Results 61 to 70 of about 389,547 (323)

An evolutionarily conserved role for CTNNB1/β-CATENIN in regulating the development of the corpus callosum

iScience
Summary: The corpus callosum (CC) is a major nerve bundle that connects the two hemispheres of the brain. Dysgenesis of the CC is associated with neurodevelopmental disorders such as the CTNNB1 syndrome.
Arpan Parichha, Debarpita Datta, Amrita Singh, Ishita Talwar, Shreya Yadav, Mahima Bose, Varun Suresh, Špela Miroševič, Nina Žakelj, David Gosar, Damjan Osredkar, Shubha Tole   +11 more
doaj   +1 more source

SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex

iScience, 2023
Summary: Alternative pre-mRNA splicing plays critical roles in brain development. SRSF10 is a splicing factor highly expressed in central nervous system and plays important roles in maintaining normal brain functions.
Junjie Li, Hanyang Jiang, Yawei Mu, Zixuan Wei, Ankangzhi Ma, Menghan Sun, Jingjing Zhao, Cuiqing Zhu, Xianhua Chen   +8 more
doaj   +1 more source

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

FEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran, Gloriana Campos, Natalya M. Wells, Khanhlinh Lambuu, Isabelle Draper, Christina A. Pacak, Peter B. Kang   +6 more
wiley   +1 more source

Audio-visual speech perception: a developmental ERP investigation [PDF]

, 2013
Being able to see a talking face confers a considerable advantage for speech perception in adulthood. However, behavioural data currently suggest that children fail to make full use of these available visual speech cues until age 8 or 9.
Dick, Frederic, Karmiloff-Smith, Annette, Knowland, Victoria C.P., Mercure, E., Thomas, Michael S.C.   +4 more
core   +2 more sources

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Developmental arcs of plasticity in whole movement repertoires of a clonal fish

iScience
Summary: Developmental plasticity at the behavioral repertoire level allows animals to incrementally adjust their behavioral phenotypes to match their environments through ontogeny.
Sean M. Ehlman, Ulrike Scherer, David Bierbach, Luka Stärk, Marvin Beese, Max Wolf   +5 more
doaj   +1 more source

Transformational Potential: The Changing Face of God and of Self in the Realm of Science and Spirit [PDF]

, 2012
In this paper, the author examines the function and process of defining God, the Divine, or Ultimate Reality as a developmental process that begins in early childhood and continues throughout life.
Jacques, Jeannine
core   +1 more source

Exploring face perception in disorders of development: evidence from Williams syndrome and autism [PDF]

, 2008
Individuals with Williams syndrome (WS) and autism are characterized by different social phenotypes but have been said to show similar atypicalities of face-processing style.
Baron-Cohen, Baron-Cohen, Bellugi, Bellugi, Bellugi, Boucher, Brothers, Bruce, Bruce, Calder, Castelli, Deborah M. Riby, Deruelle, Deruelle, Dunn, Frigerio, Frith, Gepner, Gwyneth Doherty-Sneddon, Haxby, Hefter, Johnson, Jones, Karmiloff-Smith, Karmiloff-Smith, Karmiloff-Smith, Klin, Kylliäinen, Lopéz, Meyer-Lindenberg, Morris, Mottron, Peeters, Plesa-Skwerer, Raven, Reiss, Rutter, Schopler, Searcy, Singh, Strømme, Tager-Flusberg, Tassabehji, Teunisse, Teunisse, Thomas, Tranel, Vicki Bruce, Wing, Zebrowitz   +49 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

The amplitude of fNIRS hemodynamic response in the visual cortex unmasks autistic traits in typically developing children

Translational Psychiatry, 2022
Autistic traits represent a continuum dimension across the population, with autism spectrum disorder (ASD) being the extreme end of the distribution. Accumulating evidence shows that neuroanatomical and neurofunctional profiles described in relatives of ...
Raffaele Mazziotti, Elena Scaffei, Eugenia Conti, Viviana Marchi, Riccardo Rizzi, Giovanni Cioni, Roberta Battini, Laura Baroncelli   +7 more
doaj   +1 more source