Results 21 to 30 of about 1,415,248 (230)

Numerical study of microfluidic effects and red blood cell dynamics in 'deterministic lateral displacement' geometries [PDF]

open access: yes, 2019
The last two decades have seen microfluidics gaining increasing interest from the fields of medical diagnostics and bio-chemical processes, due to its immense potential for point-of-care diagnostic applications.
Vernekar, Rohan Ranganath
core   +3 more sources

Label-free enrichment of functional cardiomyocytes using microfluidic deterministic lateral flow displacement. [PDF]

open access: yesPLoS ONE, 2012
Progress in cardiac cell replacement therapies and tissue engineering critically depends on our ability to isolate functional cardiomyocytes (CMs) from heterogeneous cell mixtures.
Boyang Zhang   +3 more
doaj   +1 more source

Electrokinetic biased deterministic lateral displacement: scaling analysis and simulations [PDF]

open access: yesJournal of Chromatography A, 2020
Deterministic Lateral Displacement (DLD) is a microfluidic technique where arrays of micropillars within a microchannel deflect particles leading to size-based segregation. We recently demonstrated that applying AC electric fields orthogonal to the fluid flow increases the separation capabilities of these devices with a deflection angle that depends on
Victor Calero   +3 more
openaire   +5 more sources

Maximizing particle concentration in deterministic lateral displacement arrays [PDF]

open access: yesBiomicrofluidics, 2017
We present an improvement to deterministic lateral displacement arrays, which allows higher particle concentration enhancement. We correct and extend previous equations to a mirror-symmetric boundary. This approach allows particles to be concentrated into a central channel, no wider than the surrounding gaps, thereby maximizing the particle enrichment.
Shilun Feng   +4 more
openaire   +2 more sources

Charge-Based Separation of Micro- and Nanoparticles

open access: yesMicromachines, 2020
Deterministic Lateral Displacement (DLD) is a label-free particle sorting method that separates by size continuously and with high resolution. By combining DLD with electric fields (eDLD), we show separation of a variety of nano and micro-sized particles
Bao D. Ho   +2 more
doaj   +1 more source

Current status and further development of deterministic lateral displacement for micro-particle separation

open access: yesMicro and Nano Systems Letters, 2023
Deterministic lateral displacement (DLD) is a passive, label-free, continuous-flow method for particle separation. Since its discovery in 2004, it has been widely used in medical tests to separate blood cells, bacteria, extracellular vesicles, DNA, and ...
Alexander Zhbanov   +2 more
doaj   +1 more source

A Two-Stage Separation of Circulating Tumor Cells Based on Deterministic Lateral Displacement and Dielectrophoresis Techniques

open access: yesIEEE Access, 2021
Circulating tumor cells (CTCs) are cancer cells that fall off from cancer lesions and enter the blood of human extracorporeal circulation. They are the early basis of judging cancer metastasis. However, CTCs are extremely rare, there is a great challenge
Yanjuan Wang   +6 more
doaj   +1 more source

Automated leukocyte processing by microfluidic deterministic lateral displacement [PDF]

open access: yesCytometry Part A, 2016
AbstractWe previously developed a Deterministic Lateral Displacement (DLD) microfluidic method in silicon to separate cells of various sizes from blood (Davis et al., Proc Natl Acad Sci 2006;103:14779‐14784; Huang et al., Science 2004;304:987‐990).
Curt I, Civin   +16 more
openaire   +2 more sources

Tunable deterministic lateral displacement of particles flowing through thermo-responsive hydrogel micropillar arrays

open access: yesScientific Reports, 2023
Deterministic lateral displacement (DLD) is a promising technology that allows for the continuous and the size-based separation of suspended particles at a high resolution through periodically arrayed micropillars.
Naotomo Tottori, Takasi Nisisako
doaj   +1 more source

Centrifugal deterministic lateral displacement separation system [PDF]

open access: yesMicrofluidics and Nanofluidics, 2015
This work investigates the migration of spherical particles of different sizes in a centrifuge-driven deterministic lateral displacement (c-DLD) device. Specifically, we use a scaled-up model to study the motion of suspended particles through a square array of cylindrical posts under the action of centrifugation.
Jiang, Mingliang   +2 more
openaire   +3 more sources

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