Results 81 to 90 of about 25,370 (238)
KV7 channels in the human detrusor: channel modulator effects and gene and protein expression
, 2017 Voltage-gated type 7 K+ (KV7 or KCNQ) channels regulate the contractility of various smooth muscles. With this study, we aimed to assess the role of KV7 channels in the regulation of human detrusor contractility, as well as the gene and protein ...
Mancuso, Cesare +5 more
core +1 more source
Third‐Line Overactive Bladder Treatments: Cost–Benefit Analysis in an Australian Public Hospital
ANZ Journal of Surgery, EarlyView.ABSTRACT Introduction and Objectives To review the efficacy and cost‐effectiveness of third‐line overactive bladder (OAB) managements, including percutaneous tibial nerve stimulation (PTNS), intravesical botulinum toxin A (Botox) and sacral neuromodulation (SNM) in the urology department of a tertiary public hospital.
Rowan Klein Nulend +4 more
wiley +1 more source
Connexin45 expression in the human obstructed detrusor muscle
, 2009 PURPOSE: Patients with benign prostatic hyperplasia (BPH) and bladder outlet obstruction (BOO) frequently develop lower urinary tract symptoms (LUTS).
Walch, M +7 more
core +1 more source
Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial
BJU International, Volume 135, Issue 4, Page 638-647, April 2025.Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui +2 more
wiley +1 more source
Muscarinic receptor-induced contractions of the detrusor are impaired in TRPC4 deficient mice
, 2018 Acetylcholine contracts the bladder by binding to muscarinic M3 receptors on the detrusor, leading to Ca2+ influx via voltage-gated Ca2+ channels.
Gerard P. Sergeant +3 more
core +1 more source
Aquablation as salvage therapy for benign prostatic hyperplasia: an international multicentre study
BJU International, EarlyView.Objective Our objective was to evaluate the safety and effectiveness of Aquablation® as a salvage therapy in patients who underwent prior intervention for benign prostatic hyperplasia (BPH). Materials and Methods We retrospectively analysed 1887 consecutive men from the International Collaborative Aquablation Research Urology Society database between ...
Anouk Leathead +24 more
wiley +1 more source
Developmental Medicine &Child Neurology, EarlyView.Abstract Aim To systematically review the current evidence on physical therapy interventions for children and adolescents with myelomeningocele, the most complex and common presentation of spina bifida, to explore intervention components and the outcomes according to International Classification of Functioning, Disability and Health (ICF) domains, and ...
Lorena Costa Ferreira +3 more
wiley +1 more source
Tzu Chi Medical JournalObjectives: To investigate the functional role of chloride-dependent signaling pathways in urinary bladder smooth muscle (SM) contractility and to evaluate the expression of ClC-3 and CLCA4 in rat bladder tissue.
Yuh-Chen Kuo +5 more
doaj +1 more source
Limitations in using rabbit bladders in electrophysiological and urodynamic experiments
Veterinární Medicína, 2014 The aim of this study was to explore the possibility of using rabbit bladder as a model for experimental detrusor electrostimulation research. In a study of urinary bladder activity induced through electrostimulation of the ventral roots, the functional ...
P. Zerhau +6 more
doaj +1 more source