Results 21 to 30 of about 1,415,248 (230)
Numerical study of microfluidic effects and red blood cell dynamics in 'deterministic lateral displacement' geometries [PDF]
The last two decades have seen microfluidics gaining increasing interest from the fields of medical diagnostics and bio-chemical processes, due to its immense potential for point-of-care diagnostic applications.
Vernekar, Rohan Ranganath
core +3 more sources
Label-free enrichment of functional cardiomyocytes using microfluidic deterministic lateral flow displacement. [PDF]
Progress in cardiac cell replacement therapies and tissue engineering critically depends on our ability to isolate functional cardiomyocytes (CMs) from heterogeneous cell mixtures.
Boyang Zhang +3 more
doaj +1 more source
Electrokinetic biased deterministic lateral displacement: scaling analysis and simulations [PDF]
Deterministic Lateral Displacement (DLD) is a microfluidic technique where arrays of micropillars within a microchannel deflect particles leading to size-based segregation. We recently demonstrated that applying AC electric fields orthogonal to the fluid flow increases the separation capabilities of these devices with a deflection angle that depends on
Victor Calero +3 more
openaire +5 more sources
Maximizing particle concentration in deterministic lateral displacement arrays [PDF]
We present an improvement to deterministic lateral displacement arrays, which allows higher particle concentration enhancement. We correct and extend previous equations to a mirror-symmetric boundary. This approach allows particles to be concentrated into a central channel, no wider than the surrounding gaps, thereby maximizing the particle enrichment.
Shilun Feng +4 more
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Charge-Based Separation of Micro- and Nanoparticles
Deterministic Lateral Displacement (DLD) is a label-free particle sorting method that separates by size continuously and with high resolution. By combining DLD with electric fields (eDLD), we show separation of a variety of nano and micro-sized particles
Bao D. Ho +2 more
doaj +1 more source
Deterministic lateral displacement (DLD) is a passive, label-free, continuous-flow method for particle separation. Since its discovery in 2004, it has been widely used in medical tests to separate blood cells, bacteria, extracellular vesicles, DNA, and ...
Alexander Zhbanov +2 more
doaj +1 more source
Circulating tumor cells (CTCs) are cancer cells that fall off from cancer lesions and enter the blood of human extracorporeal circulation. They are the early basis of judging cancer metastasis. However, CTCs are extremely rare, there is a great challenge
Yanjuan Wang +6 more
doaj +1 more source
Automated leukocyte processing by microfluidic deterministic lateral displacement [PDF]
AbstractWe previously developed a Deterministic Lateral Displacement (DLD) microfluidic method in silicon to separate cells of various sizes from blood (Davis et al., Proc Natl Acad Sci 2006;103:14779‐14784; Huang et al., Science 2004;304:987‐990).
Curt I, Civin +16 more
openaire +2 more sources
Deterministic lateral displacement (DLD) is a promising technology that allows for the continuous and the size-based separation of suspended particles at a high resolution through periodically arrayed micropillars.
Naotomo Tottori, Takasi Nisisako
doaj +1 more source
Centrifugal deterministic lateral displacement separation system [PDF]
This work investigates the migration of spherical particles of different sizes in a centrifuge-driven deterministic lateral displacement (c-DLD) device. Specifically, we use a scaled-up model to study the motion of suspended particles through a square array of cylindrical posts under the action of centrifugation.
Jiang, Mingliang +2 more
openaire +3 more sources

