Results 121 to 130 of about 4,753,099 (348)

Creative vs Defective: A Critical Review of Malang Creative Center (MCC) in Malang City

open access: yesRUAS
The Malang Creative Center (MCC) construction is a step taken by the Malang City government to support the flow of modernization and as a forum for Malang residents to develop their creativity. The MCC display concept is planned by combining the shape of
Bunga Pasadena Ineru   +4 more
doaj   +1 more source

THE CONCEPTUAL DESIGN OF A SUSTAINABLE REGIONAL AIRCRAFT

open access: yesJournal of Industrial Design and Engineering Graphics, 2021
This paper aims to present the conceptual design of a sustainable regional aircraft. In previous studies, the hypothesis of this paper was determined: the purpose is to design a concept sustainable regional aircraft, propelled by electric engines ...
Ioana-Lidia MOTFOLEA
doaj  

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Concept design of a fast sail assisted feeder container ship

open access: yes, 2010
A fast sail assisted feeder container ship concept has been developed for the 2020 container market in the South East Asian and Caribbean regions.The design presented has met the requirements of an initial economic study, with a cargo capacity of 1270 ...
Burden, Aaron   +5 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Design as a Literary Concept? [PDF]

open access: yesSlovenska Literatura, 2014
In relation to his book Černá kočka aneb Subjekt znalce v myšlení o literatuře a jeho komunikační strategie (A Black Cat or The Subject of the Expert in Literary Thinking and His Communication Strategies, Praha, Academia 2012), the writer of the article ...
Pavel Janoušek
doaj  

An analysis of design reuse benefits [PDF]

open access: yes, 1998
Although the concept of design reuse is accepted as a valid approach to design, little attempt has been made to formalise the elements that constitutes design reuse. The few approaches formalising design reuse, e.g.
Duffy, A.H.B., Ferns, A. F.
core  

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