Results 31 to 40 of about 275,688 (307)

On the developmental toxicity of silver nanoparticles

Materials & Design, 2021
With the increasing production and applications, silver nanoparticles (AgNPs) can be released into the air, water and soil environment, leading to direct exposure to human beings.
Jie Zhang, Sijin Liu, Jinxiang Han, Zhe Wang, Shuping Zhang   +4 more
doaj   +1 more source

Organ and prenatal toxicity of nonsteroidal anti-inflammatory drugs

Current Issues in Pharmacy and Medical Sciences, 2015
Non-selective cyclooxygenase (COX) inhibitors, commonly referred to as nonsteroidal anti-inflammatory drugs (NSAIDs), are among the most taken pharmaceuticals.
Dyndor Katarzyna, Dworzanski Wojciech, Pliszczynska-Steuden Małgorzata, Cendrowska-Pinkosz Monika, Chroscicki Tomasz, Dyndor Przemyslaw, Dworzanska Anna, Piasek Ewa, Piech Piotr, Ruchala Marcin, Golec Katarzyna, Hermanowicz-Dryka Teresa   +11 more
doaj   +1 more source

Neurobehavioural effects of developmental toxicity [PDF]

The Lancet Neurology, 2014
Neurodevelopmental disabilities, including autism, attention-deficit hyperactivity disorder, dyslexia, and other cognitive impairments, affect millions of children worldwide, and some diagnoses seem to be increasing in frequency. Industrial chemicals that injure the developing brain are among the known causes for this rise in prevalence.
Grandjean, Philippe, Landrigan, Philip
openaire   +4 more sources

Multi-Behavioral Endpoint Testing Of An 87-Chemical Compound Library In Freshwater Planarians [PDF]

, 2018
There is an increased recognition in the field of toxicology of the value of medium-to-high-throughput screening methods using in vitro and alternative animal models.
Collins, Eva-Maria S., Graham, A., Hagstrom, D., Hayes, P., Zhang, S.   +4 more
core   +3 more sources

Emerging exposures of developmental toxicants [PDF]

Current Opinion in Pediatrics, 2017
Purpose of review The purpose of this review is to identify emerging developmental toxicants that are understudied in children's health. Exposures may arise from new products designed to improve utility, to reduce toxicity, or to replace undesirable chemicals.
Mary S, Wolff, Jessie P, Buckley, Stephanie M, Engel, Rob S, McConnell, Dana B, Barr   +4 more
openaire   +2 more sources

Multi-walled carbon nanotubes-induced alterations in microRNA let-7 and its targets activate a protection mechanism by conferring a developmental timing control

Particle and Fibre Toxicology, 2017
Background Multi-walled carbon nanotubes (MWCNTs) have been produced and applied for diverse purposes. MWCNTs can potentially cause the adverse effects on organisms.
Li Zhao, Hanxiao Wan, Qizhan Liu, Dayong Wang   +3 more
doaj   +1 more source

Developmental defects induced by thiabendazole are mediated via apoptosis, oxidative stress and alteration in PI3K/Akt and MAPK pathways in zebrafish

Environment International, 2023
Thiabendazole, a benzimidazole fungicide, is widely used to prevent yield loss in agricultural land by inhibiting plant diseases derived from fungi. As thiabendazole has a stable benzimidazole ring structure, it remains in the environment for an extended
Junho Park, Garam An, Hahyun Park, Taeyeon Hong, Whasun Lim, Gwonhwa Song   +5 more
doaj   +1 more source

Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder

Frontiers in Pharmacology, 2018
Psoralen toxicity is an issue of wide concern. However, an assay for psoralen-induced developmental toxicity has not been reported to date. Moreover, the underlying mechanism of psoralen-induced developmental toxicity is unclear.
Qing Xia, Lingying Wei, Yun Zhang, Haotian Kong, Yongping Shi, Yongping Shi, Xue Wang, Xiqiang Chen, Liwen Han, Kechun Liu   +9 more
doaj   +1 more source

Generation of patient-derived induced pluripotent stem cell line UJSi004-A from ultra-treatment-resistant schizophrenia

Stem Cell Research
Schizophrenia is a severe mental illness with disabling effects. Induced pluripotent stem cells (iPSCs) are generated by reprogramming peripheral blood mononuclear cells (PBMCs) from patients with ultra-treatment-resistant schizophrenia (UTRS).
Siyu Xi, Bing Xue, Yupeng Wang, Zhenghua Shan, Tianchi Song, Jing Sun, Shengying Qin   +6 more
doaj   +1 more source

Acute toxicity of arsenic and oxidative stress responses in the embryonic development of the common South American toad Rhinella arenarum [PDF]

, 2015
Arsenic (As), a natural element of ecological relevance, is found in natural water sources throughout Argentina in concentrations between 0.01mg/L and 15mg/L. The autochthonous toad Rhinella arenarum was selected to study the acute toxicity of As and the
Adams, Bagnyukova, Beers, Bongiovanni, Brix, Brodeur, Bundschuh, Chen, Del Conte, Ellman, Evelson, Farnfield, Ferrari, Ferrari, Ferrari, Guidi, Habig, Kensler, Kobayashi, Kono, Lascano, Lascano, Lowry, Lu, Miller, Montagna, Moriarty, Rahman, Rankin, Rizzo, Soria, Sotomayor, Suhendrayatna, Ventura-Lima, Ventura-Lima, Venturino, Venturino, White   +37 more
core   +1 more source