Results 81 to 90 of about 7,110 (229)

Alergia e intolerancia a antiinflamatorios no esteroides: desensibilización exitosa en tres casos y revisión de la literatura

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2009
Los antiinflamatorios no esteroides son la segunda causa de reacciones a medicamentos después de los beta-lactámicos. La prevalencia de las reacciones a antiinflamatorios no esteroideos en la población general es de 0,1% a 0,3% y la prevalencia de ...
Ricardo Cardona   +4 more
doaj   +1 more source

Desensitized Cubature Kalman Filter with Uncertain Parameter [PDF]

open access: yesarXiv, 2015
A robust desensitized cubature Kalman filtering (DCKF) for nonlinear systems with uncertain parameter is proposed. Sensitivity matrices are defined as the integral form, and desensitized cost function is designed by penalizing the posterior covariance trace by a sensitivity-weighting sum of the posteriori sensitivities.
arxiv  

A statistical mechanics approach to autopoietic immune networks [PDF]

open access: yes, 2010
The aim of this work is to try to bridge over theoretical immunology and disordered statistical mechanics. Our long term hope is to contribute to the development of a quantitative theoretical immunology from which practical applications may stem. In order to make theoretical immunology appealing to the statistical physicist audience we are going to ...
arxiv   +1 more source

Robustness-enhanced Uplift Modeling with Adversarial Feature Desensitization [PDF]

open access: yesarXiv, 2023
Uplift modeling has shown very promising results in online marketing. However, most existing works are prone to the robustness challenge in some practical applications. In this paper, we first present a possible explanation for the above phenomenon. We verify that there is a feature sensitivity problem in online marketing using different real-world ...
arxiv  

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

open access: yesAndrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre   +5 more
wiley   +1 more source

Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates

open access: yesBlood Advances, 2017
: The detrimental effects of donor-directed antibodies in sensitized transplant patients remain a difficult immunologic barrier to successful organ transplantation. Antibody removal is often followed by rebound.
Jean Kwun   +12 more
doaj  

Latex immunotherapy: evidence of effectiveness. [PDF]

open access: yes, 2018
Introduction: The only etiological and decisive therapy, able to influence the natural history of latex allergy is the specific desensitization. Aim: To verify the clinical efficacy and immunological changes determined by latex sublingual immunotherapy
Aruanno, A   +8 more
core   +1 more source

Arrestin‐centred interactions at the membrane and their conformational determinants

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract More than 30 years after their discovery, arrestins are recognised multiprotein scaffolds that play essential roles in G protein‐coupled receptor (GPCR) regulation and signalling. Originally named for their capacity to hinder GPCR coupling to G proteins and facilitate receptor desensitisation, arrestins have emerged as key hubs for a myriad of
Owen Underwood   +3 more
wiley   +1 more source

A Cost-Utility Analysis of SQ® Tree SLIT-Tablet versus Placebo in the Treatment of Birch Pollen Allergic Rhinitis from a Swedish Societal Perspective

open access: yesClinicoEconomics and Outcomes Research, 2023
Richard F Pollock,1 Andreas K Slættanes,2 Henrik Brandi,2 Tobias Sydendal Grand2 1Covalence Research Ltd, Harpenden, UK; 2ALK-Abelló A/S, Hørsholm, DenmarkCorrespondence: Andreas K Slættanes, ALK-Abelló A/S, Bøge Allé 1, Hørsholm, DK-2970, Denmark, Tel ...
Pollock RF   +3 more
doaj  

Drug Allergy [PDF]

open access: yes, 2014
Egypt J Pediatr Allergy Immunol 2013; 11(1):3 ...
El-Owaidy, Rasha H
core   +2 more sources

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