Results 51 to 60 of about 3,538 (271)
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager +8 more
wiley +1 more source
Phage Display Libraries for Antibody Therapeutic Discovery and Development
Phage display technology has played a key role in the remarkable progress of discovering and optimizing antibodies for diverse applications, particularly antibody-based drugs.
Juan C. Almagro +3 more
doaj +1 more source
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak +5 more
wiley +1 more source
Developing Drugs For Developing Countries [PDF]
Infectious and parasitic diseases create enormous health burdens, but because most of the people suffering from these diseases are poor, little is invested in developing treatments. We propose that developers of treatments for neglected diseases receive a "priority review voucher." The voucher could save an average of one year of U.S.
David B, Ridley +2 more
openaire +2 more sources
Antibody Conjugates-Recent Advances and Future Innovations
Monoclonal antibodies have evolved from research tools to powerful therapeutics in the past 30 years. Clinical success rates of antibodies have exceeded expectations, resulting in heavy investment in biologics discovery and development in addition to ...
Donmienne Leung +5 more
doaj +1 more source
In the quest to market increasingly safer and more potent biotherapeutic proteins, the concept of the multi-attribute method (MAM) has emerged from biopharmaceutical companies to boost the quality-by-design process development.
Claire I. Butré +8 more
doaj +1 more source
Developability and related properties of the generalized compact-open topology [PDF]
Developability and related properties (like weak developability,Gd-diagonal, G*d-diagonal, submetrizability) of the generalized compact-open topology tC on partial continuous functions P with closed domains in X and values in Y are studied.
Zsilinszky, Laszlo +1 more
core
On increasing the developability of a trimmed NURBS surface
Developable surfaces are desired in designing products manufactured from planar sheets. Trimmed non-uniform rational B-spline (NURBS) surface patches are widely adopted to represent 3D products in CAD/CAM. This paper presents a new method to increase the
Wang, Charlie C.L. +3 more
core +1 more source
Global Efforts to Reduce Paediatric Cancer Care Disparities in Radiotherapy: A Decade Change
ABSTRACT Background We present an update on the status, needs and challenges faced by paediatric imaging and radiotherapy (RT) programmes globally after a previous survey conducted by the International Atomic Energy Agency (IAEA) 10 years prior. Methods We developed and distributed a 121‐question survey to radiation oncologists, medical physicists and ...
Raymond B. Mailhot Vega +10 more
wiley +1 more source
Developing biobanks in developing countries.
We call for the development of human biobanks in developing countries and describe several examples from low income countries which are already building their own biobanks. Developing human biobanks in developing countries requires strengthening of the research capacity to use the new technologies, as well as a shift in research investment priorities ...
Igor Rudan +2 more
openaire +3 more sources

