Results 41 to 50 of about 2,107,565 (334)

Successful desensitization in a patient with hypersensitivity to multiple insulin preparations - case report

Medicine and Pharmacy Reports, 2020
Hypersensitivity to insulin has decreased substantially in the past three decades, since purified human insulin was introduced to replace heterogeneous porcine and bovine preparations.
Carina Petricău, I. Nedelea, D. Deleanu
semanticscholar   +1 more source

Mechanisms of synaptic depression at the hair cell ribbon synapse that support auditory nerve function [PDF]

, 2017
Inner hair cells (IHCs) in the cochlea are the mammalian phono-receptors, transducing sound energy into graded changes in membrane potentials, the so called “receptor potentials.” Ribbon synapses between IHCs and auditory nerve neurons are responsible ...
Goutman, Juan Diego
core   +1 more source

DRESS syndrome and tuberculosis: Implementation of a desensitization and re-desensitization protocol to recover antituberculosis drugs in a case series at a specialized TB Unit in Lima, Peru

Medicine
Rationale: Antituberculosis drugs (ATDs) could cause severe and rare reactions, such as Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome. Recovering ATDs might guarantee a higher cure rate for tuberculosis patients.
C. Morán-Mariños, F. Llanos-Tejada, J. Salas-López, Renzo Villanueva-Villegas, A. Chavez-Huamani, María Vidal-Ruiz, Aaron Rodriguez-Calienes, R. Casanova-Mendoza   +7 more
semanticscholar   +1 more source

Successful Desensitization Treatment with Osimertinib after the Development of Osimertinib-induced Urticaria in a Patient Undergoing Treatment for Non-small Cell Lung Cancer Harboring the EGFR T790M Mutation

Internal medicine, 2020
Some patients discontinue receiving osimertinib for non-small cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) Thr790Met (T790M) mutation due to adverse its effects.
Go Makimoto, T. Nishi, K. Kawakado, Tomoka Nishimura, T. Tamura, K. Kudo, S. Kuyama   +6 more
semanticscholar   +1 more source

Use of Skin Testing Screening and Desensitization Before the First Exposure of Rituximab

Cancer Management and Research, 2021
Lisha Li,1 Lianglu Wang,1 Kai Guan,1 Jun Liu,1 Daobin Zhou,2 Yanbin Zhang,2 Yan Zhang2 1Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Precision ...
Li L, Wang L, Guan K, Liu J, Zhou D, Zhang Y, Zhang Y   +6 more
doaj  

Successful Desensitization with Imlifidase and Daratumumab in a Highly Immunized, Crossmatch Positive, Blood Group-Incompatible Living-Donor Re-Transplant Recipient with Systemic Lupus Erythematosus and Antiphospholipid Syndrome

Transfusion Medicine and Hemotherapy
Introduction: The transplantation of highly sensitized patients remains a major obstacle. Immunized patients wait longer for a transplant if not prioritized, and if transplanted, their transplant outcome is worse.
E. Schrezenmeier, Mira Choi, B. Globke, T. Dörner, Alexandra Leimbach, B. Osmanodja, Alexander Schramm, Kerstin Amann, K. Eckardt, K. Budde, R. Öllinger, N. Lachmann, F. Halleck   +12 more
semanticscholar   +1 more source

Lymphoid differentiation of hematopoietic stem cells requires efficient Cxcr4 desensitization

Journal of Experimental Medicine, 2017
The CXCL12/CXCR4 signaling exerts a dominant role in promoting hematopoietic stem and progenitor cell (HSPC) retention and quiescence in bone marrow.
C. Freitas, M. Wittner, Julie V. Nguyen, V. Rondeau, Vincent Biajoux, Marie-Laure Aknin, F. Gaudin, S. Beaussant-Cohen, Y. Bertrand, C. Bellanné-Chantelot, J. Donadieu, F. Bachelerie, M. Espéli, A. Dalloul, F. Louache, K. Balabanian   +15 more
semanticscholar   +1 more source

Usefulness of Rapid Desensitization Therapy for Severe Rash Caused by Molecularly Targeted Drugs Used in the Treatment of Non-small-cell Lung Cancer

Internal medicine, 2020
Molecular-targeted drugs (MTDs), such as epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and anaplastic lymphoma kinase inhibitors, are used to treat non-small-cell lung cancer (NSCLC).
Maki Nagase, Nobuharu Ohshima, M. Kawashima, M. Ohgiya, Miki Ikeda, Y. Morio, A. Tamura   +6 more
semanticscholar   +1 more source

The feasibility of organ transplantation during the COVID-19 outbreak: experiences from South Korea

Korean Journal of Transplantation, 2020
Background : The coronavirus disease 2019 (COVID-19) has forced healthcare systems to reduce transplant activities in order to preserve resources and minimize the risk of nosocomial transmission.
Juhan Lee, Eun Jin Kim, Kyong Ihn, Jae Geun Lee, Dong Jin Joo, Myoung Soo Kim, Soon Il Kim, Yu Seun Kim, Kyu Ha Huh   +8 more
doaj   +1 more source

Stimulation of electro-olfactogram responses in the main olfactory epithelia by airflow depends on the type 3 adenylyl cyclase [PDF]

, 2012
Cilia of olfactory sensory neurons are the primary sensory organelles for olfaction. The detection of odorants by the main olfactory epithelium (MOE) depends on coupling of odorant receptors to the type 3 adenylyl cyclase (AC3) in olfactory cilia.
Chen, Xuanmao, Storm, Daniel R., Xia, Zhengui   +2 more
core   +2 more sources