Results 181 to 190 of about 580,764 (305)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

When imaging technology meets single-cell omics: new paradigm in developmental biology. [PDF]

Cell Regen
Wang C, Zhang X, Zhang Y, Liu F.
europepmc   +1 more source

Advances and Challenges in Spatial Transcriptomics for Developmental Biology. [PDF]

Biomolecules, 2023
Choe K, Pak U, Pang Y, Hao W, Yang X.
europepmc   +1 more source

Frontiers in Cell and Developmental Biology, Genetics, Nutrition and Physiology

Lipidology is a specialty section of Frontiers in Cell and Developmental Biology, Frontiers in Genetics, Frontiers in Physiology and Frontiers in Nutrition.
RODRIGUEZ ESTRADA, MARIA TERESA
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

New Insights and Implications of Cell-Cell Interactions in Developmental Biology. [PDF]

Int J Mol Sci
Wu G, Liang Y, Xi Q, Zuo Y.
europepmc   +1 more source

Darwin's agential materials: evolutionary implications of multiscale competency in developmental biology. [PDF]

Cell Mol Life Sci, 2023
Levin M.
europepmc   +1 more source

Developmental Biology

, 1994
xviii,894 hal,;ill ...
Gilbert,Scott F.
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Developmental Biology and Seasonal Damage of the Grape Borer <i>Xylotrechus pyrrhoderus</i> in Grapevines. [PDF]

Insects
Zhang G, Jia Y, Wu H, Zhang Y, Ghanim M, Ma Y, Sun R.   +6 more
europepmc   +1 more source