Results 51 to 60 of about 14,267 (224)
Frontiers in Immunology, 2023 Autoimmune blistering diseases (AIBD) are paradigms of autoantibody-mediated organ-specific autoimmune disorders that involve skin and/or mucous membranes.
Shirin Emtenani +5 more
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Frontiers in Oncology, 2021 BackgroundPemphigus vulgaris (PV) is a rare and severe autoimmune blistering disorder affecting the skin and mucous membranes, characterized by the production of autoantibodies against two desmosomal adhesion proteins, desmoglein 1 and 3.
Rosalba Buquicchio +5 more
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Alterations in hepatic miRNA expression during negative energy balance in postpartum dairy cattle [PDF]
, 2014 peer-reviewedBackground Negative energy balance (NEB), an altered metabolic state, occurs in early postpartum dairy cattle when energy demands to support lactation exceed energy intake.
Fatima, Attia +4 more
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Identification of Desmoglein as a Cadherin and Analysis of Desmoglein Domain Structure
Journal of Investigative Dermatology, 2007 In the 1980s and early 1990s, the ability to clone complementary DNA (cDNA) resulted in great advances in cell biology, including our understanding of cell adhesion. Cloning the cDNA encoding desmosomal molecules, and the determination of their deduced amino-acid sequences, provided novel insights into their structure and function. It had been shown by
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Frontiers in Immunology, 2019 Pemphigus is an autoimmune dermatosis in which mucocutaneous blisters are induced primarily by autoantibodies against Desmoglein (Dsg) 1 and 3. Pemphigus vulgaris (PV) usually is associated with autoantibodies against Dsg3 whereas pemphigus foliaceus (PF)
Elias Walter +6 more
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Evaluation of autoantibodies to desmoglein-2 in dogs with and without cardiac disease
Scientific Reports, 2023 Autoantibodies to desmoglein-2 have been associated with arrhythmogenic right ventricular cardiomyopathy (ARVC) in people. ARVC is a common disease in the Boxer dog.
Ashley L. Walker +6 more
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Cells, 2023 Pemphigus vulgaris (PV) is a potentially lethal autoimmune bullous skin disorder caused by IgG autoantibodies against desmoglein 3 (Dsg3) and Dsg1. During the last three decades, high-dose intravenous immunoglobulins (IVIgs) have been applied as an ...
Christoph Hudemann +4 more
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The mapping of linear B-cell epitope regions in desmoglein 1 and 3 proteins : Recognition of immobilized peptides by pemphigus patients’ serum autoantibodies [PDF]
, 2013 Desmosomal transmembrane glycoproteins desmoglein 1and desmoglein 3 are targets of life-threatening autoimmune blistering disorders such as Pemphigus vulgaris (PV) and Pemphigus foliaceus(PF).
Bősze, Szilvia +5 more
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Desmogleins and Desmocollins as Adhesive Molecules [PDF]
Journal of Investigative Dermatology, 2007 Following the identification of desmoglein and desmocollins as the transmembrane components of the desmosome, sequence analysis re vealed that they are members of the cadherin family of cell–cell adhesion molecules. Cadherins are characterized by the presence of conserved extracellular calcium-binding motifs.
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Desmoglein as a Target in Skin Disease and Beyond [PDF]
Journal of Investigative Dermatology, 2012 Much of the original research on desmosomes and their biochemical components was through analysis of skin and mucous membranes. The identification of desmogleins 1 and 3, desmosomal adhesion glycoproteins, as targets in pemphigus, a fatal autoimmune blistering disease of the skin and mucous membranes, provided the first link between desmosomes ...
Amagai, Masayuki, Stanley, John R.
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