Results 41 to 50 of about 94,066 (344)
High-potency ligands for DREADD imaging and activation in rodents and monkeys
Nature Communications, 2019 Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are a powerful tool for neuroscience, but the standard DREADD ligand, CNO, has significant drawbacks.
Jordi Bonaventura +24 more
doaj +1 more source
Química Nova, 2016 Drug trafficking and the introduction of new drugs onto the illicit market are one of the main challenges of the forensic community. In this study, the chemical profile of a new designer drug, 2-(4-iodine-2,5-dimethoxyphenyl)-n-[(2-methoxyphenyl)methyl ...
Pâmella F. dos Santos +11 more
doaj +1 more source
ELISA detection of phenazepam, etizolam, pyrazolam, flubromazepam, diclazepam and delorazepam in blood using Immunalysis® benzodiazepine kit [PDF]
, 2015 Phenazepam and etizolam were the first uncontrolled benzodiazepines available for sale in the UK. Pyrazolam, flubromazepam and diclazepam are not used medicinally anywhere in the world; they are produced exclusively for the uncontrolled, recreational ...
Mckeown, Denise A. +2 more
core +2 more sources
Synthetic cathinones related fatalities: an update [PDF]
, 2018 Synthetic cathinones, more commonly known as "bath salts", are synthetic drugs chemically related to cathinone, a psychostimulant found in the khat plant.
Busardò, F. P. +5 more
core +1 more source
Roar of meow-meow (mephedrone) in India
Journal of Mental Health and Human Behaviour, 2015 Recently, a dangerous new designer drug mephedrone has fast gained popularity among the youth and teens of India. Its abuse has soared to mount to an epidemic.
Pooja Yudhishthir Palkar +1 more
doaj +1 more source
Pharmacology of novel psychoactive substances [PDF]
, 2016 This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core +1 more source
Novel Designer Benzodiazepines: Comprehensive Review of Evolving Clinical and Adverse Effects
Neurology International, 2022 As tranquilizers, benzodiazepines have a wide range of clinical uses. Recently, there has been a significant rise in the number of novel psychoactive substances, including designer benzodiazepines.
Amber N. Edinoff +9 more
doaj +1 more source
Monitoring risk behaviour in adolescent pupils regarding consumption of psychoactive substances
Annals of Agricultural and Environmental Medicine, 2017 Introduction Taking psychoactive substances constitutes a significant problem for Public Health, particularly in preventing drug abuse and addiction. Objectives To estimate the amount and incidence of drug consumption in middle and high school pupils ...
Paulina Wojtyła-Buciora +8 more
doaj +1 more source
Designers Drugs—A New Challenge to Emergency Departments—An Observational Study in Poland
Medicina, 2020 Background and Objective: In the last decade, the phenomenon of using new psychoactive substances (NPS), called designer drugs, has been on rise. Though their production and marketing in Poland is prohibited, reports of the Supreme Audit Office noted ...
Rakesh Jalali +7 more
doaj +1 more source
Piperazine derivatives as dangerous abused compounds
Acta Pharmaceutica, 2020 Piperazine derivatives are a group of compounds with a psychostimulant effect. They are an alternative to illegal drugs. They are being searched for recreational use due to their psychoactive and hallucinogenic effects.
Welz Anna, Koba Marcin
doaj +1 more source