Results 51 to 60 of about 15,816 (206)

Desmosomes in the testis

, 2011
Desmosomes are cell-cell junctions that link to cytoplasmic intermediate filaments, and they are known to mediate robust and stable adhesion in organs such as the skin and heart.
Dolores D. Mruk, C. Yan Cheng, Cheng, C. Yan, Mruk, Dolores D.   +3 more
core   +1 more source

Incorporation of desmocollin‐2 into the plasma membrane requires N‐glycosylation at multiple sites

FEBS Open Bio, 2019
Desmocollin‐2 (DSC2) is a desmosomal protein of the cadherin family. Desmosomes are multiprotein complexes, which are involved in cell adhesion of cardiomyocytes and of keratinocytes.
Andreas Brodehl, Caroline Stanasiuk, Dario Anselmetti, Jan Gummert, Hendrik Milting   +4 more
doaj   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

Advanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu, Ruotong Li, Xiaoyue Zhang, Dandan Chen, Jianmeng Yang, Mengmeng Li, Yuhan Yin, Ya Wang, Yuqiu Tian, Haoling Yan, Dan Cui, Jiangping Song, Gaoliang Ouyang   +12 more
wiley   +1 more source

Structure and regulation of desmosomes in intercalated discs: Lessons from epithelia [PDF]

, 2022
For electromechanical coupling of cardiomyocytes, intercalated discs (ICDs) are pivotal as highly specialized intercellular contact areas. ICD consists of adhesive contacts, such as desmosomes and adherens junctions (AJs) that are partially intermingled ...
Sunil Yeruva, Jens Waschke, Waschke, Jens, Yeruva, Sunil   +3 more
core   +1 more source

Alpha-1 antitrypsin promotes re-epithelialization by regulating inflammation and migration

Frontiers in Immunology
PurposeRegulation of inflammation and re-epithelialization are critical for efficient wound healing. This study explores the role of human α1-antitrypsin (hAAT), an immunomodulatory protein, in modulating inflammation and promoting re-epithelialization ...
Idan Farber, Idan Farber, Muhammad Wated, Ronen Schuster, Lihie Sheffer, Yuval Anav, Navit Ogen-Shtern, Navit Ogen-Shtern, Alexandra Tsitrina, Diya Tacruri, Anna Bunin, Noah Benjamin Nagar, Maayan Hagbi Bal, Tomer Eliyahu, Dor Halpern, Dor Halpern, Boris Knyazer, Samuel Cohen, Sabri El-Saied, Eli C. Lewis, Eldad Silberstein, Erez Tsumi   +21 more
doaj   +1 more source

The Desmin Mutation DES-c.735G>C Causes Severe Restrictive Cardiomyopathy by Inducing In-Frame Skipping of Exon-3

Biomedicines, 2021
Currently, little is known about the genetic background of restrictive cardiomyopathy (RCM). Herein, we screened an index patient with RCM in combination with atrial fibrillation using a next generation sequencing (NGS) approach and identified the ...
Andreas Brodehl, Carsten Hain, Franziska Flottmann, Sandra Ratnavadivel, Anna Gaertner, Bärbel Klauke, Jörn Kalinowski, Hermann Körperich, Jan Gummert, Lech Paluszkiewicz, Marcus-André Deutsch, Hendrik Milting   +11 more
doaj   +1 more source

Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods

Advanced NanoBiomed Research, EarlyView.
Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria, Amy Gelmi, Peter C. Sherrell, Stefan Di Medio, Nhiem Tran, Kate Fox   +5 more
wiley   +1 more source

The desmosome and pemphigus

Histochemistry and Cell Biology, 2008
Desmosomes are patch-like intercellular adhering junctions ("maculae adherentes"), which, in concert with the related adherens junctions, provide the mechanical strength to intercellular adhesion. Therefore, it is not surprising that desmosomes are abundant in tissues subjected to significant mechanical stress such as stratified epithelia and ...
openaire   +2 more sources

Morphophysiological dynamics of the proximal post‐testicular ducts in Crotalus durissus Linnaeus, 1758 (Squamata: Viperidae)

The Anatomical Record, EarlyView.
Abstract The organization and function of reptilian excurrent ducts remain poorly characterized, particularly in Neotropical snakes. We provide the first integrative morphological, histochemical, immunohistochemical, and ultrastructural analysis of the proximal post‐testicular ducts of Crotalus durissus across reproductive stages.
Flávia Cappuccio de Resende, Gustavo Caldeira Cotta, Clara d' Ávila Fonseca Paiva de Paula Freitas, Leonardo Carvalho, Heloísa Helena Marques Oliveira, Victória Gomes Carvalho Silva, Lívia de Fátima Moreira Silva, Luciana Maria Silva, Samyra Maria dos Santos Nassif Lacerda, Guilherme Mattos Jardim Costa   +9 more
wiley   +1 more source

Desmosomes [PDF]

Current Biology, 2011
Dubash, Adi D., Green, Kathleen J.
  +5 more sources