Results 31 to 40 of about 94,066 (344)

Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats [PDF]

open access: yes, 2017
Rationale Corticostriatal circuits are widely implicated in the top-down control of attention including inhibitory control and behavioural flexibility. However, recent neurophysiological evidence also suggests a role for thalamic inputs to striatum in
A Bari   +36 more
core   +2 more sources

25C-NBOMe: preliminary data on pharmacology, psychoactive effects, and toxicity of a new potent and dangerous hallucinogenic drug [PDF]

open access: yes, 2014
Introduction. The use of novel psychoactive substances (NPSs) has rapidly increased as well as their online availability. The aim of this paper is to provide a comprehensive review of the nature and the risks associated with 25C-NBOMe, which has recently
BERSANI, FRANCESCO SAVERIO   +10 more
core   +5 more sources

Designer Drugs: A Review of Literature Abdulsallam Bakdash

open access: yesArab Journal of Forensic Sciences & Forensic Medicine, 2015
A new phenomenon in the drug market has appeared in recent years: there has been an increase in the number and types of designer drugs. A massive influx of these structural and/or functional analogs of controlled substances has resulted in an increase in
Abdulsallam Bakdash
doaj   +1 more source

“New designer drugs” in aspects of forensic toxicology

open access: yesArchives of Forensic Medicine and Criminology, 2014
Aim of the study : In autumn of 2010, in response to an ever-increasing market of “new designer drugs” and in view of new legal regulations, the Sanitary Inspection inspected numerous so-called “smart shops” where such products were sold.
Martyna Maciów-Głąb   +3 more
doaj   +1 more source

The bridge between classical and ‘synthetic’/chemical psychoses: towards a clinical, psychopathological and therapeutic perspective [PDF]

open access: yes, 2019
© 2019 Orsolini, Chiappini, Papanti, De Berardis, Corkery and Schifano. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania   +5 more
core   +2 more sources

Hazard Characterization of Synthetic Cathinones Using Viability, Monoamine Reuptake, and Neuronal Activity Assays

open access: yesFrontiers in Neuroscience, 2020
Synthetic cathinones are the second largest class of new psychoactive substances (NPS) on the drug market. Despite the large number of different cathinones and their abundant use, hazard characterization is mainly limited to their potential to inhibit ...
Anne Zwartsen   +4 more
doaj   +1 more source

Between designer drugs and afterburners: A Lexicographic-Semantic Study of Equivalence

open access: yesLexikos, 2021
The lexicons of natural languages are not isomorphic. Reasons for the anisomorphism can be sought on three interrelated planes: language structure, extralinguistic reality, and conceptualisation.
Arleta Adamska-Sałaciak
doaj   +1 more source

Rational Drug Design Paradigms: The Odyssey for Designing Better Drugs

open access: yesCombinatorial Chemistry & High Throughput Screening, 2015
Due to the time and effort requirements for the development of a new drug, and the high attrition rates associated with this developmental process, there is an intense effort by academic and industrial researchers to find novel ways for more effective drug development schemes.
Kellici T   +13 more
openaire   +4 more sources

Artykuł 160 k.k. jako (potencjalny) środek walki z niektórymi spośród społecznie niepożądanych zachowań związanych z dopalaczami

open access: yesActa Iuris Stetinensis, 2018
The goal of this work is to answer a question if the regulations of art. 160 § 1–3 k.k. could be used in combating designer drugs. The findings of this work are based on: 1) analysis of the normative materials referring to the examined issue; and – 2 ...
Konrad Burdziak
doaj   +1 more source

Clinical pattern of poisoning among patients declared as taking novel recreational drugs

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2020
Objectives Intoxication with novel psychoactive drugs poses a significant challenge for medicine due to diagnostic difficulties, complex clinical patterns resulting from the polyethiology of poisoning, and the risk of fatal complications.
Anna Krakowiak   +3 more
doaj   +1 more source

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