Results 21 to 30 of about 130,891 (267)

On the developmental toxicity of silver nanoparticles

Materials & Design, 2021
With the increasing production and applications, silver nanoparticles (AgNPs) can be released into the air, water and soil environment, leading to direct exposure to human beings.
Jie Zhang, Sijin Liu, Jinxiang Han, Zhe Wang, Shuping Zhang   +4 more
doaj   +1 more source

Organ and prenatal toxicity of nonsteroidal anti-inflammatory drugs

Current Issues in Pharmacy and Medical Sciences, 2015
Non-selective cyclooxygenase (COX) inhibitors, commonly referred to as nonsteroidal anti-inflammatory drugs (NSAIDs), are among the most taken pharmaceuticals.
Dyndor Katarzyna, Dworzanski Wojciech, Pliszczynska-Steuden Małgorzata, Cendrowska-Pinkosz Monika, Chroscicki Tomasz, Dyndor Przemyslaw, Dworzanska Anna, Piasek Ewa, Piech Piotr, Ruchala Marcin, Golec Katarzyna, Hermanowicz-Dryka Teresa   +11 more
doaj   +1 more source

Developmental and organ-specific toxicity of cucurbit[7]uril: in vivo study on zebrafish models† [PDF]

RSC Advances, 2015
The macrocyclic molecular container cucurbit[7]uril (CB[7]), the most water-soluble homologue in the cucurbit[n]uril family (n = 5–8, 10, 14), has been evaluated for its in vivo toxicity profile, including its developmental toxicity such as its effect on
Huanxian Chen, Judy Y. W. Chan, Xue Yang, Ian W. Wyman, David Bardelang, Donal H. Macartney, Simon M. Y. Lee, Ruibing Wang   +7 more
doaj   +1 more source

Multi-walled carbon nanotubes-induced alterations in microRNA let-7 and its targets activate a protection mechanism by conferring a developmental timing control

Particle and Fibre Toxicology, 2017
Background Multi-walled carbon nanotubes (MWCNTs) have been produced and applied for diverse purposes. MWCNTs can potentially cause the adverse effects on organisms.
Li Zhao, Hanxiao Wan, Qizhan Liu, Dayong Wang   +3 more
doaj   +1 more source

Neurobehavioural effects of developmental toxicity [PDF]

The Lancet Neurology, 2014
Neurodevelopmental disabilities, including autism, attention-deficit hyperactivity disorder, dyslexia, and other cognitive impairments, affect millions of children worldwide, and some diagnoses seem to be increasing in frequency. Industrial chemicals that injure the developing brain are among the known causes for this rise in prevalence.
Grandjean, Philippe, Landrigan, Philip
openaire   +5 more sources

Developmental defects induced by thiabendazole are mediated via apoptosis, oxidative stress and alteration in PI3K/Akt and MAPK pathways in zebrafish

Environment International, 2023
Thiabendazole, a benzimidazole fungicide, is widely used to prevent yield loss in agricultural land by inhibiting plant diseases derived from fungi. As thiabendazole has a stable benzimidazole ring structure, it remains in the environment for an extended
Junho Park, Garam An, Hahyun Park, Taeyeon Hong, Whasun Lim, Gwonhwa Song   +5 more
doaj   +1 more source

Generation of patient-derived induced pluripotent stem cell line UJSi004-A from ultra-treatment-resistant schizophrenia

Stem Cell Research
Schizophrenia is a severe mental illness with disabling effects. Induced pluripotent stem cells (iPSCs) are generated by reprogramming peripheral blood mononuclear cells (PBMCs) from patients with ultra-treatment-resistant schizophrenia (UTRS).
Siyu Xi, Bing Xue, Yupeng Wang, Zhenghua Shan, Tianchi Song, Jing Sun, Shengying Qin   +6 more
doaj   +1 more source

Psoralen Induces Developmental Toxicity in Zebrafish Embryos/Larvae Through Oxidative Stress, Apoptosis, and Energy Metabolism Disorder

Frontiers in Pharmacology, 2018
Psoralen toxicity is an issue of wide concern. However, an assay for psoralen-induced developmental toxicity has not been reported to date. Moreover, the underlying mechanism of psoralen-induced developmental toxicity is unclear.
Qing Xia, Lingying Wei, Yun Zhang, Haotian Kong, Yongping Shi, Yongping Shi, Xue Wang, Xiqiang Chen, Liwen Han, Kechun Liu   +9 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Generation of induced pluripotent stem cell line UJSi005-A from developmentally delayed schizophrenic patients

Stem Cell Research
Schizophrenia, a chronic mental health condition, is characterized by abnormalities in perception, emotions and behavior. We successfully generated induced pluripotent stem cells (iPSCs) from the peripheral blood mononuclear cells (PBMCs) of a patient ...
Xuan Xu, Bing Xue, Dingqi Zhang, Yupeng Wang, Bonan Chen, Zhenghua Shan, Wenzhuo Zhao, Tianxiao Qiu, Jing Sun, Shengying Qin   +9 more
doaj   +1 more source