Results 211 to 220 of about 23,741,217 (251)
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Multiple facets of desmoglein 1 mutations
British Journal of Dermatology, 20181 Lanternier F, Pathan S, Vincent QB et al. Deep dermatophytosis and inherited CARD9 deficiency. N Engl J Med 2013; 369:1704–14. 2 Farmand S, Sundin M. Hyper-IgE syndromes: recent advances in pathogenesis, diagnostics and clinical care. Curr Opin Hematol
C. Has
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Veterinary dermatology (Print), 2022
BACKGROUND Canine trunk-dominant pemphigus foliaceus (PF) is mentioned rarely in the literature. HYPOTHESIS/OBJECTIVES The goal of this study was to provide clinical description of trunk-dominant PF and to demonstrate the prevalence of serum ...
P. Bizikova, K. Linder, L. Mamo
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BACKGROUND Canine trunk-dominant pemphigus foliaceus (PF) is mentioned rarely in the literature. HYPOTHESIS/OBJECTIVES The goal of this study was to provide clinical description of trunk-dominant PF and to demonstrate the prevalence of serum ...
P. Bizikova, K. Linder, L. Mamo
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Journal of the European Academy of Dermatology and Venereology, 2022
Desmocollins (Dsc) and desmogleins (Dsg) are desmosomal cadherins that play important roles in keratinocyte cell adhesion. Autoantibodies targeting Dsc have been recently identified in several cases of pemphigus, in particular, paraneoplastic pemphigus ...
K. Kosaka +8 more
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Desmocollins (Dsc) and desmogleins (Dsg) are desmosomal cadherins that play important roles in keratinocyte cell adhesion. Autoantibodies targeting Dsc have been recently identified in several cases of pemphigus, in particular, paraneoplastic pemphigus ...
K. Kosaka +8 more
semanticscholar +1 more source
Immunolocalisation of desmoglein-1 in equine muzzle skin
Equine Veterinary Journal, 2010Desmogleins (Dsgs) are glycoproteins of the cadherin family that allow the formation of desmosomes via a Ca2+-dependent homophilic interaction. Desmosomes are cell-cell adhesion systems that contribute to the mechanical integrity of epidermis by linking to keratin intermediate filaments and, therefore, connecting the cytoskeleton of adjacent ...
MIRAGLIOTTA, VINCENZO +6 more
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Journal of Cellular Physiology, 2006
AbstractThe complexity of pemphigus acantholysis together with the weak expression of desmoglein 1 (Dsg1) in cultured keratinocytes have made the study on the pathogenic action of anti‐Dsg1 antibodies quite difficult. The pathophysiology of the acantholytic phenomenon could depend on the reduction of Dsg1 adhesion function occurring after its massive ...
CIRILLO N, GOMBOS F, LANZA, Alessandro
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AbstractThe complexity of pemphigus acantholysis together with the weak expression of desmoglein 1 (Dsg1) in cultured keratinocytes have made the study on the pathogenic action of anti‐Dsg1 antibodies quite difficult. The pathophysiology of the acantholytic phenomenon could depend on the reduction of Dsg1 adhesion function occurring after its massive ...
CIRILLO N, GOMBOS F, LANZA, Alessandro
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Targetting of desmoglein 1 in inherited and acquired skin diseases
Clinical and Experimental Dermatology, 2003Desmoglein 1 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. The desmoglein 1 gene (DSG1) is centromeric to the desmoglein gene cluster and spans approximately 45 kb of 18q12, comprising 15 exons. The transcript encodes a precursor protein of 1049 amino acids that is cleaved to yield a mature protein of ...
C. Bower, N. V. Whittock
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Pemphigus herpetiformis with IgG autoantibodies to desmoglein 1 and desmocollin 1
British Journal of Dermatology, 2015 open
H. On, T. Hashimoto, S. Kim
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Split stories converge at desmoglein 1.
Nature Medicine, 2000The exact mechanism by which exfoliative toxin A (ETA), producedby Staphylococcal aureus, causes epidermal blistering has been elusive.A combined knowledge of the pathogenesis of pemphigus, cell adhesion mechanisms,and the amino acid sequence of ETA led to a simple answer (pages 1275–1277 ).
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Autoantibodies to desmogleins 1 and 3 in patients with lichen planus
Archives of Dermatological Research, 2017There is controversy about the role of autoantibodies against desmoglein 1 and 3 (Dsg1 and 3) in the pathogenesis of lichen planus (LP); the authors planned this study to determine the presence of circulating levels of these antibodies in patients with different types of oral LP and to compare that with cutaneous LP and healthy controls.
Ghaedi Forugh +3 more
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