supercooled surface. The nucleated frost propagates through interdroplet bridges and covers the entire surface, resulting from the deposition of highly supersaturated vapor surrounding ...
Jyotirmoy Sarma, Deepak Monga, Zongqi Guo, Fangying Chen, Xianming Dai   +4 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Droplet Laplace valve‐enabled glaucoma implant for intraocular pressure management

Droplet
Glaucoma, the leading cause of irreversible blindness worldwide, is closely linked to aqueous overaccumulation and elevated intraocular pressure (IOP).
Yuyang Wang, Zecong Fang, Sen Li, Kexin Lin, Zhifeng Zhang, Junyi Chen, Tingrui Pan   +6 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source