Results 71 to 80 of about 25,370 (238)

Depressed contractile responses to neurokinin A in idiopathic but not neurogenic overactive human detrusor muscle

, 2005
Objective The role of tachykinins such as neurokinin A in regulating bladder function is unclear, but NK2 receptors seem to mediate contraction in the human bladder and it has been suggested that these peptides may have a role in the pathophysiology of ...
Sellers, D. J., Hay, D. P. W., Chess-Williams, R., Chapple, C. R.   +3 more
core   +1 more source

Bladder Contractility Classification Before Bladder Outlet Surgery: Do BCI, Wmax and the Maastricht–Hannover Nomogram Agree and Does It Matter for Outcome?

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objectives The aim of this study was to assess the concordance between three classification systems (bladder contractility index, Maximum Watt's factor and Maastricht–Hannover nomogram) in allocating men to bladder contractility subgroups. Secondary aim was to explore whether preoperative contractility classification was associated with short ...
Selma Palthe, Nadine A. M. van Merode, Jeroen Kolenburg, Tom Marcelissen, Martijn G. Steffens, Gommert A. van Koeveringe, John P. Heesakkers, Lambertus P. W. Witte   +7 more
wiley   +1 more source

Perioperative Morbidity and Recurrence After One‐Stage Laparoscopic Resection for Multicompartment Deep Endometriosis: A Multicentre Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate perioperative morbidity, factors associated with postoperative complications and documented recurrence after one‐stage laparoscopic resection for multicompartment deep endometriosis. Design Retrospective multicentre cohort study. Setting Two tertiary referral centres specialised in endometriosis surgery (Bern, Switzerland;
Flavia Pagano, Pál Botond Sík, Sara Imboden, Attila Bokor, Michael D. Mueller   +4 more
wiley   +1 more source

Doxazosin Effects on Cholinergic and Adrenergic Responses in Rat Isolated Detrusor Smooth Muscle Preparations From Obstructed Bladder

Journal of Pharmacological Sciences, 2004
We investigated the effect of doxazosin on cholinergic and adrenergic agonists responses in detrusor smooth muscle preparations from sham-operated and 2-week partially obstructed rat bladders. Male Wistar albino rats, 200 – 250 g, were randomly allocated
Coşkun Usta, Erdal Kukul, Mehmet Yalçınkaya   +2 more
doaj   +1 more source

Role of ANO1‐Expressing PDGFRα+ Smooth Muscle Cells in Generating Spontaneous Phasic Contractions of the Rodent Epididymis

Andrology, EarlyView.
ABSTRACT Background Spontaneous phasic contractions (SPCs) in the epididymal duct play an important role in transport and maturation of sperm. In proximal cauda of the rat epididymis, platelet‐derived growth factor receptor α (PDGFRα)‐positive smooth muscle cells (SMCs) generate ANO1 Ca2+‐activated chloride channels (CaCCs)‐dependent spontaneous ...
Wataru Kudo, Hiromichi Takano, Toshiya Izuchi, Retsu Mitsui, Kyoko Miwa‐Nishimura, Hikaru Hashitani   +5 more
wiley   +1 more source

Studies of detrusor-sphincter synergia and dyssynergia during micturition in rats via fractional Brownian motion

, 2010
[[abstract]]© 2000 Institute of Electrical and Electronics Engineers-In normal humans, the bladder is supposed to empty by a synergistic contraction of the detrusor and relaxation of the sphincter during micturation.
Chang,Shyang;Mao,Shu-Ting;Hu,Shih-Jen;Lin,Wen-Ching;Cheng,Chen-Li
core   +1 more source

Urothelial MaxiK-activity regulates mucosal and detrusor metabolism. [PDF]

, 2017
There is increasing evidence for a role of MaxiK potassium channel-activity in regulating the metabolism and intracellular signaling of non-contractile bladder mucosal tissues.
Yi Wang, Gary G Deng, Kelvin P Davies
core   +1 more source

Androgen Receptor Expression in Urothelial Bladder Cancer—A Systematic Review and Meta‐Analysis

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Bladder cancer is a globally prevalent malignancy with a marked male predominance. Over the past decade, the androgen receptor has been investigated as a potential contributor to bladder cancer pathophysiology. Androgen receptor expression is most commonly assessed via immunohistochemistry, but its association with pathological ...
Alex Buckby, Mandana Gholami, Matthew Hong, Michael O'Callaghan   +3 more
wiley   +1 more source

Advances in the mechanisms of time-dependent changes in detrusor muscle in diabetic bladder dysfunction

Shiyong laonian yixue
Diabetic bladder dysfunction (DBD) is the most common chronic complication of diabetes mellitus in urology. Approximately 40%-60% of diabetic patients are troubled by DBD, presenting with varying degrees of lower urinary tract symptoms, mainly including ...
MENG Fanyu, DING Liucheng
doaj   +1 more source

Urodynamics in a community-dwelling population of females 80 years or older: which motive? Which diagnosis?

International Brazilian Journal of Urology, 2010
PURPOSE: To determine why community-dwelling women aged 80 years or over were referred for urodynamic evaluation despite their advanced age and which urodynamic diagnosis was made. MATERIALS AND METHODS: One hundred consecutive females (80-93 years) were
Françoise A. Valentini, Gilberte Robain, Brigitte G. Marti, Pierre P. Nelson   +3 more
doaj   +1 more source