Results 31 to 40 of about 14,267 (224)

Autoimmune diseases and their manifestations on oral cavity: diagnosis and clinical management [PDF]

, 2018
Oral signs are frequently the first manifestation of autoimmune diseases. For this reason, dentists play an important role in the detection of emerging autoimmune pathologies.
Bossù, Maurizio, Di Carlo, Gabriele, Giovarruscio, Francesca, Polimeni, Antonella, Saccucci, Matteo, Salucci, Alessandro   +5 more
core   +2 more sources

Electron microscopy of desmosomal structures in the pemphigus human skin organ culture model

Frontiers in Medicine, 2022
Pemphigus is a chronic autoimmune skin blistering disease, characterized by acantholysis and by the production of autoantibodies directed against the structural desmosomal proteins desmoglein 1 (DSG1) and/or DSG3.
Uta Katharina Radine, Valéria Bumiller-Bini Hoch, Valéria Bumiller-Bini Hoch, Angelica B. Winter Boldt, Detlef Zillikens, Detlef Zillikens, Ralf J. Ludwig, Ralf J. Ludwig, Ralf J. Ludwig, Christoph M. Hammers, Christoph M. Hammers, Christoph M. Hammers, Matthias Klinger, Jennifer E. Hundt, Jennifer E. Hundt   +14 more
doaj   +1 more source

Dermatology [PDF]

, 2004
Dermatology continues to develop at a steady pace. In the past few years there have been exciting advances in our understanding of skin structure and function in health and disease and progress in genetics, epidemiology, immunology, pharmacology and ...
Boffa, Michael J.
core   +1 more source

Detection of Autoantibodies against Recombinant Desmoglein 1 and 3 Molecules in Patients with Pemphigus vulgaris: Correlation with Disease Extent at the Time of Diagnosis and during Follow-Up

Clinical and Developmental Immunology, 2009
The recent availability of cDNA clones for pemphigus antigens has allowed the production of recombinant desmoglein 1 and desmoglein 3 molecules and the development of an ELISA approach in order to determine levels of antibodies to them.
Anna Belloni-Fortina, Diana Faggion, Barbara Pigozzi, Andrea Peserico, Matteo Bordignon, Vincenzo Baldo, Mauro Alaibac   +6 more
doaj   +1 more source

Pemphigus—The Crux of Clinics, Research, and Treatment during the COVID-19 Pandemic

Biomedicines, 2021
Pemphigus is a rare autoimmune disease characterised by the production of pathogenic autoantibodies in response to different desmosome proteins. The pathophysiological process leads to the development of blisters and erosions on mucosal and/or skin ...
Branka Marinović, Joško Miše, Ines Lakoš Jukić, Zrinka Bukvić Mokos   +3 more
doaj   +1 more source

Expression of the FGFR2c mesenchymal splicing variant in human keratinocytes inhibits differentiation and promotes invasion [PDF]

, 2018
The altered isoform switching of the fibroblast growth factor receptor 2 (FGFR2) and aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells is involved in cancer progression.
Anacker, Barbaresi, Barton, Belleudi, Boukamp, Brooks, Candi, Capone, Chaffer, Dotto, Feng, Gaggioli, Getsios, Goetz, Grose, Harmon, Haugsten, Ishiwata, Izar, Jones, Kawase, Matsuda, Oh, Oltean, Peng, Petiot, Pickard, Pickard, Purpura, Raffa, Ramsey, Ranieri, Ranieri, Shamir, Shih, Simpson, Truong, Turner, Warzecha, Warzecha, Yang, Ye, Zhang, Zhao   +43 more
core   +1 more source

Anti-Desmocollin Autoantibodies in Autoimmune Blistering Diseases

Frontiers in Immunology, 2021
The presence of anti-desmocollin (Dsc) antibodies is rarely described in autoimmune blistering diseases patients. Moreover, several clinical phenotypes of pemphigus may be associated with these antibodies.
Xavier Bosch-Amate, Pilar Iranzo, Marta Ivars, José Manuel Mascaró Galy, Agustín España   +4 more
doaj   +1 more source

Evaluation of Desmoglein 1 and Desmoglein 3 Autoantibodies in Oral Cancer: A Pilot Study

Journal of Indian Academy of Oral Medicine and Radiology, 2023
Background: Carcinogenesis is a complex multistep process involving alterations at the cellular level. Alteration in cell-to-cell adhesion of oral epithelium plays an important role in carcinogenesis and metastasis. The alterations in the role of desmosomal components due to autoantibodies to desmoglein 1 (DSG 1) and desmoglein
Pavan Kumar Yellarthi, Arvind Muthukrishnan, Raghurama Rao Gandikota, Y Sandhya Pavankumar, Divya Uppala   +4 more
openaire   +2 more sources

Detection of Desmoglein-3 Auto-Antibodies in Patients with Lichen Planus [PDF]

Egyptian Journal of Medical Research, 2022
There is controversy about the role of auto anti-bodies against desmoglein 3 (Dsg 3) in the pathogenesis of lichen planus (LP). The goal of this study is to detect desmoglein-3 auto-antibodies in lichen planus patients comparted to normal control persons
Abd-El Aziz El-Rifaie, Laila Rashed, Mona Abdellatif, Asmaa Mohamed   +3 more
doaj   +1 more source

Mutations in desmoglein-1 cause diverse inherited palmoplantar keratoderma phenotypes:implications for genetic screening [PDF]

, 2017
INTRODUCTION: The inherited palmoplantar keratodermas (PPKs) are a heterogeneous group of genodermatoses, characterised by thickening of the epidermis of the palms and soles. No classification system unites satisfactorily clinical presentation, pathology
Almutawa, Armstrong, Dua-Awereh, Harmon, Has, Hershkovitz, Hunt, Irvine, Itin, Keren, Klijuic, McAleer, Milingou, Nomura, Samuelov, Wan, Whittock   +16 more
core   +2 more sources