Results 21 to 30 of about 72,501 (324)
Desmin interacts with STIM1 and coordinates Ca2+ signaling in skeletal muscle
JCI Insight, 2021 Stromal interaction molecule 1 (STIM1), the sarcoplasmic reticulum (SR) transmembrane protein, activates store-operated Ca2+ entry (SOCE) in skeletal muscle and, thereby, coordinates Ca2+ homeostasis, Ca2+-dependent gene expression, and contractility ...
Hengtao Zhang +9 more
semanticscholar +1 more source
bioRxiv, 2021 In heart failure, an increased abundance of post-translationally detyrosinated microtubules stiffens the cardiomyocyte and impedes its contractile function. Detyrosination promotes interactions between microtubules, desmin intermediate filaments, and the
A. K. Salomon +6 more
semanticscholar +1 more source
Scientific Reports, 2022 Desmin is the guardian of striated muscle integrity, permitting the maintenance of muscle shape and the efficiency of contractile activity. It is also a key mediator of cell homeostasis and survival.
Charlotte Claeyssen +2 more
doaj +1 more source
Journal of Fungi, 2022 Candida albicans can cause various infections, especially in immunocompromised patients. Its ability to develop resistance to the current antifungal drugs as well as its multiple virulence factors have rendered the problem even more complicated. Thus, in
Walaa A. Negm +6 more
doaj +1 more source
Multiple sites in αB-crystallin modulate its interactions with desmin filaments assembled in vitro. [PDF]
PLoS ONE, 2011 The β3- and β8-strands and C-terminal residues 155-165 of αB-crystallin were identified by pin arrays as interaction sites for various client proteins including the intermediate filament protein desmin.
Scott A Houck +3 more
doaj +1 more source
Congenital sacrococcygeal rhabdomyosarcoma
African Journal of Paediatric Surgery, 2022 Rhabdomyosarcoma (RMS) is one of the common malignant soft-tissue sarcomas affecting children. It originates from the embryonic mesenchyme precursor of striated muscle and is frequently seen in the head-and-neck region, genitourinary system and ...
Renuka Venkata Inuganti +3 more
doaj +1 more source
Drosophila Nesprin-1 Isoforms Differentially Contribute to Muscle Function
Cells, 2021 Nesprin-1 is a large scaffold protein connecting nuclei to the actin cytoskeleton via its KASH and Calponin Homology domains, respectively. Nesprin-1 disconnection from nuclei results in altered muscle function and myonuclei mispositioning.
Alexandre Rey +3 more
doaj +1 more source
Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source
Toxins, 2022 Carboxylic ionophores, such as monensin, salinomycin and lasalocid, are polyether antibiotics used widely in production animals for the control of coccidiosis, as well as for the promotion of growth and feed efficiency.
Danielle Henn +3 more
doaj +1 more source
Spatial Fuzzy C-means dan Rapid Region Merging untuk Pemisahan Sel Kanker Payudara
Jurnal Nasional Teknik Elektro dan Teknologi Informasi, 2017 Segmentation and overlapped cells separation are important phases in microscopic image processing of breast cancer, because the accuracy of overlapped cells separation result determines the accuracy of breast cancer cell calculation. The amount of breast
Desmin Tuwohingide, Chastine Fatichah
doaj +1 more source