Results 131 to 140 of about 11,794,013 (339)

Direct measurement of the Wigner function by photon-number-resolving detection

, 2014
Photon-number-revolving (PNR) detection allows the direct measurement of the Wigner quasiprobability distribution of an optical mode without the need for numerically processing an inverse Radon transform [K. Banaszek and K. W\'odkiewicz, Phys. Rev. Lett.
Calkins, Brice, Gerrits, Thomas, Lita, Adriana, Miller, Aaron J., Nam, Sae Woo, Pfister, Olivier, Shahrokhshahi, Reihaneh, Sridhar, Niranjan   +7 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Characterization of some modern scintillators recommended for use on large fusion facilities in γ-ray spectroscopy and tomographic measurements of γ-emission profiles

Nukleonika, 2017
LaBr3:Ce,CeBr3 and GAGG:Ce scintillators were investigated and the determined characteristics were compared with those obtained for the well-known and widely used CsI:Tl and NaI:Tl crystals. All the detectors were of the same size of 10 × 10 × 5 mm3. The
Sibczynski Pawel, Broslawski Andrzej, Gojska Aneta, Kiptily Vasili, Korolczuk Stefan, Kwiatkowski Roch, Mianowski Slawomir, Moszyński Marek, Rzadkiewicz Jacek, Swiderski Lukasz, Szydlowski Adam, Zychor Izabella   +11 more
doaj   +1 more source

Efficient detection of quasiperiodicities in strings

Theoretical Computer Science, 1993
A strings \(z\) is quasiperiodic if there is a string \(w\neq z\) such that \(z\) is completely by (possibly overlapping) occurrences of \(w\) in \(z\). In this situation \(w\) is called a quasiperiod of \(z\). If \(z\) is quasiperiodic, then its shortest quasiperiod \(w\) is uniquely determined and is referred to as the quasiperiod of \(z\).
Apostolico, Alberto, Ehrenfeucht, Andrzej   +1 more
openaire   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Correlation of Calibration Parameters for HPGe Detector Efficiency Based on Monte Carlo Simulation

Yuanzineng kexue jishu
During the operation, maintenance, and eventual decommissioning of nuclear power plants, a significant amount of low and intermediate-level radioactive waste is generated.
LI Yan1, SHAN Chenyu2, GU Weiguo1, WANG Dezhong1
doaj   +1 more source

An algorithm for estimating the detection efficiency of a lightning location system

Geomatics, Natural Hazards & Risk, 2019
This article puts forward an algorithm for estimating the detection efficiency (DE) of a lightning location system (LLS). The algorithm can be applied to lightning flash/stroke density correction and LLS performance evaluation.
HaiBo Hu, Ying Wang, Xiya Zhang
doaj   +1 more source