Results 61 to 70 of about 16,267,247 (278)

Developing a framework for development: A discussion [PDF]

open access: yesDevelopmental Psychobiology, 2006
AbstractA multitude of scientific disciplines study the development of behavior. Their use of different methodological and conceptual approaches makes integration of findings difficult. In a symposium at the 38th Annual Meeting of the International Society for Developmental Psychobiology in Washington DC, the question was discussed if a general theory ...
Patrick, Bateson   +3 more
openaire   +2 more sources

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian   +13 more
wiley   +1 more source

A Stratified Analysis of Supersaturation and Precipitation Effects Based on the Refined Developability Classification System (rDCS).

open access: yesJournal of Pharmacy and Science
Supersaturation and precipitation within the gastrointestinal tract can influence oral absorption of active pharmaceutical ingredients (APIs). Supersaturation of weakly basic APIs upon transfer from the stomach into the small intestine may enhance their ...
Kristian Beran   +4 more
semanticscholar   +1 more source

Developable mechanisms on developable surfaces

open access: yesScience Robotics, 2019
Developable mechanisms are proposed as next-generation mechanical systems that can conform to and emerge from developable surfaces.
Todd G. Nelson   +4 more
openaire   +3 more sources

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

Developing Drugs For Developing Countries [PDF]

open access: yesHealth Affairs, 2006
Infectious and parasitic diseases create enormous health burdens, but because most of the people suffering from these diseases are poor, little is invested in developing treatments. We propose that developers of treatments for neglected diseases receive a "priority review voucher." The voucher could save an average of one year of U.S.
David B, Ridley   +2 more
openaire   +2 more sources

Phage Display Libraries for Antibody Therapeutic Discovery and Development

open access: yesAntibodies, 2019
Phage display technology has played a key role in the remarkable progress of discovering and optimizing antibodies for diverse applications, particularly antibody-based drugs.
Juan C. Almagro   +3 more
doaj   +1 more source

Antibody Conjugates-Recent Advances and Future Innovations

open access: yesAntibodies, 2020
Monoclonal antibodies have evolved from research tools to powerful therapeutics in the past 30 years. Clinical success rates of antibodies have exceeded expectations, resulting in heavy investment in biologics discovery and development in addition to ...
Donmienne Leung   +5 more
doaj   +1 more source

Interlaboratory Evaluation of a User-Friendly Benchtop Mass Spectrometer for Multiple-Attribute Monitoring Studies of a Monoclonal Antibody

open access: yesMolecules, 2023
In the quest to market increasingly safer and more potent biotherapeutic proteins, the concept of the multi-attribute method (MAM) has emerged from biopharmaceutical companies to boost the quality-by-design process development.
Claire I. Butré   +8 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi   +10 more
wiley   +1 more source

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