Results 161 to 170 of about 19,734 (206)

Ubiquitin-centered post-translational modification crosstalk orchestrates tumor immunity and immunotherapy response. [PDF]

open access: yesExp Hematol Oncol
Qiao K   +9 more
europepmc   +1 more source

Deubiquitinating enzyme YOD1 deubiquitinates and destabilizes α-synuclein

Biochemical and Biophysical Research Communications, 2023
α-synuclein is one of the proteins involved in degenerative neuronal diseases such as Parkinson's disease (PD) or Lewy body dementia (LBD). The pathogenesis is imparted by the abnormal accumulation of α-synuclein resulting in the formation of a Lewy body (LB) and exerting neurotoxicity via an unknown mechanism.
Sang-Soo Park   +4 more
openaire   +2 more sources

The Deubiquitinating Enzymes

1998
As detailed elsewhere in this volume, modification of proteins by the 76-residue ubiquitin polypeptide is involved in many aspects of protein metabolism. Among the cellular processes affected by ubiquitin-dependent reactions are chromosome structure and segregation, cell-cycle progression, receptor-mediated signal transduction, gene expression, protein
Keith D. Wilkinson, Mark Hochstrasser
openaire   +1 more source

A new map to understand deubiquitination

Biochemical Society Transactions, 2010
Deubiquitination is a crucial mechanism in ubiquitin-mediated signalling networks. The importance of Dubs (deubiquitinating enzymes) as regulators of diverse cellular processes is becoming ever clearer as new roles are elucidated and new pathways are shown to be affected by this mechanism.
Katz, Elijah J.   +2 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy