Results 31 to 40 of about 94,577 (347)

25C-NBOMe: preliminary data on pharmacology, psychoactive effects, and toxicity of a new potent and dangerous hallucinogenic drug [PDF]

open access: yes, 2014
Introduction. The use of novel psychoactive substances (NPSs) has rapidly increased as well as their online availability. The aim of this paper is to provide a comprehensive review of the nature and the risks associated with 25C-NBOMe, which has recently
BERSANI, FRANCESCO SAVERIO   +10 more
core   +5 more sources

The bridge between classical and ‘synthetic’/chemical psychoses: towards a clinical, psychopathological and therapeutic perspective [PDF]

open access: yes, 2019
© 2019 Orsolini, Chiappini, Papanti, De Berardis, Corkery and Schifano. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania   +5 more
core   +2 more sources

Roar of meow-meow (mephedrone) in India

open access: yesJournal of Mental Health and Human Behaviour, 2015
Recently, a dangerous new designer drug mephedrone has fast gained popularity among the youth and teens of India. Its abuse has soared to mount to an epidemic.
Pooja Yudhishthir Palkar   +1 more
doaj   +1 more source

Between designer drugs and afterburners: A Lexicographic-Semantic Study of Equivalence

open access: yesLexikos, 2021
The lexicons of natural languages are not isomorphic. Reasons for the anisomorphism can be sought on three interrelated planes: language structure, extralinguistic reality, and conceptualisation.
Arleta Adamska-Sałaciak
doaj   +1 more source

Rational Drug Design Paradigms: The Odyssey for Designing Better Drugs

open access: yesCombinatorial Chemistry & High Throughput Screening, 2015
Due to the time and effort requirements for the development of a new drug, and the high attrition rates associated with this developmental process, there is an intense effort by academic and industrial researchers to find novel ways for more effective drug development schemes.
Kellici T   +13 more
openaire   +4 more sources

High-potency ligands for DREADD imaging and activation in rodents and monkeys

open access: yesNature Communications, 2019
Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a powerful tool for neuroscience, but the standard DREADD ligand, CNO, has significant drawbacks.
Jordi Bonaventura   +24 more
doaj   +1 more source

Hazard Characterization of Synthetic Cathinones Using Viability, Monoamine Reuptake, and Neuronal Activity Assays

open access: yesFrontiers in Neuroscience, 2020
Synthetic cathinones are the second largest class of new psychoactive substances (NPS) on the drug market. Despite the large number of different cathinones and their abundant use, hazard characterization is mainly limited to their potential to inhibit ...
Anne Zwartsen   +4 more
doaj   +1 more source

Artykuł 160 k.k. jako (potencjalny) środek walki z niektórymi spośród społecznie niepożądanych zachowań związanych z dopalaczami

open access: yesActa Iuris Stetinensis, 2018
The goal of this work is to answer a question if the regulations of art. 160 § 1–3 k.k. could be used in combating designer drugs. The findings of this work are based on: 1) analysis of the normative materials referring to the examined issue; and – 2 ...
Konrad Burdziak
doaj   +1 more source

Clinical pattern of poisoning among patients declared as taking novel recreational drugs

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2020
Objectives Intoxication with novel psychoactive drugs poses a significant challenge for medicine due to diagnostic difficulties, complex clinical patterns resulting from the polyethiology of poisoning, and the risk of fatal complications.
Anna Krakowiak   +3 more
doaj   +1 more source

2-(4-IODO-2,5-DIMETOXIFENIL)-N-[(2-METOXIFENIL)METIL]ETAMINA OU 25I-NBOME: CARACTERIZAÇÃO QUÍMICA DE UMA DESIGNER DRUG

open access: yesQuímica Nova, 2016
Drug trafficking and the introduction of new drugs onto the illicit market are one of the main challenges of the forensic community. In this study, the chemical profile of a new designer drug, 2-(4-iodine-2,5-dimethoxyphenyl)-n-[(2-methoxyphenyl)methyl ...
Pâmella F. dos Santos   +11 more
doaj   +1 more source

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