Results 101 to 110 of about 20,281,979 (291)
Looking for Design in Materials Design
Despite great advances in computation, materials design is still science fiction. The construction of structure-property relations on the quantum scale will turn computational empiricism into true design.Comment: 3 pages, 1 ...
CS Smith +5 more
core +1 more source
Analytical Method for the Deformation-Based Design of Retaining Walls in Asymmetric Excavation
Conventional methods for designing retaining structures are not applicable to asymmetric excavation or deformation-based designs. This study proposes a quadruple-line displacement-dependent earth pressure coefficient model.
Xiaozhen Fan +4 more
doaj +1 more source
Strategies For Managing and Maintaining Green Infrastructure: Review [PDF]
Green spaces are essential infrastructures for improving quality of life, promoting biodiversity and responding to environmental challenges in urban areas. Their management requires a systemic approach combining strategic planning and regular maintenance.
Chkird Fadoua +7 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Realising intelligent virtual design [PDF]
This paper presents a vision and focus for the CAD Centre research: the Intelligent Design Assistant (IDA). The vision is based upon the assumption that the human and computer can operate symbiotically, with the computer providing support for the human ...
Duffy, A.H.B., Whitfield, R.I., Wu, Z.
core
Code Requirements for the Seismic Design of Irregular Elevation RC Structures
The recent seismic activity highlights the crucial need to enhance seismic design and safety assessment methods, particularly for irregular structures, in both new and existing constructions.
Davi Santos, José Melo, Humberto Varum
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Local Fabric: Mid-Century Modernisms, Textile and Fashion Design, and the Northwest Coast, 1940–1967
In the mid-twentieth century, growing North American textile and ready-to-wear industries vigorously appropriated Native American aesthetics to cultivate a commercial and design identity apart from Europe.
Laura J. Allen
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

