Results 111 to 120 of about 18,623 (291)

Autoantibodies against desmoglein 2 are not pathogenic in pemphigus

Anais Brasileiros de Dermatologia, 2022
Anti-desmoglein 1 and 3 autoantibodies justify acantholysis in pemphigus; however, the pathogenesis of anti-desmoglein 2 is hypothetical.To compare the participation of desmogleins 1, 2 and 3 through the production of serum autoantibodies, and protein and gene expression in the skin/mucosa of patients with pemphigus foliaceus and pemphigus vulgaris.The
Marcela Calixto Brandão Miguel, Tamiris Amanda Julio, Sebastian Vernal, Natália Aparecida de Paula, Andre Lieber, Ana Maria Roselino   +5 more
openaire   +4 more sources

Proteomic analysis of skin invasion by blood fluke larvae. [PDF]

, 2008
BackgroundDuring invasion of human skin by schistosome blood fluke larvae (cercariae), a multicellular organism breaches the epidermis, basement membrane, and dermal barriers of skin.
Braschi, Simon, Debnath, Moumita, Hansell, Elizabeth, Ingram, Jessica, Lim, KC, McKerrow, James H, Medzihradszky, Katalin F, Sajid, Mohammed   +7 more
core   +1 more source

Paraneoplastic pemphigus with clinical features of lichen planus associated with low-grade B cell lymphoma [PDF]

, 2005
BACKGROUND: Neoplasia-induced lichen planus is described as a cell-mediated reaction to unknown epithelial antigens. Paraneoplastic pemphigus (PNP), characterized by the presence of a specific array of autoantibodies, probably represents a different form
Black, M, Coelho, S, Figueiredo, A, Reis, JP, Tellechea, O   +4 more
core   +1 more source

Hailey‐Hailey Disease: An Updated Review With a Focus on Therapeutic Mechanisms

Health Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background Hailey‐Hailey disease (HHD), or familial benign chronic pemphigus, is a rare autosomal dominant genodermatosis characterized by chronic, painful, erythematous, erosive plaques and fissures at sites of friction such as the neck, axilla, groin, and perineum.
Mahesh Mathur, Sumit Paudel, Nabita Bhattarai, Sambidha Karki, Sandhya Regmi   +4 more
wiley   +1 more source

Desmoglein ELISA in the Diagnosis of Pemphigus and Its Correlation with the Severity of Pemphigus Vulgaris

Iranian Journal of Allergy, Asthma and Immunology, 2009
Anti-desmoglein 3 and 1 autoantibodies are involved in the pathogenesis of pemphigus diseases. Our objective was to assess the value of ELISA in the diagnosis of pemphigus and its correlation with the severity of pemphigus vulgaris.
Mortazavi Hossein, Shahdi Majid , Amirzargar Ali Akbar , S.Naraghi Zahra, Valikhani Mahin , Daneshpazhooh Maryam, Vasheghani-Farahani Amir, Sedaghat Mojtaba, Chams-Davatchi Cheyda   +8 more
doaj  

Ear, nose and throat manifestations in pemphigus vulgaris [PDF]

, 2007
Pemphigus vulgaris (PV) is an autoimmune disease characterized by mucocutaneous intraepithelial blisters and pathogenic autoantibodies against desmoglein 3. There are two clinical forms: mucosal (MPV) and mucocutaneous (MCPV).
España, A. (Agustín), Fernández-González, S. (Secundino), Marquina, M. (Miren), Olmo-López, J. (Julio) del, Pretel, M. (Maider), Ruba, D. (David), Sanchez-Ibarrola, A. (Alfonso)   +6 more
core   +1 more source

Gluten‐related skin disorders: clinical presentation, diagnostic and treatments

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 7, Page 857-867, July 2025.
Summary Gluten‐related disorders (GRDs) encompass a spectrum of clinical manifestations triggered by gluten ingestion in genetically susceptible individuals. These disorders include celiac disease (CD) and non‐celiac gluten sensitivity (NCGS) and present with both intestinal and extraintestinal symptoms, including skin manifestations.
Dario Didona, Roberto Maglie, Farzan Solimani   +2 more
wiley   +1 more source

Desmoglein autoimmunity in the pathogenesis of pemphigus

Autoimmunity, 2006
The most characteristic feature of pemphigus is a loss of cohesion between keratinocytes, resulting in formation of blisters and erosions on the mucosal membranes and the skin. Identification of circulating antibodies which bind to desmogleins (Dsg), transmembrane proteins involved in assembly of the desmosomes, led to the immediate realization that ...
openaire   +2 more sources

Striatins as plaque molecules of zonulae adhaerentes in simple epithelia, of tessellate junctions in stratified epithelia, of cardiac composite junctions and of various size classes of lateral adherens junctions in cultures of epithelia- and carcinoma-derived cells [PDF]

, 2014
Proteins of the striatin family (striatins 1–4; sizes ranging from 90 to 110 kDa on SDS-polyacrylamide gel electrophoresis) are highly homologous in their amino acid sequences but can differ in their cell-type-specific gene expression patterns and ...
Dörflinger, Yvette, Franke, Werner W., Frey, Norbert, Heid, Hans, Kuhn, Caecilia, Rickelt, Steffen, Rosin-Arbesfeld, Rina, Zimbelmann, Ralf   +7 more
core   +2 more sources

The Desmosomal Cadherin Desmoglein-2 Experiences Mechanical Tension as Demonstrated by a FRET-Based Tension Biosensor Expressed in Living Cells

Cells, 2018
Cell-cell junctions are critical structures in a number of tissues for mechanically coupling cells together, cell-to-cell signaling, and establishing a barrier. In many tissues, desmosomes are an important component of cell-cell junctions.
Sindora R. Baddam, Paul Arsenovic, Vani Narayanan, Nicole R. Duggan, Carl R. Mayer, S. T. Newman, Dahlia A Abutaleb, Abhinav Mohan, A. Kowalczyk, D. Conway   +9 more
semanticscholar   +1 more source