Results 21 to 30 of about 12,991 (180)
Cells, 2018 Cell-cell junctions are critical structures in a number of tissues for mechanically coupling cells together, cell-to-cell signaling, and establishing a barrier. In many tissues, desmosomes are an important component of cell-cell junctions.
Sindora R. Baddam +9 more
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Cheek-Pro-Heart: What Can the Buccal Mucosa Do for Arrhythmogenic Cardiomyopathy?
Biomedicines, 2023 Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease associated with ventricular arrhythmias and a high risk of sudden cardiac death (SCD). Although the disease was described over 40 years ago, its diagnosis is still difficult.
Carlos Bueno-Beti, Angeliki Asimaki
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New insights into desmosome regulation and pemphigus blistering as a desmosome-remodeling disease
Kaohsiung Journal of Medical Sciences, 2013 Desmosomes in keratinocytes are the most important intercellular adhering junctions that provide structural strength for the epidermis. These junctions are connected directly with desmosomal cadherin proteins.
Yasuo Kitajima
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Desmosomes in Developing Human Epidermis
Dermatology Research and Practice, 2010 Desmosomes play important roles in the cell differentiation and morphogenesis of tissues. Studies on animal models have greatly increased our knowledge on epidermal development while reports on human developing skin are rare due to the difficult ...
Sirkku Peltonen +2 more
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Histopathological Features and Protein Markers of Arrhythmogenic Cardiomyopathy
Frontiers in Cardiovascular Medicine, 2021 Arrhythmogenic cardiomyopathy (ACM) is a heritable heart muscle disease characterized by syncope, palpitations, ventricular arrhythmias and sudden cardiac death (SCD) especially in young individuals.
Carlos Bueno-Beti, Angeliki Asimaki
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The Journal of Cell Biology, 1970 During the pupal stage of moths, a mass of connective tissue develops on the dorsal side of the abdominal nerve cord . The cells, which secrete the fibrous matrix, are originally close together, but as they secrete the matrix, they are pushed apart, with a corresponding decrease in their size .
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Dsg3 epitope-specific signalling in pemphigus
Frontiers in Immunology, 2023 IntroductionPemphigus is an autoantibody driven disease that impairs the barrier function of the skin and mucosa by disrupting desmosomes and thereby impeding cellular cohesion. It is known that the different clinical phenotypes of pemphigus vulgaris (PV)
Thomas Schmitt +5 more
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Expression and Significance of Cadherins and Its Subtypes in Development and Progression of Oral Cancers: A Review [PDF]
Journal of Clinical and Diagnostic Research, 2015 Cadherins are a family of transmembranous glycoproteins responsible for calcium-dependent intercellular adhesion. Absence or loss of function of E-cadherin leads to the disappearance of epithelial characteristics of the cells and generates higher ...
Yogesh Chand Rajwar +5 more
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Frontiers in Pharmacology, 2022 According to the World Health Organization, the neoplasm is one of the main reasons for morbidity and mortality worldwide. At the same time, application of cytostatic drugs like an independent type of cancer treatment and in combination with surgical ...
Ekaterina Podyacheva, Yana Toropova
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Frontiers in Oncology, 2021 Typical carcinoids (TC), atypical carcinoids (AC), large cell neuroendocrine carcinomas (LCNEC), and small cell lung carcinomas (SCLC) encompass a bimodal spectrum of metastatic tumors with morphological, histological and histogenesis differences, The ...
Tabatha Gutierrez Prieto +13 more
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