Results 81 to 90 of about 14,857 (218)

Expression of desmosomal proteins and their implications during enamel organ morphogenesis

open access: yesIndian Journal of Dental Sciences, 2018
Background/Objective: The present article is between the fewest that describe the expression of desmosomal proteins in human tooth organ and to implicate desmosome and its components in tooth morphogenesis.
Hadi BILAL
doaj   +1 more source

Persistent Erythrocytosis in a Dog With a Spinal Sclerosing Paraganglioma

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT A 7‐year‐old, male, castrated, mixed‐breed dog presented with right pelvic limb lameness and pain on posturing to defecate that began 1.5 years prior to presentation. Radiographs taken 8 months prior to presentation showed a small lytic lesion of the L6 vertebral body, and CBCs showed a persistently increased hematocrit (HCT) for at least 2 ...
Samuel V. Neal   +11 more
wiley   +1 more source

POF1B Localizes to Desmosomes and Regulates Cell Adhesion in Human Intestinal and Keratinocyte Cell Lines

open access: yes, 2015
By means of morphological and biochemical criteria, we here provide evidence for the localization and function of premature ovarian failure, 1B (POF1B) in desmosomes.
A. Crespi   +15 more
core   +1 more source

Desmosomes in disease: a guide for clinicians [PDF]

open access: yes, 2017
The large number of diseases occurring when desmosome constituents are impaired provides striking evidence for the key role of desmosomes in maintaining tissue integrity.
Celentano, A, Cirillo, N
core   +1 more source

Hypoxia and the cytoskeleton

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Hyper-adhesion in desmosomes: Its regulation in wound healing and possible relationship to cadherin crystal structure

open access: yes, 2005
The resistance of tissues to physical stress is dependent upon strong cell-cell adhesion in which desmosomes play a crucial role. We propose that desmosomes fulfil this function by adopting a more strongly adhesive state, hyper-adhesion, than other ...
Tabernero, Lydia; id_orcid   +4 more
core   +1 more source

Autoantibodies in Patients With Arrhythmogenic Cardiomyopathy Activate GSK‐3β, Resulting in a Loss of Cardiomyocyte Cohesion

open access: yesActa Physiologica, Volume 242, Issue 7, July 2026.
ABSTRACT Background Arrhythmogenic cardiomyopathy (ACM) is an inherited cardiac desmosome disease, as more than 50% of affected patients carry pathogenic variants in desmosome protein‐coding genes. In this study, we focused on the role and mechanisms of pathogenic and non‐pathogenic autoantibodies against intercalated disc (ICD) proteins such as ...
Soumyata Pathak   +15 more
wiley   +1 more source

Desmosomes: New Perspectives on a Classic

open access: yes, 2007
Desmosomes are highly specialized anchoring junctions that link intermediate filaments to sites of intercellular adhesion, thus facilitating the formation of a supracellular scaffolding that distributes mechanical forces throughout a tissue.
Simpson, Cory L., Green, Kathleen J.
core   +1 more source

Elevated desmoglein‐2 expression in multiple myeloma is a prognostic marker across genomic subtypes with impact on high‐risk cytogenetics and a distinct gene expression profile

open access: yes
British Journal of Haematology, EarlyView.
Barbara J. McClure   +7 more
wiley   +1 more source

Tyrosine phosphorylation in desmosomes and hemidesmosomes of the corneal epithelium.

open access: yes, 1996
We examined the localization of phosphotyrosine (p-Tyr)-modified proteins in the normal corneal epithelium using affinity-purified rabbit anti-p-Tyr antibody.
M Takahashi   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy