Results 91 to 100 of about 7,219,960 (314)

A knowledge based expert system for moulded part design [PDF]

, 2007
In today's competitive market many consumer products are designed with complex curved shapes to meet customers' demands for styling and ergonomics. These styled products are commonly manufactured using moulding processes because they can produce a wide ...
Guenov, Marin, Lockett, Helen
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A Computer-Supported Framework for Form Analysis [PDF]

Journal of Systemics, Cybernetics and Informatics
Although there are several frameworks for the synthesis of form, and for the automated development of geometric shapes, studies in the systematic analysis of architectural forms and their automation are still underrepresented.
Buthayna Eilouti
doaj  

A Broad Study to Develop Maternity Units Design Knowledge Combining Spatial Analysis and Mothers' and Midwives' Perception of the Birth Environment. [PDF]

HERD, 2022
Nicoletta S, Eletta N, Cardinali P, Migliorini L.   +3 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Quality Control Methods Using Quality Characteristics in Development and Operations

Digital
Since the Software Quality Model was defined as an international standard, many quality assurance teams have used this quality model in a waterfall model for software development and quality control.
Daiju Kato, Hiroshi Ishikawa
doaj   +1 more source

Design Management Knowledge

Conference Proceedings of the Academy for Design Innovation Management, 2019
Design-management knowledge is of a cross-functional and multidisciplinary nature. Since the stakeholders’ realms of activities as well as their background are diverse, it is expected that their needs for knowledge-learning will also be diverse. In this context, this paper addresses a new way of learning design management knowledge.
Ki-Young NAM, Gye Young KIM, Brigitte BORJA DE MOZOTA   +2 more
openaire   +1 more source

SPIDA: Abstracting and generalizing layout design cases [PDF]

, 1998
ion and generalization of layout design cases generate new knowledge that is more widely applicable to use than specific design cases. The abstraction and generalization of design cases into hierarchical levels of abstractions provide the designer with ...
Duffy, A.H.D., Lee, B.S., Manfaat, D.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Fostering continuous innovation in design with an integrated knowledge management approach

, 2011
In the global competition, companies are propelled by an immense pressure to innovate. The trend to produce more new knowledge-intensive products or services and the rapid progress of information technologies arouse huge interest on knowledge management ...
Caillaud, Emmanuel, Gardoni, Mickaël, Houssin, Rémy, Xu, J.   +3 more
core   +3 more sources