Results 31 to 40 of about 14,857 (218)
Structure and regulation of desmosomes in intercalated discs: Lessons from epithelia [PDF]
, 2022 For electromechanical coupling of cardiomyocytes, intercalated discs (ICDs) are pivotal as highly specialized intercellular contact areas. ICD consists of adhesive contacts, such as desmosomes and adherens junctions (AJs) that are partially intermingled ...
Sunil Yeruva +3 more
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The Journal of Cell Biology, 1970 During the pupal stage of moths, a mass of connective tissue develops on the dorsal side of the abdominal nerve cord . The cells, which secrete the fibrous matrix, are originally close together, but as they secrete the matrix, they are pushed apart, with a corresponding decrease in their size .
openaire +2 more sources
Desmosomal Junctions and Connexin-43 Remodeling in High-Pacing-Induced Heart Failure Dogs
Anatolian Journal of Cardiology, 2023 Background: While desmosomal junctions and gap junction remodeling are among the arrhythmogenic substrates, the fate of desmosomal and gap junctions in high-pacing-induced heart failure remains unclear. This aim of this study was to determine the fate of
Qing Wang +6 more
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Frontiers in Pharmacology, 2022 According to the World Health Organization, the neoplasm is one of the main reasons for morbidity and mortality worldwide. At the same time, application of cytostatic drugs like an independent type of cancer treatment and in combination with surgical ...
Ekaterina Podyacheva, Yana Toropova
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Frontiers in Oncology, 2021 Typical carcinoids (TC), atypical carcinoids (AC), large cell neuroendocrine carcinomas (LCNEC), and small cell lung carcinomas (SCLC) encompass a bimodal spectrum of metastatic tumors with morphological, histological and histogenesis differences, The ...
Tabatha Gutierrez Prieto +13 more
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Role of PKC and ERK Signaling in Epidermal Blistering and Desmosome Regulation in Pemphigus
Frontiers in Immunology, 2019 Desmosomes reinforce cohesion of epithelial cells at the interface between adjacent cells. They include the cadherin-type adhesion molecules desmoglein 1 (Dsg1) and Dsg3.
Desalegn Tadesse Egu +2 more
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Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes [PDF]
Journal of Cell Biology, 2011 The desmosomal cadherins, desmogleins (Dsgs) and desmocollins (Dscs), comprise the adhesive core of intercellular junctions known as desmosomes. Although these adhesion molecules are known to be critical for tissue integrity, mechanisms that coordinate their trafficking into intercellular junctions to regulate their proper ratio and distribution are ...
Nekrasova, Oxana E. +5 more
openaire +4 more sources
Molecular force measurements in desmosomes [PDF]
, 2018 Desmosomes are cell–cell adhesion sites especially important in heart and skin tissues. Both tissues are exposed to mechanical stress and desmosomes are essential for stable cell–cell adhesion but whether and how forces act on desmosomes was unclear ...
Cost, A., Cost, Anna-Lena
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Life, 2022 The Hippo-YAP pathway serves as a central signalling hub in epithelial tissue generation and homeostasis. Yes-associated protein (YAP) is an essential downstream transcription cofactor of this pathway, with its activity being negatively regulated by ...
Yunying Huang +4 more
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Desmin variants: Trigger for cardiac arrhythmias?
Frontiers in Cell and Developmental Biology, 2022 Desmin (DES) is a classical type III intermediate filament protein encoded by the DES gene. Desmin is abundantly expressed in cardiac, skeletal, and smooth muscle cells.
Wei Su +5 more
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