Results 61 to 70 of about 5,666,479 (292)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Insights from a Latent Semantic Analysis of Patterns in Design Expertise: Implications for Education
Education Sciences, 2019 Design and design thinking are increasingly being taught across several disciplines—ranging from arts, architecture, and technology and engineering to business schools—where expertise plays a central role.
Hernan Casakin, Vishal Singh
doaj +1 more source
DESIGN THINKING AND ART EDUCATION
Sanat ve Tasarım Dergisi, 2022 Design Thinking is a collaborative, interdisciplinary, innovative, creative, problem-solving and human-centered process for creating user-oriented products, services or experiences. Because of its ability to foster creativity and innovation, it is applied in the fields of industry, business, engineering, technology and education by applying an ...
openaire +3 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Improving Basic Design courses through Competences of Tuning MEDA
Tuning Journal for Higher Education, 2016 It is well established that Tuning’s development of the concept of competences for the improvement of what is referred to as student-centered approach has proven itself beneficial in developing higher education programs.[1] This paper examines the ...
Rafee Hakky
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
The Changing Ideals of ‘Individual Creativity & Traits in Bauhaus’ Preliminary Course
PLANARCH - Design and Planning ResearchThe Bauhaus school, founded in the early 20th century by Walter Gropius, became a leading institution for art, design, and architectural education. Gropius' vision emphasized abolishing the distinctions between different branches of art & design, and ...
A. Derin İnan
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Educating educational designers
, 2007 How do you efficiently and effectively educate students to be academically competent and practice-orientededucational designers when they lack prior design experience? This papers provides an answer to this question bydescribing and discussing a four-year University program in instructional design and educational technology.
Visscher-Voerman, Irene +2 more
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Scrutinizing design educators' perceptions of the design process
Artificial Intelligence for Engineering Design, Analysis and Manufacturing, 2010 AbstractWhen developing a better understanding of the design process there are several possible approaches to choose from. Many studies are based on novice designers (e.g., students) or designers of relatively modest talents. By contrast, some studies have queried designers who are considered to have outstanding and exceptional ability in order to gain
Strickfaden, Megan, Heylighen, Ann
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source