Results 21 to 30 of about 10,060 (207)

Desmoglein-3 autoantibodies in tissues of oral lichen planus patients and its correlation with disease severity: case-control study

BMC Oral Health
Background Due to the not fully understood exact pathogenesis of oral lichen planus, the patients receive symptomatic management, rather than a curative treatment.
Doaa Abdelwadood, Yasmine Ahmed Fouad, Nashwa El-Khazragy, Ahmed Elsayed Hamed Amr   +3 more
doaj   +2 more sources

ELISA detection of anti‐desmoglein 1 and anti‐desmoglein 3 and indirect immunofluorescence in oral pemphigus: A retrospective study

, 2022
Objective The aim of this study was to test the efficacy of autoantibodies to desmoglein 1 and desmoglein 3 detected by ELISA and indirect immunofluorescence in the diagnosis of oral pemphigus and to correlate the antibody titres with the severity of ...
Contaldo, Maria, Dorina Lauritano, Petruzzi, Massimo, Alberta Lucchese, Della Vella, Fedora, Massimo Petruzzi, Tampoia, Marilina, Marilina Tampoia, Frassanito, Maria Antonia, Maria Antonia Frassanito, Antonia Frassanito, Maria, Lauritano, Dorina, Lucchese, Alberta, Maria Contaldo, Fedora della Vella   +14 more
core   +2 more sources

The Desmosome-Keratin Scaffold Integrates ErbB Family and Mechanical Signaling to Polarize Epidermal Structure and Function

Frontiers in Cell and Developmental Biology, 2022
While classic cadherin-actin connections in adherens junctions (AJs) have ancient origins, intermediate filament (IF) linkages with desmosomal cadherins arose in vertebrate organisms.
Kathleen J. Green, Kathleen J. Green, Kathleen J. Green, Carien M. Niessen, Carien M. Niessen, Carien M. Niessen, Matthias Rübsam, Matthias Rübsam, Matthias Rübsam, Bethany E. Perez White, Bethany E. Perez White, Joshua A. Broussard, Joshua A. Broussard, Joshua A. Broussard   +13 more
doaj   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Detection of anti-desmoglein antibodies in oral lichen planus: What do we know so far

Frontiers in Immunology, 2022
Oral lichen planus (OLP) is an inflammatory disease of the oral mucosa. Clinically, two main subsets are described, namely non-erosive and erosive OLP. While non-erosive OLP is usually responsive to local therapies, erosive OLP is often refractory also ...
Dario Didona, Michael Hertl
doaj   +1 more source

Paraneoplastic Pemphigus Autoantibodies Against C-terminus of Desmoplakin Induced Acantholysis In Vitro and In Vivo

Frontiers in Immunology, 2022
Paraneoplastic pemphigus (PNP) is an autoimmune bullous disease associated with underlying neoplasms and characterized by antibodies against desmoglein 3 (Dsg 3) and plakins.
Xue Wang, Xue Wang, Xue Wang, Xue Wang, Rui Wang, Rui Wang, Rui Wang, Dingfang Bu, Leyi Wang, Leyi Wang, Leyi Wang, Yuexin Zhang, Yuexin Zhang, Yuexin Zhang, Yuan Chang, Yuan Chang, Yuan Chang, Chenyang Zhang, Chenyang Zhang, Xixue Chen, Xixue Chen, Xixue Chen, Xuejun Zhu, Xuejun Zhu, Xuejun Zhu, Zhi Liu, Mingyue Wang, Mingyue Wang, Mingyue Wang   +28 more
doaj   +1 more source

The pemphigus monoclonal antibody clone P5G6 (AX353) retains cell-surface staining by immunofluorescence and desmoglein binding by ELISA in an engineered scFv-Fc format

Antibody Reports, 2022
The recombinant human antibody clone P5G6 (AX353) in an engineered scFv-Fc format detects by immunofluorescence cell-surface proteins on cryosections of monkey esophagus.
Christoph M. Hammers, Jens Wrammert
doaj   +1 more source

A Case Report of a Patient With Recalcitrant Pemphigus Vulgaris Treated With Rituximab. [PDF]

Clin Case Rep
ABSTRACT Pemphigus vulgaris may demonstrate differential treatment responses across disease sites. In this case, cutaneous lesions responded to high‐dose corticosteroids, whereas refractory oral disease required rituximab to achieve remission, highlighting the need for individualized, multimodal therapy to achieve sustained disease control.
Kgokolo MC, Nevondo LM, Beetge M, Khammissa RAG.   +3 more
europepmc   +2 more sources

Dsg1 and Dsg3 Composition of Desmosomes Across Human Epidermis and Alterations in Pemphigus Vulgaris Patient Skin

Frontiers in Immunology, 2022
Desmosomes are important epidermal adhesion units and signalling hubs, which play an important role in pemphigus pathogenesis. Different expression patterns of the pemphigus autoantigens desmoglein (Dsg)1 and Dsg3 across different epidermal layers have ...
Thomas Schmitt, Julia Pircher, Letyfee Steinert, Katharina Meier, Kamran Ghoreschi, Franziska Vielmuth, Daniela Kugelmann, Jens Waschke   +7 more
doaj   +1 more source

Staphylococcal Exfoliative Toxin B Specifically Cleaves Desmoglein 1 [PDF]

, 2002
Staphylococcal scalded skin syndrome and its localized form, bullous impetigo, show superficial epidermal blister formation caused by exfoliative toxin A or B produced by Staphylococcus aureus.
Stanley, John R., Takayuki Yamaguchi, John R. Stanley, Nishifuji, Koji, Masayuki Amagai, Yamaguchi, Takayuki, Hanakawa, Yasushi, Yasushi Hanakawa, Amagai, Masayuki, Motoyuki Sugai, Sugai, Motoyuki, Koji Nishifuji   +11 more
core   +1 more source