Results 61 to 70 of about 38,233 (200)

Six Weeks of Low-Load Blood Flow Restricted and High-Load Resistance Exercise Training Produce Similar Increases in Cumulative Myofibrillar Protein Synthesis and Ribosomal Biogenesis in Healthy Males

Frontiers in Physiology, 2019
Purpose: High-load resistance exercise contributes to maintenance of muscle mass, muscle protein quality, and contractile function by stimulation of muscle protein synthesis (MPS), hypertrophy, and strength gains.
Peter Sieljacks, Jakob Wang, Thomas Groennebaek, Emil Rindom, Jesper Emil Jakobsgaard, Jon Herskind, Anders Gravholt, Andreas B. Møller, Robert V. Musci, Frank V. de Paoli, Karyn L. Hamilton, Benjamin F. Miller, Kristian Vissing   +12 more
doaj   +1 more source

Fractional Synthesis Rates of Individual Proteins in Rat Soleus and Plantaris Muscles

Proteomes, 2020
Differences in the protein composition of fast- and slow-twitch muscle may be maintained by different rates of protein turnover. We investigated protein turnover rates in slow-twitch soleus and fast-twitch plantaris of male Wistar rats (body weight 412 ±
Connor A. Stead, Stuart J. Hesketh, Samuel Bennett, Hazel Sutherland, Jonathan C. Jarvis, Paulo J. Lisboa, Jatin G. Burniston   +6 more
doaj   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Acidity Studies of Deuterated Acids and Bases Commonly Used as Buffers in NMR Studies [PDF]

, 1997
Structure based drug development is currently considered to be an important strategy for drug discovery. This strategy requires that critical knowledge of the three dimensional binding site on receptor molecules be known.
Godwin, Walter E., Green, M. Shane, McConnell, Rose M., Stanley, Brant   +3 more
core   +1 more source

Defect-related versus excitonic visible light emission from ion beam synthesized Si nanocrystals in SiO2 [PDF]

, 1996
Two sources of room temperature visible luminescence are identified from SiO2 films containing ion beam synthesized Si nanocrystals. From a comparison of luminescence spectra and photoluminescence decay lifetime measurements between Xe + -implanted SiO2 ...
Atwater, Harry A., Brongersma, M. L., Min, K. S., Polman, A., Shcheglov, K. V., Yang, C. M.   +5 more
core   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

The biological impact of deuterium and therapeutic potential of deuterium-depleted water

Frontiers in Pharmacology
Since its discovery by Harold Urey in 1932, deuterium has attracted increased amounts of attention from the scientific community, with many previous works aimed to uncover its biological effects on living organisms.
Jiao Qu, Jiao Qu, Yufei Xu, Shuang Zhao, Ling Xiong, Jing Jing, Su Lui, Juan Huang, Hubing Shi   +8 more
doaj   +1 more source

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

The effect of W surface fuzz induced by He plasma on deuterium permeation

Nuclear Fusion
The permeation and retention of hydrogen isotopes in nuclear materials is critical to issues such as hydrogen embrittlement, tritium self-sufficiency, and radioactive safety in fusion reactors. Tungsten, the primary candidate for plasma-facing materials,
Long Li, Ze Chen, Zhe Liu, Zeshi Gao, Na Zhang, Yangyang Li, Chao Yin, Shifeng Mao, Hirohiko Tanaka, Noriyasu Ohno, Minyou Ye   +10 more
doaj   +1 more source

Effect of D2O on increasing the neutron flux near a fueled capsule in the Plum Brook Mock-Up Reactor [PDF]

Deuterium oxide effect on increasing neutron flux near fueled capsule in nuclear reactor ...
Gumto, K. H.
core   +1 more source