Results 41 to 50 of about 961,843 (195)

A Joint Learning Framework of Visual Sensory Representation, Eye Movements, and Depth Representation for Developmental Robotic Agents [PDF]

open access: yes, 2017
In this paper, we propose a novel visual learning framework for developmental robotics agents which mimics the developmental learning concept from human infants.
Chong, Nak Young   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Developmental robotics : from babies to robots /

open access: yes, 2015
Developmental robotics is a collaborative and interdisciplinary approach to robotics that is directly inspired by the developmental principles and mechanisms observed in children's cognitive development.
Cangelosi, Angelo, Schlesinger, Matthew
core   +5 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A Database for Learning Numbers by Visual Finger Recognition in Developmental Neuro-Robotics

open access: yesFrontiers in Neurorobotics, 2021
Numerical cognition is a fundamental component of human intelligence that has not been fully understood yet. Indeed, it is a subject of research in many disciplines, e.g., neuroscience, education, cognitive and developmental psychology, philosophy of ...
Sergio Davies   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Enaction as a Conceptual Framework for Developmental Cognitive Robotics

open access: yesPaladyn, 2010
This paper provides an accessible introduction to the cognitive systems paradigm of enaction and shows how it forms a practical framework for robotic systems that can develop cognitive abilities.
Vernon David
doaj   +1 more source

Evolutionary Developmental Soft Robotics As a Framework to Study Intelligence and Adaptive Behavior in Animals and Plants

open access: yesFrontiers in Robotics and AI, 2017
In this paper, a comprehensive methodology and simulation framework will be reviewed, designed in order to study the emergence of adaptive and intelligent behavior in generic soft-bodied creatures.
Francesco Corucci   +6 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

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