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Anti‐Desmoglein 3 Avidity Correlates Better With Pemphigus Vulgaris Severity Than Anti‐Desmoglein 3 Concentration

International Journal of Dermatology
ABSTRACT Background Pemphigus vulgaris (PV) is caused by immunoglobulin G (IgG) autoantibodies targeting desmoglein 3 (Dsg3) and/or desmoglein 1 (Dsg1). While antibody concentration is routinely used to assess disease activity, the role of antibody avidity in PV monitoring has not been ...
Branislav Lekic   +5 more
openaire   +2 more sources

Desmoglein 3 and 1 in desquamative gingivitis

2003
Evaluation of dsg 3 and 1 autoantibodies may play an important role in the desquamative gingivitis.
Brozović-Sistig, Suzana   +3 more
openaire   +1 more source

AUTOANTIBODIES TO DESMOGLEIN‑3 IN PATIENTS WITH ACANTHOLYTIC PEMPHIGUS

Dermatology and Venerology
Introduction. Current data on the pathogenesis of acantholytic pemphigus emphasize the important role of desmoglein 3 (Dsg 3) in the initiation of the autoimmune process and the formation of the clinical phenotype of the disease. The aim is to determine the level of circulating antibodies to Dsg3 in patients with different clinical forms of pemphigus ...
Kutasevych Ya.F.   +5 more
openaire   +1 more source

Desmoglein 1 and desmoglein 3 as autoimmune target of herpetiform pemphigus

Journal of Dermatological Science, 1998
Ken Ishii   +6 more
openaire   +1 more source

[Desmoglein 1-negative, desmoglein 3-positive pemphigus herpetiformis with involvement of oral mucous membranes].

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2006
A 46-year-old woman presented with a two year history of pruritic erythematous plaques with blisters, as well as oral erosions. Even though the cutaneous lesions fit best with dermatitis herpetiformis, bullous pemphigoid or pemphigoid gestationis, the histologic examination revealed eosinophilic spongiosis, most compatible with some form of pemphigus ...
Corinna, Brod   +5 more
openaire   +1 more source

Loss of correlation between intensities of desmoglein 2 and desmoglein 3 expression in basal cell carcinomas.

Acta dermatovenerologica Croatica : ADC, 2012
Desmosomal cadherins in humans involve three isoforms, each in two splicing variants, of desmocollin (DSC1-3) and four isoforms of desmoglein (DSG1-4). DSGs are transmembranous desmosomal adhesive glycoproteins, which are generally expressed in a differentiation-specific manner.
Justyna, Gornowicz-Porowska   +4 more
openaire   +1 more source

A Novel In Vivo Active Pemphigus Model Targeting Desmoglein1 and Desmoglein3: A Tool Representing All Pemphigus Variants

Biology, 2023
Emma Dorotea Zanfi   +2 more
exaly  

Influence of intravenous immunoglobulin therapy on autoantibody titers to desmoglein 3 and desmoglein 1 in pemphigus vulgaris.

European journal of dermatology : EJD, 2003
Pemphigus vulgaris (PV) is an autoimmune mucocutaneous blistering disease. Recently, patients with mucosal involvement have been described to have autoantibodies to desmoglein 3 (dsg), while patients with mucocutaneous disease have autoantibodies to dsg 1 and dsg 3.
Naveed, Sami   +2 more
openaire   +1 more source

IgA pemphigus reacting exclusively to desmoglein 3.

European journal of dermatology : EJD, 2010
IgA pemphigus is a rare disease which is classified into two major types: subcorneal pustular dermatosis (SPD) and intraepidermal neutrophilic IgA dermatosis (IEN). The autoantigen of the SPD type was identified as desmocollin1 (Dsc1), while the antigen of the IEN type is still unknown.
Mami, Tajima   +5 more
openaire   +1 more source

Desmoglein 3

2000
Clare M. Isacke, Michael A. Horton
openaire   +1 more source

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