Results 81 to 90 of about 1,688,460 (309)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Snake diversity, occupancy, and detection on Thailand's largest university campus

Ecology and Evolution
More than 240 species of snake have been described from Thailand, yet basic natural history and ecology for this group of animals remains scarce in human disturbed environments despite conservation and human medical significance of them in these habitats.
Curt H. Barnes, Ungku Zafirah Abdulaziz, Arwut Kaenphet, Chatchai Kanlayanapaphon   +3 more
doaj   +1 more source

A generalized method to determine detectability of rare and cryptic species using the ornate box turtle as a model

Wildlife Society Bulletin, 2011
Estimates regarding population parameters are often based on data from surveys. To ensure that such estimates are as accurate as possible, it is important to know the detectability resulting from the particular survey method used.
Jeanine M. Refsnider, Timothy S. Mitchell, Henry M. Streby, Jeramie T. Strickland, Daniel A. Warner, Fredric J. Janzen   +5 more
doaj   +1 more source

Table Detection via Probability Optimization [PDF]

, 2002
In this paper, we define the table detection problem as a probability optimization problem. We begin, as we do in our previous algorithm, finding and validating each detected table candidates. We proceed to compute a set of probability measurements for each of the table entities.
Yalin Wang, Ihsin T. Phillips, Robert M. Haralick   +2 more
openaire   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Electroshocking as a survey technique for stream‐dwelling amphibians

Wildlife Society Bulletin, 2012
Electroshocking has long been employed as a survey technique for fish, but has not been directly tested against rock rolling as a survey methodology for stream‐dwelling amphibians.
John O. Cossel Jr., Monica G. Gaige, Joel D. Sauder   +2 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Evaluation of an automated recording device for monitoring forest birds

Wildlife Society Bulletin, 2012
Monitoring of forest songbirds via auditory detections during point surveys can be enhanced by using preprogrammed recording devices. During May–July 2008, we compared boreal forest bird surveys conducted with SM‐1 bird song recorders (Wildlife Acoustics,
Lisa A. Venier, Stephen B. Holmes, George W. Holborn, Kenneth A. Mcilwrick, Glen Brown   +4 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Performance of binary FSK data transmission systems [PDF]

Matched-filter detection of binary signals is discussed in terms of the probability of bit error. The equations for the probability of error are derived for coherent phase shift keying, and coherent frequency shift keying (FSK).
Batson, B. H.
core   +1 more source