Results 71 to 80 of about 32,522 (291)
Vaccines, 2022 Pemphigus vulgaris (PV) is a chronic, life-altering autoimmune disease due to the production of anti-desmoglein antibodies causing the loss of cell–cell adhesion in keratinocytes (acantholysis) and blister formation in both skin and mucous membranes. The
Morna F. Schmidt +4 more
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, 2004 Dermatology continues to develop at a steady pace. In the past few years there have been exciting advances in our understanding of skin structure and function in health and disease and progress in genetics, epidemiology, immunology, pharmacology and ...
Boffa, Michael J.
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Desmosomes and Intermediate Filaments: Their Consequences for Tissue Mechanics.
Cold Spring Harbor Perspectives in Biology, 2017 Adherens junctions (AJs) and desmosomes connect the actin and keratin filament networks of adjacent cells into a mechanical unit. Whereas AJs function in mechanosensing and in transducing mechanical forces between the plasma membrane and the actomyosin ...
M. Hatzfeld, René Keil, T. Magin
semanticscholar +1 more source
Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling [PDF]
, 2012 The functions of many organs depend on the generation of an epithelium. The transition from a set of loosely connected nonpolarized cells to organized sheets of closely associated polarized epithelial cells requires the assembly of specialized cell ...
Pieters, Tim +2 more
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Nomenclature of the desmosomal cadherins. [PDF]
The Journal of cell biology, 1993 Steinberg~§ * Laboratory of Eukaryotic Molecular Genetics, National Institute for Medical Research, Mill Hill, London NW7 1AA, United Kingdom; ~New York University Medical Center, School of Medicine, New York University, New York 10016; §Institut fiir Zell- und Tumorbiologie, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, Postfach 10 19 49,
BUXTON, RS +10 more
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Bidirectional regulation of desmosome hyperadhesion by keratin isotypes and desmosomal components
Cellular and Molecular Life Sciences, 2022 AbstractDesmosomes are intercellular junctions which mediate cohesion and communication in tissues exposed to mechanical strain by tethering the intermediate filament cytoskeleton to the plasma membrane. While mature desmosomes are characterized by a hyperadhesive, Ca2+-independent state, they transiently loose this state during wound healing ...
Fanny Büchau +3 more
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Российский кардиологический журнал, 2021 Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a hereditary myocardial disease with a high risk of sudden cardiac death. The most common genetic forms of the disease are associated with desmosomal gene mutations.Aim. To study the prevalence of
A. G. Shestak +4 more
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Expression of desmosomal proteins and their implications during enamel organ morphogenesis
Indian Journal of Dental Sciences, 2018 Background/Objective: The present article is between the fewest that describe the expression of desmosomal proteins in human tooth organ and to implicate desmosome and its components in tooth morphogenesis.
Hadi BILAL
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Scientific Reports, 2016 FAM83H is essential for the formation of dental enamel because a mutation in the FAM83H gene causes amelogenesis imperfecta (AI). We previously reported that the overexpression of FAM83H often occurs and disorganizes the keratin cytoskeleton in ...
T. Kuga +11 more
semanticscholar +1 more source
Frontiers in Immunology, 2018 The serological diagnosis of pemphigus relies on the detection of IgG autoantibodies directed against the epithelial cell surface by indirect immunofluorescence (IIF) on monkey esophagus and against desmoglein 1 (Dsg1) and Dsg3 by ELISA.
Federica Giurdanella +4 more
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