Cell Sorting Using Electrokinetic Deterministic Lateral Displacement [PDF]
We show that by combining deterministic lateral displacement (DLD) with electrokinetics, it is possible to sort cells based on differences in their membrane and/or internal structures.
Bao D. Ho +2 more
doaj +6 more sources
Deterministic Lateral Displacement: Challenges and Perspectives [PDF]
The advent of microfluidics in the 1990s promised a revolution in multiple industries from healthcare to chemical processing. Deterministic lateral displacement (DLD) is a continuous-flow microfluidic particle separation method discovered in 2004 that ...
Timm Krüger +30 more
core +5 more sources
Anisotropic permeability in deterministic lateral displacement arrays [PDF]
We investigate anisotropic permeability of microfluidic deterministic lateral displacement (DLD) arrays. A DLD array can achieve high-resolution bimodal size-based separation of micro-particles, including bioparticles such as cells.
Loutherback, Kevin +4 more
core +9 more sources
Multidirectional sorting modes in deterministic lateral displacement devices [PDF]
Deterministic lateral displacement (DLD) devices separate micrometer-scale particles in solution based on their size using a laminar microfluidic flow in an array of obstacles.
Heller, Martin +15 more
core +5 more sources
Deterministic lateral displacement for particle separation:a review [PDF]
Deterministic lateral displacement (DLD), a hydrodynamic, microfluidic technology, was first reported by Huang et al. in 2004 to separate particles on the basis of size in continuous flow with a resolution of down to 10 nm.
McGrath, J., Jimenez, M., Bridle, H.
core +7 more sources
Particle Separation with Deterministic Lateral Displacement (DLD): The Anisotropy Effect
Deterministic lateral displacement (DLD) is a passive and label-free microfluidic separation technique with a strong potential for biological sample preparation purposes. Numerical and experimental models have been proposed so far to predict the particle
Eloise Pariset +5 more
doaj +2 more sources
Active Posts in Deterministic Lateral Displacement Devices [PDF]
Using electrically connected metal-coated posts in a deterministic lateral displacement (DLD) device and applying electric fields, electrokinetics is used to tune separations, significantly decrease the critical size for separation, and increase the ...
Carlotta Guiducci +10 more
core +3 more sources
Degas-Driven Deterministic Lateral Displacement in Poly(dimethylsiloxane) Microfluidic Devices
In this work, degas-driven microfluidic deterministic lateral displacement devices were fabricated from poly(dimethylsiloxane). Two device configurations were considered: one with a single input for the enrichment of particles and the other one with ...
Takasi Nisisako (6297716) +1 more
core +3 more sources
Numerical Investigation on the Effects of Cell Deformability and DLD Microfluidic Device Geometric Parameters on the Isolation of Circulating Tumor Cells [PDF]
Deterministic Lateral Displacement (DLD) microfluidic devices provide a simple and passive separation method for the isolation of Circulating Tumor Cells (CTCs) in blood samples based on their biophysical properties.
Roya Mohammadali +2 more
doaj +1 more source
Inertia and scaling in deterministic lateral displacement [PDF]
The ability to separate and analyze chemical species with high resolution, sensitivity, and throughput is central to the development of microfluidics systems. Deterministic lateral displacement (DLD) is a continuous separation method based on the transport of species through an array of obstacles.
Bowman, Timothy J. +2 more
openaire +3 more sources

