Results 61 to 70 of about 3,978,056 (320)

Formulation and Evaluation of Multidose Propofol Nanoemulsion Using Statistically Designed Experiments

open access: yesActa Chimica Slovenica, 2020
Despite of the clinical, scientific, and commercial development, many patients complain about pain on the intravenous injection of propofol. Present work was undertaken to develop a stable multi-dose propofol nano-emulsion using 32 full factorial design ...
Sidhartha Sankar Hota   +2 more
doaj   +1 more source

A first investigation into the effectiveness of Tactons [PDF]

open access: yes, 2005
This paper reports two experiments relating to the design of Tactons (or tactile icons). The first experiment investigated perception of vibro-tactile "roughness" (created using amplitude modulated sinusoids), and the results indicated that roughness ...
Brewster, S.A.   +2 more
core   +3 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

CASE STUDIES OF USE OF DESIGN OF EXPERIMENTS IN MATERIAL RESEARCH

open access: yesJurnal Teknik Industri, 2003
The paper describes principles of factorial and fractional factorial design of experiments. The various ways of analysing data obtained by these procedures are shown via four case studies.
Salil Kumar Roy, I Nyoman Sutapa
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The outline of the expert system for the design of experiment

open access: yesProduction Engineering Archives, 2018
The design of experiment (DoE) is a methodology originated from early 1920s when Fisher’s papers created the analysis of variance and first known experimental designs: latin squares.
Dwornicka Renata, Pietraszek Jacek
doaj   +1 more source

Surface Response Methodology-Based Mixture Design to Study the Influence of Polyol Blend Composition on Polyurethanes’ Properties

open access: yesMolecules, 2018
Polyurethanes are materials with a strong structure-property relationship. The goal of this research was to study the effect of a polyol blend composition of polyurethanes on its properties using a mixture design and setting mathematic models for each ...
Said Arévalo-Alquichire   +3 more
doaj   +1 more source

Design of and Experiment with Secondary Cutting Equipment for Broccoli [PDF]

open access: gold, 2022
Jiangming Jia   +4 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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