Results 21 to 30 of about 2,744,821 (349)

On the developmental toxicity of silver nanoparticles

Materials & Design, 2021
With the increasing production and applications, silver nanoparticles (AgNPs) can be released into the air, water and soil environment, leading to direct exposure to human beings.
Jie Zhang, Sijin Liu, Jinxiang Han, Zhe Wang, Shuping Zhang   +4 more
doaj   +2 more sources

Enantioselective Toxicity of Tetramethrin to Different Developmental Stages of Zebrafish (Danio rerio)

Toxics
Chiral pesticides exhibit enantioselective differences in processes such as biological absorption, metabolism, and toxic effects. Organisms have different physiological characteristics at different developmental stages. Therefore, conducting enantiomeric
Jiqin Feng, Xintong Xu, Wenfei Huang, Honghong Gong, Xiaohui Sun, Jinsong Liu, Chao Xu, Weiping Liu   +7 more
doaj   +2 more sources

Combination of the BeWo b30 placental transport model and the embryonic stem cell test to assess the potential developmental toxicity of silver nanoparticles

Particle and Fibre Toxicology, 2020
Background Silver nanoparticles (AgNPs) are used extensively in various consumer products because of their antimicrobial potential. This requires insight in their potential hazards and risks including adverse effects during pregnancy on the developing ...
Ashraf Abdelkhaliq, Meike van der Zande, Ruud J. B. Peters, Hans Bouwmeester   +3 more
doaj   +2 more sources

Exploration of developmental toxicity mechanism of emerging environmental contaminants [PDF]

环境与职业医学
The health risk posed by emerging environmental contaminants has become a public concern. Increasing evidence indicate that maternal exposure to multiple emerging environmental contaminants disrupts embryonic development.
Tao CHEN, Yunhui ZHANG
doaj   +2 more sources

An oral developmental toxicity study of generic pesticide pinoxaden in rabbits [PDF]

Toxicology Reports
The safety assessment of pinoxaden by the Joint Meeting on Pesticide Residues (JMPR) established a NOAEL of 30 mg/kg bw/day for maternal and embryo/fetal toxicity from a rabbit developmental toxicity study.
Inna Rashkivska, Yana Kolianchuk, Mykola Prodanchuk, Nadiia Nedopytanska, Natalia Bubalo, Mojmir Mach   +5 more
doaj   +2 more sources

Zebrafish Embryo Developmental Toxicity Assay (ZEDTA) for Regulatory Testing-Protocol Optimization and Historical Control Data. [PDF]

Toxics
The Zebrafish Embryo Developmental Toxicity Assay (ZEDTA) is a promising and innovative method with potential to replace the screening of teratogenic substances in mammals during preclinical development.
van den Oetelaar D, Tobor-Kapłon MA, Reijnaers M, Beekhuijzen M.   +3 more
europepmc   +2 more sources

Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish

Journal of Hazardous Materials, 2022
Per- and polyfluoroalkyl substances (PFAS) are a class of widely used chemicals with limited human health effects data relative to the diversity of structures manufactured.
L. Truong, Yvonne Rericha, Preethi Thunga, Skylar W. Marvel, Dylan J Wallis, M. Simonich, J. Field, Dunping Cao, David M. Reif, R. Tanguay   +9 more
semanticscholar   +1 more source

Polystyrene Nanoplastic Exposure Induces Developmental Toxicity by Activating the Oxidative Stress Response and Base Excision Repair Pathway in Zebrafish (Danio rerio)

ACS Omega, 2022
The widespread accumulation of nanoplastics is a growing concern for the environmental and human health. However, studies on the mechanisms of nanoplastic-induced developmental toxicity are still limited.
Mei-ling Feng, Juanjuan Luo, Y. Wan, Jiannan Zhang (张剑南), Chunjiao Lu, Maya Wang, Lu Dai, Xiaoqian Cao, Xiaojun Yang, Yajun Wang   +9 more
semanticscholar   +1 more source

Human developmental toxicity mechanism of polybrominated biphenyl exposure and health risk regulation strategy for special populations

Ecotoxicology and Environmental Safety, 2022
Polybrominated biphenyls (PBBs) can bioaccumulate in nature and are toxic to humans. Long-time exposure to PBBs in pregnant women can lead to the birth of an infant with abnormal conditions.
Luze Yang, Peixuan Sun, Wenjin Zhao, Miao Liu   +3 more
doaj   +1 more source

Effects of Decamethylcyclopentasiloxane on Reproductive Systems in Female Rats

Toxics, 2023
The female reproductive system becomes fertile through the action of hormones involved in the hypothalamic-pituitary-ovarian axis. On the other hand, estrogen-like endocrine disruptors released into the environment come into contact with humans by ...
Jimin Lee, Kangmin Kim, Seon-Mi Park, Jin-Sook Kwon, Eui-Bae Jeung   +4 more
doaj   +1 more source