Results 131 to 140 of about 13,118,191 (341)

pH/ROS‐Responsive Injectable Hydrogel Co‐Loaded with B7‐H3 Blocker and NETs Suppressor Boosts OSCC Synergistic Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pH/ROS‐dual‐responsive injectable hydrogel, formed by dynamic boronic ester and Schiff base crosslinking, co‐delivers enoblituzumab (B7‐H3 blocker) and Cl‐amidine (NETs suppressor). Via localized intratumoral delivery, it synergistically reprograms the immunosuppressive tumor microenvironment, overcomes T cell infiltration barriers, restores ...
Huan Li   +12 more
wiley   +1 more source

Urban design pedagogy, an interdisciplinary approach

open access: yesJournal of Design for Resilience in Architecture and Planning
Among the many possible solutions to city form, urban designers are expected to create environments with some human purpose of a social, economic, aesthetic and technical merit.
Peter C. Bosselmann
doaj   +1 more source

Students’ Public success and private breakdown?

open access: yesFORMakademisk, 2023
Design literacy becomes more essential to creating a collaborative and inclusive society. Nonetheless, students were more anxious and exhibited lower performance when design studio tutors employed the conventional master-apprentice pedagogy.
Zhengping Liow
doaj  

Creative rationality and design education: Towards a pedagogy of adventure [PDF]

open access: yes
Design education is usually based on the paradigm of innovation defined as a mere application of science. This paper aims at showing that such a point of view is the result of an intellectual perspective which has thrown techniques out of science and ...
Joelle Forest, Michel Faucheux
core  

Assessment for learning and for self-regulation [PDF]

open access: yes, 2015
Drawing on a research study of formative assessment practices in Irish schools, this paper traces the design, development and pilot of the Assessment for Learning Audit instrument (AfLAi) - a research tool for measuring teachers’ understanding and ...
Lysaght, Zita
core   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

open access: yesAdvanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang   +12 more
wiley   +1 more source

Cohort‐Scale Spatial Autocorrelation for Tumor Prediction in Mid‐Infrared Pathology and Spatial Biomarker Discovery Using MALDI Imaging Lipidomics

open access: yesAdvanced Science, EarlyView.
Computational annotation of various tissue types in heterogeneous samples such as colorectal cancer liver metastasis (CRLM) using spatial autocorrelation analysis on non‐destructive mid‐infrared (MIR) imaging data enabled correlative multimodal mass spectrometry imaging (MSI) for spatial investigation of lipid tumor marker candidates. The method can be
Miriam F. Rittel   +12 more
wiley   +1 more source

A Perspective on Interactive Theorem Provers in Physics

open access: yesAdvanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

DIGITAL: multidisciplinary and multidimensional in the classrooms [PDF]

open access: yes, 2018
In this paper our aim is to analyse and present some pedagogical paths that prefigure and guide the teaching-learning devices developed "around" the digital tools.
Nobre, Ana
core  

Closed-Loop Design Pedagogies

open access: yeshyphen
“Amid the clamor of modernity’s ceaseless march, there exists a lamentable loss, one not often heard but profoundly felt - the gradual fading of the architectural narratives that once wove the tapestry of humanity’s existence.”1  – Dionysopoulou 2017   This essay reviews the integration of closed-loop design pedagogies in the architecture curriculum at
openaire   +1 more source

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