Results 11 to 20 of about 75,331 (256)

Current Developments of Clinical Sequencing and the Clinical Utility of Polygenic Risk Scores in Inflammatory Diseases

Frontiers in Immunology, 2021
In this mini-review, we highlight selected research by the Deutsche Forschungsgemeinschaft (DFG) Cluster of Excellence “Precision Medicine in Chronic Inflammation” focusing on clinical sequencing and the clinical utility of polygenic risk scores as well ...
Matthias Hübenthal, Britt-Sabina Löscher, Jeanette Erdmann, Andre Franke, Damian Gola, Inke R. König, Hila Emmert   +6 more
doaj   +1 more source

Author Correction: Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system

Nature Communications, 2019
The original version of this Article omitted the following from the Acknowledgements: ‘This project was supported by CRC128/Project A03 of the Deutsche Forschungsgemeinschaft (DFG).’This has not been corrected in either the PDF or HTML versions.
H. Kaur, J. Carvalho, M. Looso, P. Singh, R. Chennupati, J. Preussner, S. Günther, J. Albarrán-Juárez, D. Tischner, S. Classen, S. Offermanns, N. Wettschureck   +11 more
doaj   +1 more source

Deutsche Forschungsberichte – eine Sonderform Grauer Literatur in der Technischen Informationsbibliothek (TIB)

o-bib. Das offene Bibliotheksjournal, 2022
Seit 1969 sammelt die Technische Informationsbibliothek (TIB) in Hannover auf gemeinsamen Vorschlag des Bundesministeriums für Bildung und Wissenschaft (BMBF) und der Deutschen Forschungsgemeinschaft (DFG) systematisch Deutsche Forschungsberichte ...
Elzbieta Gabrys-Deutscher, Andreas Lütjen   +1 more
doaj   +1 more source

The DFG Viewer for Interoperability in Germany

Liber Quarterly: The Journal of European Research Libraries, 2010
This article deals with the DFG Viewer for Interoperability, a free and open source web-based viewer for digitised books, and assesses its relevance for interoperability in Germany.
Ralf Goebel, Sebastian Meyer
doaj   +1 more source

Discuss Data: Community-zentrierter Ansatz für das Forschungsdatenmanagement in den Geistes- und Sozialwissenschaften

Bausteine Forschungsdatenmanagement, 2020
Dieser Artikel stellt einen Community-zentrierten Ansatz für das Forschungsdatenmanagement in den Geistes- und Sozialwissenschaften vor, der Daten explizit in einen Kontext zu ihrer Generierung, Nutzung und Кuratierung durch die entsprechenden ...
Felix Herrmann, Daniel Kurzawe
doaj   +1 more source

Vorstellung des Forschungsprojekts «INTERLOR - Lotharingien und das Papsttum. Interaktions-, Integrations- und Transformationsprozesse im Spannungsfeld zwischen zentraler Steuerung und regionaler Eigendynamik (11. - Anfang 13. Jahrhundert)»

Studi di Storia Medioevale e di Diplomatica: Nuova Serie, 2021
Der Text skizziert das mit dem Projekt «INTERLOR. Lotharingien und das Papsttum. Interaktions-, Integrations- und Transformationsprozesse im Spannungsfeld zwischen zentraler Steuerung und regionaler Eigendynamik (11. bis Anfang 13.
Harald Müller, Hannes Engl, Michel Margue, Timothy Salemme   +3 more
doaj   +1 more source

Insights into IGH clonal evolution in BCP-ALL: frequency, mechanisms, associations, and diagnostic implications

Frontiers in Immunology, 2023
IntroductionThe malignant transformation leading to a maturation arrest in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) occurs early in B-cell development, in a pro-B or pre-B cell, when somatic recombination of variable (V), diversity (D ...
Franziska Darzentas, Monika Szczepanowski, Michaela Kotrová, Alina Hartmann, Alina Hartmann, Alina Hartmann, Thomas Beder, Thomas Beder, Nicola Gökbuget, Stefan Schwartz, Stefan Schwartz, Lorenz Bastian, Lorenz Bastian, Lorenz Bastian, Claudia Dorothea Baldus, Claudia Dorothea Baldus, Claudia Dorothea Baldus, Karol Pál, Nikos Darzentas, Monika Brüggemann, Monika Brüggemann, Monika Brüggemann   +21 more
doaj   +1 more source

Personality matters – The interplay between consistent individual differences and mouse welfare in female C57BL6/J mice

Frontiers in Animal Science
To ensure good welfare of animals in human hands, it is essential to modify housing conditions according to the animals’ needs. Traditionally, the effects of such modifications are studied by means of group-level comparisons, thereby widely neglecting ...
Marlene G. U. Sroka, Marlene G. U. Sroka, Oliver Ambree, Oliver Ambree, Celina Dohmen, Celina Dohmen, Rupert Palme, Sylvia Kaiser, Sylvia Kaiser, S. Helene Richter, S. Helene Richter   +10 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source