Results 41 to 50 of about 412,458 (245)

Experimental modeling of desensitization: What have we learned about preventing AMR?

open access: yesAmerican Journal of Transplantation, 2020
During the past 5 decades, short‐term outcomes in kidney transplant have significantly improved, in large part due to reduced rates and severity of acute rejection.
J. Kwun, S. Knechtle
semanticscholar   +1 more source

A Marine Analgesic Peptide, Contulakin-G, and Neurotensin are Distinct Agonists for Neurotensin Receptors: Uncovering Structural Determinants of Desensitization Properties

open access: yesFrontiers in Pharmacology, 2015
Neurotensin receptors have been studied as molecular targets for the treatment of pain, schizophrenia, addiction, or cancer. Neurotensin (NT) and Contulakin-G, a glycopeptide isolated from a predatory cone snail Conus geographus, share a sequence ...
Hee-Kyoung eLee   +10 more
doaj   +1 more source

The Efficacy of a New Protocol of Oral Immunotherapy to Wheat for Desensitization and Induction of Tolerance

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2022
Oral immunotherapy (OIT) is a novel approach to desensitization and tolerance induction in food allergy patients. This study aimed to design and implement a new wheat OIT protocol, evaluate its efficacy in tolerance induction, and assess specific ...
Samin Sharafian   +6 more
doaj   +1 more source

Clinical immunology review series: an approach to desensitization

open access: yesClinical and Experimental Immunology, 2010
Summary Allergen immunotherapy describes the treatment of allergic disease through administration of gradually increasing doses of allergen. This form of immune tolerance induction is now safer, more reliably efficacious and better understood than when it was first formally described in 1911.
M T, Krishna, A P, Huissoon
openaire   +3 more sources

Oral Immunotherapy for Food Allergy: Towards a New Horizon [PDF]

open access: yes, 2013
Food allergy has increased dramatically in prevalence over the past decade in westernized countries, and is now a major public health problem. Unfortunately for patients with food allergy, there is no effective therapy beyond food allergen avoidance, and
Khoriaty, Evelyne Nassim   +1 more
core   +1 more source

Immunological barriers in ABO-incompatible kidney transplantation: How to overcome

open access: yesIndian Journal of Transplantation, 2019
Background: Various desensitization strategies are used to overcome immunologic barriers such as anti-human leukocyte antigen-donor-specific antibody (HLA-DSA) and anti-ABO blood group incompatibility.
Sonia Mehrotra, Raj Kumar Sharma
doaj   +1 more source

Pea proteins immunotherapy in peanut allergic mice model [PDF]

open access: yes, 2014
Mice (Balb/c), with peanut allergy induced, were subjected to desensitization therapy with the use of pea protein extract (PE) or isolated globulin fractions: legumin (PL) and vicilin (PV).
Chudzik-Kozłowska, J., Szymkiewicz, A.
core   +1 more source

A practical view of immunotherapy for food allergy [PDF]

open access: yesKorean Journal of Pediatrics, 2016
Food allergy is common and sometimes life threatening for Korean children. The current standard treatment of allergen avoidance and self-injectable epinephrine does not change the natural course of food allergy.
Tae Won Song
doaj   +1 more source

Aspirin desensitisation therapy for aspirin-intolerant chronic rhinosinusitis [PDF]

open access: yes, 2009
This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2009, Issue 4. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic
Lipworth, Brian J.   +2 more
core   +3 more sources

The effect of lipopolysaccharide desensitization on the regulation of in vivo induction of immunologic tolerance and antibody production and in vitro release of IL-1.

open access: yesJournal of Immunology, 1989
As previously reported, LPS and 8-derivatized guanosine (both generators of IL-1 release), as well as IL-1 itself interfere with the in vivo induction of tolerance to DHGG in A/J mice.
W. Weigle   +3 more
semanticscholar   +1 more source

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