Results 71 to 80 of about 3,978,056 (320)

The Response Surface Methodology revisited – comparison of analytical and non-parametric approaches

open access: yesProduction Engineering Archives, 2018
Since G.E.P. Box introduced central composite designs in early fifties of 20th century, the classic design of experiments (DoE) utilizes response surface models (RSM), however usually limited to the simple form of low-degree polynomials.
Osocha Przemysław, Podgórski Jordan
doaj   +1 more source

Optimal Designs to Develop and Support an Experimental Strategy on Innovation of Thermoforming Production Process

open access: yesStatistica, 2017
The experimental strategy developed thanks to the DOE methodology enhance innovation capability in the field of thermoforming production processes for active packaging. It is composed of three phases: i) material characterization, ii) production in pilot
Fabrizio Ronchi   +6 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Development of headspace solid-phase microextraction method for the analysis of pesticide residues in fruit and vegetable samples using OFAT design

open access: yesJournal of Applied Sciences and Environmental Management, 2017
A headspace solid-phase microextraction (HS-SPME) method was developed as a preliminary investigation using univariate approach for the analysis of 14 multiclass pesticide residues in fruits and vegetable samples.
Lukman Bola Abdulra’uf   +2 more
doaj   +1 more source

Preliminary design of the redundant software experiment [PDF]

open access: yes
The goal of the present experiment is to characterize the fault distributions of highly reliable software replicates, constructed using techniques and environments which are similar to those used in comtemporary industrial software facilities.
Campbell, Roy   +8 more
core   +1 more source

Design and performance of the muon monitor for the T2K neutrino oscillation experiment

open access: yes, 2010
This article describes the design and performance of the muon monitor for the T2K (Tokaito-Kamioka) long baseline neutrino oscillation experiment. The muon monitor consists of two types of detector arrays: ionization chambers and silicon PIN photodiodes.
A. Murakami   +27 more
core   +1 more source

COMPASS: a 2.6m telescope for CMBR polarization studies [PDF]

open access: yes, 2002
COMPASS (COsmic Microwave Polarization at Small Scale) is an experiment devoted to measuring the polarization of the CMBR.
Dall'Oglio, G.   +11 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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