Results 61 to 70 of about 407,893 (295)

Transformational Potential: The Changing Face of God and of Self in the Realm of Science and Spirit [PDF]

, 2012
In this paper, the author examines the function and process of defining God, the Divine, or Ultimate Reality as a developmental process that begins in early childhood and continues throughout life.
Jacques, Jeannine
core   +1 more source

Exploring face perception in disorders of development: evidence from Williams syndrome and autism [PDF]

, 2008
Individuals with Williams syndrome (WS) and autism are characterized by different social phenotypes but have been said to show similar atypicalities of face-processing style.
Baron-Cohen, Baron-Cohen, Bellugi, Bellugi, Bellugi, Boucher, Brothers, Bruce, Bruce, Calder, Castelli, Deborah M. Riby, Deruelle, Deruelle, Dunn, Frigerio, Frith, Gepner, Gwyneth Doherty-Sneddon, Haxby, Hefter, Johnson, Jones, Karmiloff-Smith, Karmiloff-Smith, Karmiloff-Smith, Klin, Kylliäinen, Lopéz, Meyer-Lindenberg, Morris, Mottron, Peeters, Plesa-Skwerer, Raven, Reiss, Rutter, Schopler, Searcy, Singh, Strømme, Tager-Flusberg, Tassabehji, Teunisse, Teunisse, Thomas, Tranel, Vicki Bruce, Wing, Zebrowitz   +49 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex

iScience, 2023
Summary: Alternative pre-mRNA splicing plays critical roles in brain development. SRSF10 is a splicing factor highly expressed in central nervous system and plays important roles in maintaining normal brain functions.
Junjie Li, Hanyang Jiang, Yawei Mu, Zixuan Wei, Ankangzhi Ma, Menghan Sun, Jingjing Zhao, Cuiqing Zhu, Xianhua Chen   +8 more
doaj   +1 more source

Theories of the development of human communication [PDF]

, 2013
This article considers evidence for innate motives for sharing rituals and symbols from animal semiotics, developmental neurobiology, physiology of prospective motor control, affective neuroscience and infant communication. Mastery of speech and language
Delafield-Butt, Jonathan, Trevarthen, Colwyn   +1 more
core  

Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis [PDF]

, 2013
Although mutations in the huntingtin gene (HTT) due to poly-Q expansion cause neuropathology in humans (Huntington's disease; HD), the normal function(s) of the gene and its protein (HTT) remain obscure.
Brown, Euan R., Idris, Mohammed M, Thorndyke, Michael C   +2 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Nonseparability of Shared Intentionality [PDF]

, 2009
According to recent studies in developmental psychology and neuroscience, symbolic language is essentially intersubjective. Empathetically relating to others renders possible the acquisition of linguistic constructs.
Bruza, Prof Peter, Flender, Mr Christian, Kitto, Dr Kirsty   +2 more
core  

Developmental neuroscience [PDF]

Current Opinion in Neurobiology, 2011
Arber, Silvia, Davis, Graeme
openaire   +5 more sources