Results 51 to 60 of about 4,721 (285)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges +12 more
wiley +1 more source
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
Interactive procedural simulation of paper tearing with sound [PDF]
, 2015 International audienceWe present a phenomenological model for the real-time simulation of paper tearing and sound. The model uses as input rotations of the hand along with the index and thumb of left and right hands to drive the position and orientation
Blanc-Beyne, Thibault +7 more
core +4 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine +14 more
wiley +1 more source
Statistical Mechanics of Developable Ribbons
, 2010 We investigate the statistical mechanics of long developable ribbons of finite width and very small thickness. The constraint of isometric deformations in these ribbon-like structures that follows from the geometric separation of scales introduces a ...
Giomi, L., Mahadevan, L.
core +1 more source
Infinitesimal isometries on developable surfaces and asymptotic theories for thin developable shells [PDF]
, 2012 We perform a detailed analysis of first order Sobolev-regular infinitesimal isometries on developable surfaces without affine regions. We prove that given enough regularity of the surface, any first order infinitesimal isometry can be matched to an ...
Marta Lewicka +3 more
core +4 more sources
Phage Display Libraries for Antibody Therapeutic Discovery and Development
Antibodies, 2019 Phage display technology has played a key role in the remarkable progress of discovering and optimizing antibodies for diverse applications, particularly antibody-based drugs.
Juan C. Almagro +3 more
doaj +1 more source
Antibody Conjugates-Recent Advances and Future Innovations
Antibodies, 2020 Monoclonal antibodies have evolved from research tools to powerful therapeutics in the past 30 years. Clinical success rates of antibodies have exceeded expectations, resulting in heavy investment in biologics discovery and development in addition to ...
Donmienne Leung +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Rigidity and regularity of co-dimension one Sobolev isometric immersions [PDF]
, 2013 We prove the developability and $C^{1,1/2}$ regularity of $W^{2,2}$ isometric immersions of $n$-dimensional domains into $R^{n+1}$. As a conclusion we show that any such Sobolev isometry can be approximated by smooth isometries in the $W^{2,2}$ strong ...
Mohammad, Reza Pakzad, Zhuomin Liu
core