Results 11 to 20 of about 12,991 (180)
Dermatology Research and Practice, 2010 The structure, function, and regulation of desmosomal adhesion in vivo are discussed. Most desmosomes in tissues exhibit calcium-independent adhesion, which is strongly adhesive or “hyperadhesive”. This is fundamental to tissue strength.
David Garrod
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Cold Spring Harbor Perspectives in Biology, 2009 Desmosomes are intercellular junctions that tether intermediate filaments to the plasma membrane. Desmogleins and desmocollins, members of the cadherin superfamily, mediate adhesion at desmosomes. Cytoplasmic components of the desmosome associate with the desmosomal cadherin tails through a series of protein interactions, which serve to recruit ...
Emmanuella, Delva +2 more
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Journal of Cell Science, 2009 Desmosomes are one of four intercellular junctions present on the lateral side of neighboring polarized epithelial cells. Tight junctions and adherens junctions (AJs) are restricted to the apical domain, where they form the epithelial barrier and organize cortical actin, respectively.
Bhushan V, Desai +2 more
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Assembly of Desmosomal Cadherins into Desmosomes is Isoform Dependent [PDF]
Journal of Investigative Dermatology, 2001 Desmosomes are intercellular adhesive junctions that exhibit cell- and differentiation-specific differences in their molecular composition. In complex epithelia, desmosomes contain multiple representatives of the desmosomal cadherin family, which includes three desmogleins and three desmocollins.
Ishii, Ken +5 more
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Biology, 2020 Tumor resistance to therapy is associated with the 3D organization and peculiarities of the tumor microenvironment, of which intercellular adhesion is a key participant. In this work, the abundance of contact proteins was compared in SKOV-3 and SKOV-3.ip
Olga M. Kutova +6 more
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Desmosomal Junctions and Connexin-43 Remodeling in High-Pacing-Induced Heart Failure Dogs
Anatolian Journal of Cardiology, 2023 Background: While desmosomal junctions and gap junction remodeling are among the arrhythmogenic substrates, the fate of desmosomal and gap junctions in high-pacing-induced heart failure remains unclear. This aim of this study was to determine the fate of
Qing Wang +6 more
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Genetic Animal Models for Arrhythmogenic Cardiomyopathy
Frontiers in Physiology, 2020 Arrhythmogenic cardiomyopathy has been clinically defined since the 1980s and causes right or biventricular cardiomyopathy associated with ventricular arrhythmia.
Brenda Gerull +2 more
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Paradoxical Roles of Desmosomal Components in Head and Neck Cancer
Biomolecules, 2021 Desmosomes are intercellular adhesion complexes involved in various aspects of epithelial pathophysiology, including tissue homeostasis, morphogenesis, and disease development.
Yin-Qiao Liu +3 more
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Implications of normal and disordered remodeling dynamics of corneodesmosomes in stratum corneum
Dermatologica Sinica, 2015 Desmosomes and corneodesmosomes are the most important adhering junctions, providing strength for the epidermal sheet structure made of living keratinocytes and enucleated stratum corneum corneocytes, respectively.
Yasuo Kitajima
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Pervanadate stabilizes desmosomes [PDF]
Cell Adhesion & Migration, 2008 Desmosomes are intercellular junctions responsible for strong cell-cell adhesion in epithelia and cardiac muscle. Numerous studies have shown that the other major type of epithelial cell adhesion, the adherens junction, is destabilized by src-induced tyrosine phosphorylation of two of its principal components, E-cadherin and beta-catenin.
Garrod, D. +3 more
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