Results 81 to 90 of about 4,329 (200)

Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans. [PDF]

PLoS ONE, 2014
The inflammatory component of non-alcoholic steatohepatitis (NASH) can lead to irreversible liver damage. Therefore there is an urgent need to identify novel interventions to combat hepatic inflammation.
Jogchum Plat, Tim Hendrikx, Veerle Bieghs, Mike L J Jeurissen, Sofie M A Walenbergh, Patrick J van Gorp, Els De Smet, Maurice Konings, Anita C E Vreugdenhil, Yasmin Dias Guichot, Sander S Rensen, Wim A Buurman, Jan Willem M Greve, Dieter Lütjohann, Ronald P Mensink, Ronit Shiri-Sverdlov   +15 more
doaj   +1 more source

Cholesterol-Metabolizing Enzyme Cytochrome P450 46A1 as a Pharmacologic Target for Alzheimer’s Disease [PDF]

, 2017
Cytochrome P450 46A1 (CYP46A1 or cholesterol 24-hydroxylase) controls cholesterol elimination from the brain and plays a role in higher order brain functions.
Arajawa, Hiroyuki, Constans, James, Landreth, Gary, Li, Young, Mast, Natalia, Maxfield, Erin, Pikuleva, Irina A., Saadane, Aicha, Valencia-Olvera, Ana   +8 more
core   +1 more source

Tracking Long‐Term Trends in Sockeye Salmon (Oncorhynchus nerka) Population Dynamics Using Sterol and Stanol Biomarkers in Lake Sediments

Journal of Geophysical Research: Biogeosciences, Volume 130, Issue 9, September 2025.
Abstract We analyzed biomarkers, including sterols, stanols, and δ15N, in sediment cores from lakes with well‐documented sockeye salmon return histories. Our goal was to improve estimates of past changes in salmon escapement, that is, the population that return to their freshwater nursery lakes, inferred using sediment biogeochemical markers ...
D. Dagodzo, D. C. Eickmeyer, L. E. Kimpe, D. T. Selbie, J. P. Smol, J. M. Blais   +5 more
wiley   +1 more source

Seasonal survey of the composition and degradation state of particulate organic matter in the Rhône River using lipid tracers [PDF]

, 2015
International audienceLipid tracers including fatty acids, hydroxyacids, n-alkanols, sterols and triterpenoids were used to determine the origin and fate of suspended particulate organic matter (POM) collected in the Rhône River (France).
Amiraux, Remi, Charrière, B., Galeron, M.-A, Garcia, N, Lagadec, V, Radakovitch, O., Raimbault, Patrick, Rontani, J.-F., Vaultier, F   +8 more
core   +5 more sources

Sterol imbalances and cholesterol‐24‐hydroxylase dysregulation is linked to the underlying progression of multiple sclerosis

Brain Pathology, Volume 35, Issue 5, September 2025.
We have sought to determine the role that cholesterol metabolism plays in disability worsening and its correlation with progressive MS by analysing patient CSF and post‐mortem tissues using cutting edge mass spectrometry approaches. Key sterol metabolites measured in the CSF link with important disability milestones at the very early stages of MS ...
Lauren Griffiths, Kristen Hawkins, Eylan Yutuc, Roberto Angelini, Racheal Fosuah, Manuela Pacciarini, Alison Dickson, Neil Robertson, Laura Childs, Samantha Loveless, Emma Tallantyre, William J. Griffiths, Yuqin Wang, Owain W. Howell   +13 more
wiley   +1 more source

The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity [PDF]

, 2015
ATP-binding cassette transporter G1 (ABCG1) promotes cholesterol efflux from cells and regulates intracellular cholesterol homeostasis. Here we demonstrate a role of ABCG1 as a mediator of tumour immunity.
Cekic, C., Hedrick, C.C., Linden J., Sag, D., Wu, R.   +4 more
core   +2 more sources

Analytical Study of Lanolin as Potential Biomarker of Prehistoric Sheep‐Shearing Practice

Chemistry–Methods, Volume 5, Issue 8, August 2025.
Lanolin, a complex wax found on sheep wool, accumulates on shearing tools, such as flint and obsidian blades, used since the Neolithic. This study explores lanolin's degradation patterns as a potential biomarker for prehistoric sheep‐shearing practices, employing micro‐Fourier transformed infrared spectroscopy, hyperspectral imaging, and gas ...
Claudia Adsuar Fuster, Francesco Caruso, Olivia Gómez‐Laserna, Martina Romani, Ramón J. Barrio, Josep Maria Vergès, Vincenza Forgia, Maite Maguregui, Asier Vallejo   +8 more
wiley   +1 more source

Neutral sterols of rat epididymis: high concentrations of dehydrocholesterols in rat caput epididymidis

Journal of Lipid Research, 2001
Phospholipids and sterols are known to have multiple functions in reproductive tissue of mammals. High concentrations of the cholesterol precursor desmosterol have been described in testis, epididymis, and spermatozoa of various species.
Bernhard Lindenthal, Tayseer A. Aldaghlas, Joanne K. Kelleher, Stephan M. Henkel, René Tolba, Gerhard Haidl, Klaus von Bergmann   +6 more
doaj   +1 more source

Low-fat nondairy minidrink containing plant stanol ester effectively reduces LDL cholesterol in subjects with mild to moderate hypercholesterolemia as part of a Western diet [PDF]

, 2013
Peer ...
Gylling, Helena, Hallikainen, Maarit, Olsson, Johan   +2 more
core   +2 more sources

Cholesterol and desmosterol in two sperm populations separated on Sil‐Select gradient [PDF]

International Journal of Andrology, 2010
SummarySperm lipids are important for sperm viability, maturity and function. This study aimed to identify cholesterol and desmosterol composition of human spermatozoa of two sperm populations separated on Sil‐Select gradient. Forty‐eight males were divided into four groups namely healthy men (n = 13), asthenozoospermia (n = 11 ...
A, Zalata, A, Hassan, A, Christophe, F, Comhaire, T, Mostafa   +4 more
openaire   +2 more sources