Results 31 to 40 of about 17,265,464 (329)

Wiring optimization explanation in neuroscience: What is Special about it? [PDF]

open access: yes, 2019
This paper examines the explanatory distinctness of wiring optimization models in neuroscience. Wiring optimization models aim to represent the organizational features of neural and brain systems as optimal (or near-optimal) solutions to wiring ...
Barberis, Sergio Daniel
core   +6 more sources

High-dimensional aerodynamic data modeling using a machine learning method based on a convolutional neural network

open access: yesAdvances in Aerodynamics, 2022
Modeling high-dimensional aerodynamic data presents a significant challenge in aero-loads prediction, aerodynamic shape optimization, flight control, and simulation.
Bo-Wen Zan   +4 more
doaj   +1 more source

Optimal Experimental Designs

open access: yesThe Annals of Mathematical Statistics, 1966
Abstract : This paper presents a number of results concerning the theory of the optimal design of experiments initiated and principal developed by Elfving, Kiefer and Wolfowitz. The paper contains approximately half expository and half new material. The proofs are mostly new and presented in a unified manner.
Karlin, Samuel, Studden, William J.
openaire   +2 more sources

An aerothermodynamic design optimization framework for hypersonic vehicles [PDF]

open access: yes, 2018
In the aviation field great interest is growing in passengers transportation at hypersonic speed. This requires, however, careful study of the enabling technologies necessary for the optimal design of hypersonic vehicles.
Di Giorgio, Simone   +3 more
core   +1 more source

Optimal experimental design for optimal process design: A trilevel optimization formulation

open access: yesAIChE Journal, 2019
AbstractTypical optimal experimental design (OED) methods aim at minimizing the covariance matrix of the estimated parameters regardless of the intended application of the model that is being estimated. This can unnecessarily increase the experimental costs.
Walz, Olga   +2 more
openaire   +3 more sources

‘Click Chemistry’ Synthesis of Novel Natural Product-Like Caged Xanthones Bearing a 1,2,3-Triazole Moiety with Improved Druglike Properties as Orally Active Antitumor Agents

open access: yesMolecules, 2017
DDO-6101, a natural-product-like caged xanthone discovered previously in our laboratory based on the pharmacophoric scaffold of the Garcinia natural product gambogic acid (GA), shows potent cytotoxicity in vitro, but poor efficacy in vivo due to its poor
Xiang Li   +4 more
doaj   +1 more source

Casting Design Optimization for Steam Turbine Emergency Stop Valve (ESV) Housing with Computational Casting Simulation Method [PDF]

open access: yes, 2018
Design optimization casting emergency stop valve steam turbine, has been done with casting simulation using Magmasoft v5 software. By simulation, some casting design parameters are changed to get more optimal results.
F, B. N. (Budi)   +3 more
core   +1 more source

A comprehensive review of cycloastragenol: Biological activity, mechanism of action and structural modifications

open access: yesEuropean Journal of Medicinal Chemistry Reports, 2022
Cycloastragenol (CAG) is a sapogenin of Astragaloside IV (AG-IV), isolated from the dried roots of legumes Astragalus mongolica or Astragalus membranaceus.
Mengting He   +7 more
doaj   +1 more source

Flow structures and wall parameters on rotating riblet disks and their effects on drag reduction

open access: yesAlexandria Engineering Journal, 2022
The demand of energy saving and loss mitigation in modern industry gives rise to drag reduction techniques such as micro groove/riblet ever since the last century.
Tong Liang   +3 more
doaj   +1 more source

Generative Adversarial Networks (GANs): Challenges, Solutions, and Future Directions

open access: yes, 2020
Generative Adversarial Networks (GANs) is a novel class of deep generative models which has recently gained significant attention. GANs learns complex and high-dimensional distributions implicitly over images, audio, and data. However, there exists major
Cao, Jiannong, Saxena, Divya
core   +1 more source

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