Results 31 to 40 of about 15,816 (206)
Cheek-Pro-Heart: What Can the Buccal Mucosa Do for Arrhythmogenic Cardiomyopathy?
Biomedicines, 2023 Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease associated with ventricular arrhythmias and a high risk of sudden cardiac death (SCD). Although the disease was described over 40 years ago, its diagnosis is still difficult.
Carlos Bueno-Beti, Angeliki Asimaki
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New insights into desmosome regulation and pemphigus blistering as a desmosome-remodeling disease
Kaohsiung Journal of Medical Sciences, 2013 Desmosomes in keratinocytes are the most important intercellular adhering junctions that provide structural strength for the epidermis. These junctions are connected directly with desmosomal cadherin proteins.
Yasuo Kitajima
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A Monoclonal Antibody Recognizing Desmosomes: Use in Human Pathology [PDF]
, 1985 A mouse monoclonal IgG1 antibody that recognizes desmosomes in human tissues has been isolated and characterized. DP1 recognizes desmoplakin I (250 kD) in immunoblots of partially purified desmosome preparations.
Weber, Klaus +3 more
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Histopathological Features and Protein Markers of Arrhythmogenic Cardiomyopathy
Frontiers in Cardiovascular Medicine, 2021 Arrhythmogenic cardiomyopathy (ACM) is a heritable heart muscle disease characterized by syncope, palpitations, ventricular arrhythmias and sudden cardiac death (SCD) especially in young individuals.
Carlos Bueno-Beti, Angeliki Asimaki
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The Journal of Cell Biology, 1970 During the pupal stage of moths, a mass of connective tissue develops on the dorsal side of the abdominal nerve cord . The cells, which secrete the fibrous matrix, are originally close together, but as they secrete the matrix, they are pushed apart, with a corresponding decrease in their size .
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Dsg3 epitope-specific signalling in pemphigus
Frontiers in Immunology, 2023 IntroductionPemphigus is an autoantibody driven disease that impairs the barrier function of the skin and mucosa by disrupting desmosomes and thereby impeding cellular cohesion. It is known that the different clinical phenotypes of pemphigus vulgaris (PV)
Thomas Schmitt +5 more
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Expression and Significance of Cadherins and Its Subtypes in Development and Progression of Oral Cancers: A Review [PDF]
Journal of Clinical and Diagnostic Research, 2015 Cadherins are a family of transmembranous glycoproteins responsible for calcium-dependent intercellular adhesion. Absence or loss of function of E-cadherin leads to the disappearance of epithelial characteristics of the cells and generates higher ...
Yogesh Chand Rajwar +5 more
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Frontiers in Pharmacology, 2022 According to the World Health Organization, the neoplasm is one of the main reasons for morbidity and mortality worldwide. At the same time, application of cytostatic drugs like an independent type of cancer treatment and in combination with surgical ...
Ekaterina Podyacheva, Yana Toropova
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Frontiers in Oncology, 2021 Typical carcinoids (TC), atypical carcinoids (AC), large cell neuroendocrine carcinomas (LCNEC), and small cell lung carcinomas (SCLC) encompass a bimodal spectrum of metastatic tumors with morphological, histological and histogenesis differences, The ...
Tabatha Gutierrez Prieto +13 more
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Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes [PDF]
Journal of Cell Biology, 2011 The desmosomal cadherins, desmogleins (Dsgs) and desmocollins (Dscs), comprise the adhesive core of intercellular junctions known as desmosomes. Although these adhesion molecules are known to be critical for tissue integrity, mechanisms that coordinate their trafficking into intercellular junctions to regulate their proper ratio and distribution are ...
Nekrasova, Oxana E. +5 more
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