Results 41 to 50 of about 14,908,548 (354)
Pharmaceutics, 2023 Dissolution limitations to oral absorption can occur if the time required for dissolution is longer than the transit time across the small intestine and/or if dissolution is slower than the drug’s permeation through the gut wall.
Kristian Beran +4 more
semanticscholar +1 more source
Two ways to Grid: the contribution of Open Grid Services Architecture (OGSA) mechanisms to service-centric and resource-centric lifecycles [PDF]
, 2006 Service Oriented Architectures (SOAs) support service lifecycle tasks, including Development, Deployment, Discovery and Use. We observe that there are two disparate ways to use Grid SOAs such as the Open Grid Services Architecture (OGSA) as exemplified ...
Brebner, P., Emmerich, W.
core +1 more source
Developed-developing country partnerships: Benefits to developed countries? [PDF]
Globalization and Health, 2012 Abstract Developing countries can generate effective solutions for today’s global health challenges. This paper reviews relevant literature to construct the case for international cooperation, and in particular, developed-developing country partnerships.
Syed, Shamsuzzoha B +10 more
openaire +4 more sources
Antibody Therapeutics, 2022 Developability refers to the likelihood that an antibody candidate will become a manufacturable, safe and efficacious drug. Although the safety and efficacy of a drug candidate will be well considered by sponsors and regulatory agencies, developability ...
Weijie Zhang +5 more
semanticscholar +1 more source
Nanoscale integration of single cell biologics discovery processes using optofluidic manipulation and monitoring. [PDF]
, 2019 The new and rapid advancement in the complexity of biologics drug discovery has been driven by a deeper understanding of biological systems combined with innovative new therapeutic modalities, paving the way to breakthrough therapies for previously ...
Chen, Ching +17 more
core +1 more source
, 2016 Is it possible, and in the first place is it even desirable, to define what "development" means and to determine the scope of the field called "developmental biology"? Though these questions appeared crucial for the founders of "developmental biology" in the 1950s, there seems to be no consensus today about the need to address them. Here, in a combined
Pradeu, Thomas +8 more
openaire +4 more sources
Molecules, 2023 In the quest to market increasingly safer and more potent biotherapeutic proteins, the concept of the multi-attribute method (MAM) has emerged from biopharmaceutical companies to boost the quality-by-design process development.
Claire I. Butré +8 more
doaj +1 more source
mAbs, 2021 Next-generation multi-specific antibody therapeutics (MSATs) are engineered to combine several functional activities into one molecule to provide higher efficacy compared to conventional, mono-specific antibody therapeutics.
Norbert Furtmann +16 more
doaj +1 more source
Communications Biology, 2023 Interleukin-2 (IL-2) engineered versions, with biased immunological functions, have emerged from yeast display and rational design. Here we reshaped the human IL-2 interface with the IL-2 receptor beta chain through the screening of phage-displayed ...
G. Rojas +19 more
semanticscholar +1 more source
The Statistics of Crumpled Paper [PDF]
, 2005 A statistical study of crumpled paper is allowed by a minimal 1D model: a self-avoiding line bent at sharp angles -- in which resides the elastic energy -- put in a confining potential.
A. Lobkovsky +8 more
core +3 more sources