Results 101 to 110 of about 7,828,613 (296)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Class structure of electromechanical energy converter models with UML-diagrams application

open access: yesElectrical engineering & Electromechanics, 2014
Theoretical results are presented, mathematical model formation by means of inheritance from a generalized class template is shown for a general electromechanical energy converter.
V.Ye. Plyugin
doaj  

Design não é só design [design is not only design]

open access: yes, 2022
This poster was developed based on the backgrounds of the design faculty that participated in the survey launched by the DesignOBS project in 2021. The visualisation was commissioned by the team of the DesignOBS project (Towards a Design Observatory in Portugal, www.designobs.pt), following a distributed and participatory approach.
openaire   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

G-designs and related designs

open access: yesDiscrete Mathematics, 1993
Let \(G\) be a graph with \(k\) vertices and \(\lambda K_ v\) the complete multigraph with \(v\) vertices in which any two distinct vertices are joined by exactly \(\lambda\) edges. A \((v,k,\lambda)\) \(G\)-design is an edge-disjoint decomposition of \(\lambda K_ v\) into \(b\) subgraphs isomorphic to \(G\).
openaire   +3 more sources

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Editorial: Peptidomimetics: Synthetic Tools for Drug Discovery and Development

open access: yesFrontiers in Chemistry, 2021
Annarita Del Gatto   +5 more
doaj   +1 more source

Art, design, science, and technology: the necessary melding

open access: yesDearq, 2011
This paper endeavors to detail the importance of design education and how it helps to prepare students for the challenges that they will face in the design profession. The text is divided into five parts.
Monica Tavares
doaj  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

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