Results 11 to 20 of about 515,791 (281)

Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone for Multiple Myeloma.

New England Journal of Medicine, 2023
BACKGROUND Daratumumab, a monoclonal antibody targeting CD38, has been approved for use with standard myeloma regimens. An evaluation of subcutaneous daratumumab combined with bortezomib, lenalidomide, and dexamethasone (VRd) for the treatment of ...
P. Sonneveld, M. Dimopoulos, M. Boccadoro, Hang Quach, P. J. Ho, M. Beksaç, C. Hulin, Elisabetta Antonioli, X. Leleu, S. Mangiacavalli, A. Perrot, M. Cavo, A. Belotti, A. Broijl, F. Gay, R. Mina, I. Nijhof, Niels W C J van de Donk, E. Katodritou, Fredrik H. Schjesvold, Anna Sureda Balari, L. Rosiñol, Michel Delforge, W. Roeloffzen, T. Silzle, A. Vangsted, H. Einsele, Andrew Spencer, R. Hájek, Artur Jurczyszyn, Sarah Lonergan, T. Ahmadi, Yanfang Liu, Jianping Wang, Diego Vieyra, E. M. van Brummelen, V. Vanquickelberghe, Anna Sitthi-Amorn, C. D. de Boer, R. Carson, P. Rodríguez-Otero, J. Bladé, P. Moreau   +42 more
semanticscholar   +1 more source

Effect of Dexamethasone in Hospitalized Patients with COVID-19: Preliminary Report

medRxiv, 2020
Background: Coronavirus disease 2019 (COVID-19) is associated with diffuse lung damage. Corticosteroids may modulate immune-mediated lung injury and reducing progression to respiratory failure and death.
P. Horby, W. Lim, J. Emberson, M. Mafham, Jennifer L. Bell, L. Linsell, N. Staplin, C. Brightling, A. Ustianowski, E. Elmahi, B. Prudon, C. Green, T. Felton, D. Chadwick, K. Rege, C. Fegan, L. Chappell, S. Faust, T. Jaki, K. Jeffery, A. Montgomery, K. Rowan, E. Juszczak, J. Baillie, R. Haynes, M. Landray   +25 more
semanticscholar   +1 more source

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

New England Journal of Medicine, 2020
Background Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce progression to respiratory failure and death.
P. Horby, W. Lim, J. Emberson, M. Mafham, Jennifer L Bell, Louise Linsell, N. Staplin, C. Brightling, A. Ustianowski, E. Elmahi, B. Prudon, C. Green, T. Felton, D. Chadwick, K. Rege, C. Fegan, L. Chappell, S. Faust, T. Jaki, K. Jeffery, A. Montgomery, K. Rowan, Edmund Juszczak, J. Baillie, R. Haynes, M. Landray   +25 more
semanticscholar   +1 more source

Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: The CoDEX Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance Acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) is associated with substantial mortality and use of health care resources. Dexamethasone use might attenuate lung injury in these patients.
B. Tomazini, I. Maia, A. Cavalcanti, O. Berwanger, R. Rosa, V. Veiga, Á. Avezum, R. Lopes, F. Bueno, M. V. A. O. Silva, F. P. Baldassare, E. Costa, R. A. B. Moura, M. O. Honorato, A. N. Costa, L. Damiani, T. Lisboa, Letícia Kawano-Dourado, F. Zampieri, G. Olivato, C. Righy, C. P. Amêndola, R. Roepke, D. H. M. Freitas, D. N. Forte, F. G. Freitas, C. Fernandes, L. Melro, Gedealvares F S Junior, Douglas Costa Morais, S. Zung, F. Machado, L. Azevedo   +32 more
semanticscholar   +1 more source

The Effect of Dexamethasone Treatment on COVID-19 Prognosis in Cancer Patients

Vaccines, 2022
Background: Dexamethasone is used to treat cancer, relieve chemotherapy-induced nausea and vomiting, enhance cancer patients’ appetites, and treat COVID-19 patients. There is little evidence of the impact of a dexamethasone treatment plan on the severity
Lina Souan, Zienab Al-Khairy, Maysaa’ Adnan Al-Binni, Abdelkader Battah, Maher A. Sughayer   +4 more
doaj   +1 more source

Adjuvant Migraine Medications in the Treatment of Sudden Sensorineural Hearing Loss. [PDF]

, 2021
Objectives/hypothesisTo examine the hearing outcomes of patients with sudden sensorineural hearing loss (SSNHL) treated with oral and intratympanic (IT) steroid only or a combination of steroid and migraine treatment.
Abouzari, Mehdi, Chua, Janice T, Djalilian, Hamid R, Goshtasbi, Khodayar, Lin, Harrison W, Saber, Tina, Sarna, Brooke, Tan, Donald   +7 more
core   +1 more source

Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial.

Journal of the American Medical Association (JAMA), 2021
Importance A daily dose with 6 mg of dexamethasone is recommended for up to 10 days in patients with severe and critical COVID-19, but a higher dose may benefit those with more severe disease.
M. W. Munch, S. Myatra, B. Vijayaraghavan, S. Saseedharan, T. Benfield, R. R. Wahlin, B. Rasmussen, A. S. Andreasen, Lone M. Poulsen, L. Cioccari, M. Khan, F. Kapadia, J. Divatia, A. C. Brøchner, M. Bestle, M. Helleberg, J. Michelsen, Ajay Padmanaban, N. Bose, A. Møller, K. Borawake, K. T. Kristiansen, U. Shukla, M. Chew, S. Dixit, C. Ulrik, P. Amin, R. Chawla, C. Wamberg, Mehul Shah, I. S. Darfelt, V. Jørgensen, M. Smitt, A. Granholm, M. N. Kjær, M. Møller, T. Meyhoff, G. K. Vesterlund, N. Hammond, S. Micallef, Abhinav Bassi, Oommen John, Anubhuti Jha, M. Cronhjort, S. Jakob, C. Gluud, T. Lange, Vaijayanti Kadam, Klaus V. Marcussen, J. Hollenberg, A. Hedman, H. Nielsen, O. Schjørring, M. Q. Jensen, J. W. Leistner, T. Jonassen, C. M. Kristensen, Esben C. Clapp, C. J. Hjortsø, T. S. Jensen, Liv S. Halstad, Emilie R. B. Bak, Reem Zaabalawi, Matias Metcalf-Clausen, Suhayb Abdi, E. Hatley, Tobias S. Aksnes, Emil Gleipner-Andersen, Arif F. Alarcón, Gabriel Yamin, Adam Heymowski, Andreas Berggren, Kirstine N la Cour, Sarah Weihe, A. H. Pind, Janus Engstrøm, V. Jha, B. Venkatesh, A. Perner   +78 more
semanticscholar   +1 more source

Factors associated with the response to postnatal dexamethasone use in very low birthweight infants: a nationwide cohort study

BMJ Paediatrics Open, 2023
Background Dexamethasone is widely used as a systemic corticosteroid to treat and prevent bronchopulmonary dysplasia (BPD) in preterm infants. We evaluated the current epidemiology of dexamethasone use to prevent BPD and analyse the factors associated ...
Soon Min Lee, Min Soo Park, So Jin Yoon, In Gyu Song, Seung Hwan Baek, Jeong Eun Shin, Jungho Han, Joonsik Park, Su Min Lee, Sungbo Shim, Ho Seon Eun, Joohee Lim, Wook Chang   +12 more
doaj   +1 more source

Baricitinib plus dexamethasone compared to dexamethasone for the treatment of severe COVID-19 pneumonia: A retrospective analysis

Journal of Microbiology, Immunology and Infection, 2021
Objective: We aimed to analyze clinical outcomes from patients with severe COVID-19 pneumonia that received either baricitinib plus dexamethasone or dexamethasone monotherapy. Methodology: We performed a retrospective comparative study.
Eduardo Pérez-Alba, Laura Nuzzolo-Shihadeh, Gloria Mayela Aguirre-García, Jaime Espinosa-Mora, Juan Diego Lecona-Garcia, Romulo Omar Flores-Pérez, Marisela Mendoza-Garza, Adrián Camacho-Ortiz   +7 more
doaj   +1 more source

The Efficacy of High-Dose Dexamethasone vs. Other Treatments for Newly Diagnosed Immune Thrombocytopenia: A Meta-Analysis

Frontiers in Medicine, 2021
Objective: To compare the therapeutic efficacies of high dose dexamethasone, prednisone and rituximab in combination with dexamethasone for newly diagnosed ITP (Immune Thrombocytopenia, ITP) patients.Methods and results: Relevant publications for this ...
Qirong Xiao, Qirong Xiao, Bicun Lin, Bicun Lin, Hanyu Wang, Weiwu Zhan, Weiwu Zhan, Ping Chen, Ping Chen   +8 more
doaj   +1 more source