Results 51 to 60 of about 17,265,464 (329)

Bayesian optimization for materials design

, 2015
We introduce Bayesian optimization, a technique developed for optimizing time-consuming engineering simulations and for fitting machine learning models on large datasets.
A Booker, A Forrester, AB Gelman, AIJ Forrester, B Ankenman, BE Stuckman, CE Rasmussen, D Huang, D Huang, David Ginsbourger, Diana M. Negoescu, DR Jones, HJ Kushner, J Bect, J Knowles, J Mockus, J Villemonteix, J Xie, LP Kaelbling, Noel Cressie, PI Frazier, PI Frazier, PI Frazier, R Waeber, RA Howard, RS Sutton, Sethuraman Sankaran, TJ Santner, W Scott   +28 more
core   +1 more source

Efficient design optimization of complex electromagnetic systems using parametric macromodeling techniques [PDF]

, 2011
We propose a new parametric macromodeling technique for complex electromagnetic systems described by scattering parameters, which are parameterized by multiple design variables such as layout or substrate feature.
Antonini, Giulio, Dhaene, Tom, Ferranti, Francesco, Knockaert, Luc, Scogna, Antonio Ciccomancini   +4 more
core   +2 more sources

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Design Optimization of a Multi-Megawatt Wind Turbine Blade with the NPU-MWA Airfoil Family

Energies, 2019
A new airfoil family, called NPU-MWA (Northwestern Polytechnical University Multi-megawatt Wind-turbine A-series) airfoils, was designed to improve both aerodynamic and structural performance, with the outboard airfoils being designed at high design lift
Jianhua Xu, Zhonghua Han, Xiaochao Yan, Wenping Song   +3 more
doaj   +1 more source

A hydrogen peroxide responsive prodrug of Keap1-Nrf2 inhibitor for improving oral absorption and selective activation in inflammatory conditions

Redox Biology, 2020
Transcription factor Nuclear factor erythroid 2-related factor 2 (Nrf2) and its negative regulator, the E3 ligase adaptor Kelch-like ECH-associated protein 1 (Keap1), control the redox and metabolic homeostasis and oxidative stress.
Mengchen Lu, Xian Zhang, Jing Zhao, Qidong You, Zhengyu Jiang   +4 more
doaj   +1 more source

PTPN2, A Key Predictor of Prognosis for Pancreatic Adenocarcinoma, Significantly Regulates Cell Cycles, Apoptosis, and Metastasis

Frontiers in Immunology, 2022
ObjectiveThis study conducted a comprehensive analysis of the members of the PTPN family and emphasized the key role of PTPN2 as a potential therapeutic target and diagnostic biomarker in improving the survival rate of PAAD.MethodOncomine was used to ...
Wenbin Kuang, Wenbin Kuang, Xiao Wang, Xiao Wang, Jiayu Ding, Jiayu Ding, Jiaxing Li, Jiaxing Li, Minghui Ji, Minghui Ji, Weijiao Chen, Weijiao Chen, Liping Wang, Liping Wang, Peng Yang, Peng Yang   +15 more
doaj   +1 more source

Optimization of broaching design [PDF]

, 2007
Broaching is one of the most recognized machining processes that can yield high productivity and high quality when applied properly. One big disadvantage of broaching is that all process parameters, except cutting speed, are built into the broaching ...
Budak, Erhan, Ozelkan, Ertunga, Ozturk, Ozkan, Özelkan, Ertunga, Öztürk, Özkan   +4 more
core  

EXOhSPEC folded design optimization and performance estimation [PDF]

, 2019
The EXOplanet high resolution SPECtrograph (EXOhSPEC) instrument is an echelle spectrograph dedicated to the detection of exoplanets by using the radial velocity method using 2m class telescopes.
Buisset, Christophe, Errmann, Ronny, Jones, Hugh, Lhospice, Esther, Martin, Bill   +4 more
core   +2 more sources

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

100 kW, 10 kHz Medium-Frequency Transformer Design Optimization and Experimental Verification

IEEE transactions on power electronics, 2019
This paper describes a novel, model-based, and design optimization methodology for high-power medium-frequency transformers (MFTs) for medium-voltage high-power electronic applications, namely emerging solid-state transformers.
M. Mogorovic, D. Dujić
semanticscholar   +1 more source