Results 11 to 20 of about 74,276 (234)

Urine Organic Acids as Metabolic Indicators for Global Developmental Delay/Intellectual Disability in Chinese Children

Frontiers in Molecular Biosciences, 2021
Objective: The purpose of this study was to search for differential metabolites in urine organic acids, and to characterize metabolic features that can be used to identify metabolites for exploration of global developmental delay (GDD)/intellectual ...
Baiyu Chen, Baiyu Chen, Yalan Zhan, Yalan Zhan, Miriam Kessi, Miriam Kessi, Shimeng Chen, Shimeng Chen, Juan Xiong, Juan Xiong, Xiaolu Deng, Xiaolu Deng, Lifen Yang, Lifen Yang, Jing Peng, Jing Peng, Fei Yin, Fei Yin, Fang He, Fang He   +19 more
doaj   +1 more source

DNA methylation profiling at single-base resolution reveals gestational folic acid supplementation influences the epigenome of mouse offspring cerebellum

Frontiers in Neuroscience, 2016
It is becoming increasingly more evident that lifestyle, environmental factors, and maternal nutrition during gestation can influence the epigenome of the developing fetus and thus modulate the physiological outcome. Variations in the intake of maternal
Subit eBarua, Subit eBarua, Salomon eKuizon, W. Ted eBrown, Mohammed A. Junaid   +4 more
doaj   +1 more source

Intranasal insulin prevents anesthesia-induced hyperphosphorylation of tau in 3xTg-AD mice

Frontiers in Aging Neuroscience, 2014
Background: It is well documented that elderly individuals are at increased risk of cognitive decline after anesthesia. General anesthesia is believed to be a risk factor for Alzheimer’s disease (AD).
Yanxing eChen, Xiaoqin eRun, Zhihou eLiang, Yang eZhao, CHUN-LING eDAI, Khalid eIqbal, Fei eLiu, CHENG-XIN eGONG   +7 more
doaj   +1 more source

Prediction of life satisfaction from resting‐state functional connectome

Brain and Behavior, 2021
Background Better life satisfaction (LS) is associated with better psychological and psychiatric outcomes. To the best of our knowledge, no studies have examined prediction models for LS. Methods Using resting‐state functional magnetic resonance imaging (
Takashi Itahashi, Neda Kosibaty, Ryu‐Ichiro Hashimoto, Yuta Y. Aoki   +3 more
doaj   +1 more source

Assessment of demographic and perinatal predictors of non-response and impact of non-response on measures of association in a population-based case control study: findings from the Georgia Study to Explore Early Development

Emerging Themes in Epidemiology, 2018
Background Participation in epidemiologic studies has declined, raising concerns about selection bias. While estimates derived from epidemiologic studies have been shown to be robust under a wide range of scenarios, additional empiric study is needed ...
Laura A. Schieve, Shericka Harris, Matthew J. Maenner, Aimee Alexander, Nicole F. Dowling   +4 more
doaj   +1 more source

Prenatal to early postnatal neurotrophic treatment prevents Alzheimer-like behavior and pathology in mice

Alzheimer’s Research & Therapy, 2020
Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of middle-aged to old individuals. The pathophysiological process of AD is believed to begin many years before the emergence of clinical symptoms.
Wei Wei, Yifan Wang, Yinghua Liu, Chun-Ling Dai, Yunn-Chyn Tung, Fei Liu, Khalid Iqbal   +6 more
doaj   +1 more source

Young blood plasma reduces Alzheimer’s disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice

Alzheimer’s Research & Therapy, 2020
Background Recent studies indicated that circulatory factors in blood plasma from young animals can reactivate neurogenesis, restore synaptic plasticity, and improve cognitive function in aged animals.
Ying Zhao, Ran Qian, Jin Zhang, Fei Liu, Khalid Iqbal, Chun-Ling Dai, Cheng-Xin Gong   +6 more
doaj   +1 more source

Factors associated with pharmacological treatment in children with attention-deficit/hyperactivity disorders: a retrospective study of a series of 77 cases in a single third-level reference Centre in Apulia region

Italian Journal of Pediatrics, 2023
Background The present study analysed data on children and adolescents with a diagnosis of attention-deficit/hyperactivity disorder (ADHD) who were referred to the ADHD reference centre of Scientific Institute IRCCS E.
Simone Amendola, Isabella Fanizza, Sara Scoditti, Marta De Rinaldis, Antonio Trabacca   +4 more
doaj   +1 more source

Rare Copy Number Variations and Predictors in Children With Intellectual Disability and Epilepsy

Frontiers in Neurology, 2018
Introduction: The concurrence of intellectual disability/global developmental delay and epilepsy (ID/GDD-EP) is very common in the pediatric population. The etiologies for both conditions are complex and largely unknown.
Miriam Kessi, Miriam Kessi, Juan Xiong, Juan Xiong, Liwen Wu, Liwen Wu, Lifen Yang, Lifen Yang, Fang He, Fang He, Chen Chen, Chen Chen, Nan Pang, Nan Pang, Haolin Duan, Haolin Duan, Wen Zhang, Wen Zhang, Ahmed Arafat, Ahmed Arafat, Fei Yin, Fei Yin, Jing Peng, Jing Peng   +23 more
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Autism Spectrum Disorder Diagnostic Criteria Changes and Impacts on the Diagnostic Scales-Utility of the 2nd and 3rd Versions of the Gilliam Autism Rating Scale (GARS)

Brain Sciences, 2022
There is joint agreement among professionals internationally on the importance of diagnosing autism spectrum disorders (ASD) in the early stages of the emergence of symptoms. Criteria changes for the diagnosis of ASD need updated versions of the scale to
Sayyed Ali Samadi, Cemal A. Biçak, Hana Noori, Barez Abdalla, Amir Abdullah, Lizan Ahmed   +5 more
doaj   +1 more source